Full resistance and decreased susceptibility to carbapenems in IMP-13-producing Pseudomonas aeruginosa isolates from an outbreak

Antimicrobial Agents and Chemotherapy

Volumn 54, Issue 3, 2010, Pages 1381-1382

  Santella, Gisela ^a   Cuirolo, Arabela ^a   Almuzara, Marisa ^b   Palombarani, Susana ^b   Sly, Gabriela ^b   Radice, Marcela ^a   Gutkind, Gabriel ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b Hospital Interzonal General de Agudos Eva Peronquot   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; CARBAPENEM; CEFAZOLIN; CEFEPIME; CEFTAZIDIME; CEFTRIAXONE; CIPROFLOXACIN; CLINDAMYCIN; COLISTIN; COTRIMOXAZOLE; EDETIC ACID; ERYTHROMYCIN; GENTAMICIN; IMIPENEM; MEROPENEM; METALLO BETA LACTAMASE; PIPERACILLIN PLUS TAZOBACTAM; RIFAMPICIN; SULTAMICILLIN; VANCOMYCIN;

ADULT; AGED; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; BACTERIUM CULTURE; BACTERIUM ISOLATE; CATHETER INFECTION; CLINICAL ARTICLE; DISK DIFFUSION; ENDOVASCULAR SEPSIS; ENZYME ACTIVITY; FEMALE; GENETIC SCREENING; HOSPITAL PATIENT; HUMAN; LETTER; LUNG LAVAGE; MALE; MINIMUM INHIBITORY CONCENTRATION; OSTEOMYELITIS; OUTCOME ASSESSMENT; PERITONITIS; POSTSURGICAL PERITONITIS; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; PULSED FIELD GEL ELECTROPHORESIS; SEPSIS; SKIN INFECTION; SOFT TISSUE INFECTION; VENTILATOR ASSOCIATED PNEUMONIA;

ANTI-BACTERIAL AGENTS; ARGENTINA; BACTERIAL PROTEINS; BETA-LACTAM RESISTANCE; BETA-LACTAMASES; CARBAPENEMS; CEFTAZIDIME; DISEASE OUTBREAKS; HUMANS; MICROBIAL SENSITIVITY TESTS; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS;

EID: 77149173724     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00399-09     Document Type: Letter

References (9)

1. Kolayli, F., A. Karadenizli, H. Savli, K. Ergen, O. Hatirnaz, E. Balikci, F. Budak, and H. Vahaboglu. 2004. Effect of carbapenems on the transcriptional expression of the oprD, oprM and oprN genes in Pseudomonas aeruginosa. J. Med. Microbiol. 53:915-920.
2. Li, X. Z., N. Barre, and K. Poole. 2000. Influence of the MexA-MexB-oprM multidrug efflux system on expression of the MexC-MexD-oprJ and MexE-MexF-oprN multidrug efflux systems in Pseudomonas aeruginosa. J. Antimicrob. Chemother. 46:885-893.
3. Livermore, D. M. 1995. β-Lactamases in laboratory and clinical resistance. Clin. Microbiol. Rev. 8:557-584.
4. Miranda, G., C. Kelly, F. Solorzano, B. Leanos, R. Coria, and J. E. Patterson. 1996. Use of pulsed-field gel electrophoresis typing to study an outbreak of infection due to Serratia marcescens in a neonatal intensive care unit. J. Clin. Microbiol. 34:3138-3141.
5. Pagani, L., C. Colinon, R. Migliavacca, M. Labonia, J. D. Docquier, E. Nucleo, M. Spalla, M. Li Bergoli, and G. M. Rossolini. 2005. Nosocomial outbreak caused by multidrug-resistant Pseudomonas aeruginosa producing IMP-13 metallo-beta-lactamase. J. Clin. Microbiol. 43:3824-3828.
6. Pagniez, G., M. Radice, A. Cuirolo, O. Rodriguez, H. Rodriguez, C. Vay, A. Famiglietti, and G. Gutkind. 2006. Prevalence of metallo-beta-lactamase in carbapenem resistant Pseudomonas aeruginosa at a University Hospital of Buenos Aires City. Rev. Argent. Microbiol. 38:33-37.
7. Quale, J., S. Bratu, J. Gupta, and D. Landman. 2006. Interplay of efflux system, ampC, and oprD expression in carbapenem resistance of Pseudomonas aeruginosa clinical isolates. Antimicrob. Agents Chemother. 50:1633-1641.
8. Rossi, A., H. Lopardo, M. Woloj, A. M. Picandet, M. Mariño, M. Galas, M. Radice, and G. Gutkind. 1995. Non-typhoid Salmonella spp. resistant to cefotaxime. J. Antimicrob. Chemother. 36:697-702.
9. Toleman, M., D. Biendach, D. Bennet, R. Jones, and T. Walsh. 2003. Genetic characterization of a novel metallo-beta-lactamase gene, blaIMP-13, harboured by a novel Tn5051-type transposon disseminating carbapenemase genes in Europe: report from the SENTRY worldwide antimicrobial surveillance programme. J. Antimicrob. Chemother. 52:583-590.