Effect of para-aminobenzoic acid on the course of retinal degeneration in the rd10 mouse

Journal of Ocular Pharmacology and Therapeutics

Volumn 25, Issue 6, 2009, Pages 475-482

  Galbinur, Tural ^a   Obolensky, Alexey ^a   Berenshtein, Eduard ^b   Vinokur, Vladimir ^b   Chowers, Itay ^a   Chevion, Mordechai ^b   Banin, Eyal ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 DINITROPHENYLHYDRAZINE; 4 AMINOBENZOIC ACID; CARBONYL DERIVATIVE; OPSIN; SODIUM CHLORIDE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DARK ADAPTATION; DISEASE COURSE; ELECTROPHYSIOLOGY; ELECTRORETINOGRAM; EYE PROTECTION; IMMUNOHISTOCHEMISTRY; LIGHT ADAPTATION; LIPID PEROXIDATION; MOUSE; NONHUMAN; PERINATAL PERIOD; RETINA ROD; RETINITIS PIGMENTOSA;

4-AMINOBENZOIC ACID; ANIMALS; ANTIOXIDANTS; ELECTROPHYSIOLOGY; INJECTIONS, INTRAPERITONEAL; LIPID PEROXIDATION; MICE; MICE, INBRED C57BL; OXIDATIVE STRESS; PROTEIN CARBONYLATION; RETINAL DEGENERATION; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 77149159741     PISSN: 10807683     EISSN: None     Source Type: Journal    
DOI: 10.1089/jop.2009.0020     Document Type: Article

References (51)

1. Berson, E.L. Retinitis pigmentosa. The Friedenwald Lecture. Invest. Ophthalmol. Vis. Sci. 34:1659-1676, 1993.
2. Hartong, D.T., Berson, E.L., and Dryja, T.P. Retinitis pigmentosa. Lancet. 368:1795-1809, 2006.
3. Berson, E.L. Long-term visual prognoses in patients with retinitis pigmentosa: The Ludwig von Sallmann lecture. Exp. Eye Res. 85:7-14, 2007.
4. Travis, G.H. Mechanisms of cell death in the inherited retinal degenerations. Am. J. Hum. Genet. 62:503-508, 1998.
5. Sahel, J.A. Saving cone cells in hereditary rod diseases: a possible role for rod-derived cone viability factor (RdCVF) therapy. Retina. 25:S38-S39, 2005.
6. Carmody, R.J., McGowan, A.J., and Cotter, T.G. Reactive oxygen species as mediators of photoreceptor apoptosis in vitro. Exp. Cell Res. 248:520-530, 1999.
7. Carmody, R.J., and Cotter, T.G. Oxidative stress induces caspase- independent retinal apoptosis in vitro. Cell Death Differ. 7:282-291, 2000.
8. Ames, A., III. Energy requirements of CNS cells as related to their function and to their vulnerability to ischemia: a commentary based on studies on retina. Can. J. Physiol. Pharmacol. 70(Suppl):S158-S164, 1992.
9. Floyd, R.A. Antioxidants, oxidative stress, and degenerative neurological disorders. Proc. Soc. Exp. Biol. Med. 222:236-245, 1999.
10. Lin, M.T., and Beal, M.F. Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature. 443:787-795, 2006.
11. Sultana, R., Perluigi, M., and Butterfield, D.A. Protein oxidation and lipid peroxidation in brain of subjects with Alzheimer's disease: insights into mechanism of neurodegeneration from redox proteomics. Antioxid. Redox Signal. 8:2021-2037, 2006.
12. Loh, K.P., Huang, S.H., De Silva, R., et al. Oxidative stress: apoptosis in neuronal injury. Curr. Alzheimer Res. 3:327-337, 2006.
13. Tezel, G. Oxidative stress in glaucomatous neurodegeneration: mechanisms and consequences. Prog. Retin Eye Res.25:490-513, 2006.
14. Izzotti, A., Bagnis, A., and Sacca, S.C. The role of oxidative stress in glaucoma. Mutat. Res. 612:105-114, 2006.
15. Toda, N., and Nakanishi-Toda, M. Nitric oxide: ocular blood flow, glaucoma, and diabetic retinopathy. Prog. Retin. Eye Res. 26:205-238, 2007.
16. Decanini, A., Nordgaard, C.L., Feng, X., et al. Changes in select redox proteins of the retinal pigment epithelium in age-related macular degeneration. Am. J. Ophthalmol. 143:607-615, 2007.
17. Rajendram, R., Saraswathy, S., and Rao, N.A. Photoreceptor mitochondrial oxidative stress in early experimental autoimmune uveoretinitis. Br. J. Ophthalmol. 91:531-537, 2007.
18. Suzuki, M., Kamei, M., Itabe, H., et al. Oxidized phospholipids in the macula increase with age and in eyes with age-related macular degeneration. Mol. Vis. 13:772-778, 2007.
19. Shen, J., Yang, X., Dong, A., et al. Oxidative damage is a potential cause of cone cell death in retinitis pigmentosa. J. Cell Physiol. 203:457-464, 2005.
20. Padnick-Silver, L., Derwent, J.J., Giuliano, E., et al. Retinal oxygenation and oxygen metabolism in Abyssinian cats with a hereditary retinal degeneration. Invest. Ophthalmol. Vis. Sci. 47:3683-3689, 2006. (Pubitemid 351639738)
21. Mendes, H.F., van der Spuy, J., Chapple, J.P., et al. Mechanisms of cell death in rhodopsin retinitis pigmentosa: implications for therapy. Trends Mol. Med. 11:177-185, 2005.
22. Ahuja-Jensen, P., Johnsen-Soriano, S., Ahuja, S., et al. Low glutathione peroxidase in rd1 mouse retina increases oxidative stress and proteases. Neuroreport. 18:797-801, 2007.
23. Deleon, E., Lederman, M., Berenstein, E., et al. Alteration in Iron Metabolism During Retinal Degeneration in rd10 Mouse. Invest. Ophthalmol. Vis. Sci. 50:1360-1365, 2009.
24. Sanz, M.M., Johnson, L.E., Ahuja, S., et al. Significant photoreceptor rescue by treatment with a combination of antioxidants in an animal model for retinal degeneration. Neuroscience. 145:1120-1129, 2007.
25. Komeima, K., Rogers, B.S., Lu, L., et al. Antioxidants reduce cone cell death in a model of retinitis pigmentosa. Proc. Natl Acad. Sci. USA. 103:11300-11305, 2006.
26. Komeima, K., Rogers, B.S., and Campochiaro, P.A. Antioxidants slow photoreceptor cell death in mouse models of retinitis pigmentosa. J. Cell. Physiol. 213:809-815, 2007.
27. Schmidt-Erfurth, U. Nutrition and retina. Dev. Ophthalmol. 38:120-147, 2005.
28. Eter, N., Krohne, T.U., and Holz, F.G. New pharmacologic approaches to therapy for age-related macular degeneration. BioDrugs. 20:167-179, 2006. (Pubitemid 43845337)
29. Akberova, S.I., Ershov, F.I., Musaev Galbinur, P.I., et al. [Time course of interferon status of patients with herpetic keratitis during treatment with actipol, a new inteferon inducer]. Vestn. Oftalmol. 117:33-36, 2001.
30. Akberova, S.I. [New biological properties of p-aminobenzoic acid]. Izv. Akad. Nauk. Ser. Biol. 4:477-481, 2002.
31. Gichner, T., Veleminsky, J., Rapoport, I.A., et al. Antimutagenic effect of p-aminobenzoic acid on the mutagenicity of N-methyl- N-nitro-N- nitrosoguanidine in Salmonella typhimurium. Mutat. Res. 192:95-98, 1987.
32. Gichner, T., and Veleminsky, J. Inhibitors of N-nitroso compounds- induced mutagenicity. Mutat. Res. 195:21-43, 1988.
33. Ramaiia, L.K., Pomerantseva, M.D., and Malashenko, A.M. [Effects of para-aminobenzoic acid on radiosensitivity of mice of different strains]. Radiats. Biol. Radioecol. 42:169-172, 2002.
34. Esposito, M., Vannozzi, M.O., Viale, M., et al. Para-aminobenzoic acid suppression of cis-diamminedichloroplatinum(II) nephrotoxicity. Carcinogenesis. 14:2595-2599, 1993. (Pubitemid 24016602)
35. Esposito, M., Vannozzi, M., Viale, M., et al. Effect of para-aminobenzoic acid on the pharmacokinetics and urinary excretion of cis- diamminedichloroplatinum(II) in rats. Anticancer Res. 15:2541-2547, 1995.
36. Drozd, N.N., Makarov, V.A., Miftakhova, N.T., et al. [Antithrombotic activity of para-aminobenzoic acid]. Eksp. Klin. Farmakol. 63:40-44, 2000.
37. Richards, R.M., and Xing, D.K. Investigation of synergism between combinations of ciprofl oxacin, polymyxin, sulphadiazine and p-aminobenzoic acid. J. Pharm. Pharmacol. 45:171-175, 1993.
38. Akberova, S.I., Musaev Galbinur, P.I., Stroeva, O.G., et al. [Comparative evaluation of the antioxidant activity of paraaminobenzoic acid and emoxipin in the cornea and crystalline lens (an experimental study)]. Vestn. Oftalmol. 117:25-29, 2001.
39. Akberova, S.I., Musaev Galbinur, P.I., Magomedov, N.M., et al. [Comparative assessment of antioxidant activity of para-aminobenzoic acid and emoxipin in retina]. Vestn. Oftalmol. 114:39-44, 1998.
40. Stroeva, O.G., Poplinskaia, V.A., Khoroshilova-Maslova, I.P., et al. [The stimulation of membrane disk formation on the outer segments of rat photoreceptor cells by using para-aminobenzoic acid]. Dokl. Akad. Nauk. SSSR. 314:483-487, 1990.
41. Stroeva, O.G., Ershov, A.V., Poplinskaia, V.A., et al. [The interorgan distribution of tritium-labelled para-aminobenzoic acid in the body of rats after its subcutaneous injection]. Izv. Akad. Nauk. Ser. Biol. 3:459-462, 1992.
42. Chang, B., Hawes, N.L., Hurd, R.E., et al. Retinal degeneration mutants in the mouse. Vision Res. 42:517-525, 2002.
43. Gargini, C., Terzibasi, E., Mazzoni, F., et al. Retinal organization in the retinal degeneration 10 (rd10) mutant mouse: a morphological and ERG study. J. Comp. Neurol. 500:222-238, 2007.
44. Barhoum, R., Martinez-Navarrete, G., Corrochano, S., et al. Functional and structural modifications during retinal degeneration in the rd10 mouse. Neuroscience. 155:698-713, 2008.
45. Applebury, M.L., Antoch, M.P., Baxter, L.C., et al. The murine cone photoreceptor: a single cone type expresses both S and M opsins with retinal spatial patterning. Neuron. 27:513-523, 2000.
46. Osborne, N.N., and Wood, J.P. Metipranolol blunts nitric oxideinduced lipid peroxidation and death of retinal photoreceptors: a comparison with other anti-glaucoma drugs. Invest. Ophthalmol. Vis. Sci. 45:3787-3795, 2004.
47. Levine, R.L., Williams, J.A., Stadtman, E.R., et al. Carbonyl assays for determination of oxidatively modified proteins. Methods Enzymol. 233:346-357, 1994.
48. Kantor, G.R., and Ratz, J.L. Liver toxicity from potassium paraaminobenzoate. J. Am. Acad. Dermatol. 13:671-672, 1985.
49. Vinnicombe, H.G., and Derrick, J.P. Dihydropteroate synthase from Streptococcus pneumoniae: characterization of substrate binding order and sulfonamide inhibition. Biochem. Biophys. Res. Commun. 258:752-757, 1999.
50. Mohand-Said, S., Deudon-Combe, A., Hicks, D., et al. Normal retina releases a diffusible factor stimulating cone survival in the retinal degeneration mouse. Proc. Natl Acad. Sci. USA. 95:8357-8362, 1998.
51. Ripps, H. Cell death in retinitis pigmentosa: gap junctions and the "bystander" effect. Exp. Eye Res. 74:327-336, 2002.