An efficient synthesis of taxotere side chain

Letters in Organic Chemistry

Volumn 6, Issue 8, 2009, Pages 616-618

  Devi, Joymati ^a   Saikia, Partha Pratim ^a   Barua, Nabin C ^a  

^a Natural Products Chemistry Division   (India)

Author keywords

Anticancer agents; Asymmetric Henry reaction; Asymmetric synthesis; La (R) BINOL; Taxol; Taxotere side chain

Indexed keywords

EID: 77249087159     PISSN: 15701786     EISSN: None     Source Type: Journal    
DOI: 10.2174/157017809790442871     Document Type: Article

References (15)

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15. The enantiomeric excess (ee) was measured by HPLC analysis carried out using a Waters 510 HPLC system. The HPLC conditions used for analysis were: Chiracel OD column, flow rate 0.8 mL/min, hexane/isopropanol 90 : 10, retention times (2R, 3S) 7.38 min (major isomer), (2S, 3S) 6.61 min (minor isomer).