Increased product formation induced by a directed secondary substrate limitation in a batch Hansenula polymorpha culture

Applied Microbiology and Biotechnology

Volumn 86, Issue 1, 2010, Pages 93-101

  Kottmeier, Kirsten ^a,b   Müller, Carsten ^a,c   Huber, Robert ^a   Büchs, Jochen ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^c m2p labs GmbH   (Germany)

Author keywords

BioLector; Hansenula polymorpha; Process development; Respiration activity monitoring system; Secondary substrate limitation

Indexed keywords

BATCH CULTURE; BATCH FERMENTATION; BIOMASS PRODUCTIONS; CARBON SOURCE; FLUORESCENCE INTENSITIES; FORMATE DEHYDROGENASE; GREEN FLUORESCENT PROTEIN; HANSENULA POLYMORPHA; METABOLIC FLUX; METHYLOTROPHIC YEASTS; MICROTITER PLATES; ONLINE MONITORING; OXYGEN TRANSFER RATE; PROCESS DEVELOPMENT; PRODUCT FORMATION; RESPIRATION ACTIVITY MONITORING SYSTEMS; SCATTERED LIGHT; SHAKE FLASKS; SOLE CARBON SOURCE; SUBSTRATE LIMITATION;

BATCH CELL CULTURE; BOTTLES; FLUORESCENCE; GENE EXPRESSION; GLUCOSE; GLYCEROL; MAGNESIUM; MONITORING; OXYGEN; POTASSIUM;

SUBSTRATES;

CARBON; FORMATE DEHYDROGENASE; GLYCEROL; GREEN FLUORESCENT PROTEIN; MAGNESIUM; OXYGEN; PHOSPHATE; POTASSIUM;

GENE; GROWTH RATE; PHYTOMASS; SUBSTRATE; YEAST;

ARTICLE; BATCH FERMENTATION; BIOMASS PRODUCTION; CARBON SOURCE; CONTROLLED STUDY; FLUORESCENCE; FUNGUS CULTURE; GENE EXPRESSION; METHYLOTROPHIC YEAST; MICROTITER PLATE ASSAY; NONHUMAN; ONLINE MONITORING; OXYGEN TRANSPORT; PICHIA ANGUSTA;

BIOMASS; BIOREACTORS; CULTURE MEDIA; FERMENTATION; GENE EXPRESSION REGULATION, FUNGAL; GLUCOSE; GLYCEROL; GREEN FLUORESCENT PROTEINS; INDUSTRIAL MICROBIOLOGY; MAGNESIUM; OXYGEN CONSUMPTION; PHOSPHATES; PICHIA; POTASSIUM; SUBSTRATE SPECIFICITY;

PICHIA ANGUSTA;

EID: 77149173466     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-009-2285-0     Document Type: Article

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