Radiosynthesis of 4-[18F]fluoromethyl-L-phenylalanine and [ 18F]FET via a same strategy and automated synthesis module

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 53, Issue 2, 2010, Pages 58-62

  Kersemans, Ken ^a   Mertens, John ^a   Caveliers, Vicky ^a  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

Author keywords

Automation; PET; Radiosynthesis

Indexed keywords

AMINO ACIDS; CLINICAL RESEARCH; IMAGE PROCESSING; PROPIONIC ACID; TUMORS;

AMINO-ACIDS; AUTOMATED SYNTHESIS; DEFLUORINATION; HEAD-AND-NECK TUMOR; RADIOCHEMICAL PURITY; RADIOSYNTHESIS; STRATEGY SYNTHESIS; SYNTHESISED; TUMOR IMAGING; TUMOR IMAGING AGENTS;

AUTOMATION;

2 AMINO 3 (4 FLUOROMETHYL PHENYL)PROPIONIC ACID F 18; 4 FLUOROMETHYL PHENYLALANINE F 18; AMINO ACID DERIVATIVE; BROMIDE; FLUORINE 18; O (2' FLUOROETHYL)TYROSINE F 18; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ARTICLE; AUTOMATION; CATALYSIS; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); DEFLUORINATION; DEPROTECTION REACTION; DRUG FORMULATION; DRUG PURITY; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; POSITRON EMISSION TOMOGRAPHY; RADIOACTIVITY; RADIOCHEMISTRY; SHELF LIFE;

EID: 77249083130     PISSN: 03624803     EISSN: 10991344     Source Type: Journal    
DOI: 10.1002/jlcr.1701     Document Type: Article

References (11)

1. R. Michael, PET in Oncology, Springer, Berlin, Heidelberg, 2008.
2. K. J. Langen, K. Hamacher, M. Weckesser, F. Floeth, G. Stoffels, D. Bauer, H. H. Coenen, D. Pauleit, Nucl. Med. Biol. 2006, 33, 287-294.
3. D. Pauleit, A. Zimmermann, G. Stoffels, D. Bauer, J. Risse, M. O. Fluss, K. Hamacher, H. H. Coenen, K. J. Langen, J. Nucl. Med. 2006, 47, 256-261.
4. D. Pauleit, G. Stoffels, W. Schaden, K. Hamacher, D. Bauer, L. Tellmann, H. Herzog, S. Broeer, H. H. Coenen, K. J. Langen, J. Nucl. Med. 2005, 46, 411-416.
5. K. Kersemans, M. Bauwens, T. Lahoutte, A. Bossuyt, J. Mertens, Nucl. Instrum. Methods A. 2007, 571(1-2), 151-154.
6. K. Kersemans, M. Bauwens, J. Mertens, Nucl. Med. Biol. 2008, 35(4), 425-432.
7. V. Caveliers, K. Kersemans, T. Lahoutte, M. Bauwens, C. Vanhove, M. Keyaerts, J. Mertens, A. Bossuyt, H. Everaert, J. Nucl. Med. MEETING ABSTRACTS 2008, 49, 282.
8. H. Everaert, C. Chaskis, V. Caveliers, T. Lahoutte, J. Mertens, K. Kersemans, C. Vanhove, M. Bauwens, A. Bossuyt, B. Neyns, J. Nucl. Med. MEETING ABSTRACTS 2008, 49, 357.
9. K. Hamacher, H. H. Coenen, Appl. Rad. Isot. 2002, 57, 853-856.
10. B. H. Mock,W.Winkle, M. T. Vawrek,Nucl. Med. Biol. 1997, 24, 193-195.
11. M. A. Channinga, B. X. Huang, W. C. Eckelman, Nucl. Med. Biol. 2001, 28(4), 469-471.