Aminoglycoside-induced deafness during treatment of acute leukaemia

Archives of Disease in Childhood

Volumn 95, Issue 2, 2010, Pages 153-155

  Bitner Glindzicz, Maria ^a,b   Osei Lah, V ^a,c   Colvin, I ^d   Sirimanna, T ^a   Lucas, D ^d   Mac Ardle, B ^d   Webb, D ^a   Shankar, A ^e   Kingston, J ^a,e   Jenkins, L ^a   Rahman, S ^a,f  

^a GREAT ORMOND STREET HOSPITAL   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c QUEEN ALEXANDRA HOSPITAL   (United Kingdom)

^d ROYAL NATIONAL THROAT NOSE AND EAR HOSPITAL   (United Kingdom)

^e ROYAL LONDON HOSPITAL   (United Kingdom)

^f NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE; GENTAMICIN; KANAMYCIN; MITOCHONDRIAL DNA; ANTIBIOTIC AGENT;

ACUTE LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ALTERNATIVE MEDICINE; ANTIBIOTIC THERAPY; ARTICLE; CANCER REGRESSION; CASE REPORT; CHILD; COCHLEA PROSTHESIS; DRUG BLOOD LEVEL; EXTRACHROMOSOMAL INHERITANCE; FEMALE; FOLLOW UP; GENE MUTATION; GENETIC ANALYSIS; HEARING IMPAIRMENT; HUMAN; LANGUAGE DISABILITY; MALE; OTOTOXICITY; PRE B LYMPHOCYTE; PRESCHOOL CHILD; PRIORITY JOURNAL; PURE TONE AUDIOMETRY; SCREENING TEST; SEPSIS; B CELL ACUTE LYMPHOBLASTIC LEUKEMIA; NEUTROPENIA; NEUTROPENIC SEPSIS;

AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; CHILD, PRESCHOOL; DEAFNESS; DNA, MITOCHONDRIAL; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MUTATION; OPPORTUNISTIC INFECTIONS; PEDIGREE; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA;

EID: 77149140442     PISSN: 00039888     EISSN: 14682044     Source Type: Journal    
DOI: 10.1136/adc.2009.158220     Document Type: Article

References (6)

1. Usami S, Abe S, Shinkawa H, et al. Sensorineural hearing loss caused by mitochondrial DNA mutations: special reference to the A1555G mutation. J Commun Disord 1998;31:423-34.
2. Bitner-Glindzciz M, Pembrey ME, Duncan AJ, et al. Prevalence of mitochondrial 1555ARG mutation in European children. N Engl J Med 2009;360:640-2.
3. Li Z, Li R, Chen J, et al. Mutational analysis of the mitochondrial 12S rRNA gene in Chinese pediatric subjects with aminoglycoside-induced and non-syndromic hearing loss. Hum Genet 2005;117:9-15.
4. Hobbie SN, Bruell CM, Akshay S, et al. Mitochondrial deafness alleles confer misreading of the genetic code. Proc Natl Acad Sci U S A 2008;105:3244-9.
5. Barton GR, Stacey PC, Fortnum HM, et al. Hearing-impaired children in the United Kingdom, II: Cochlear implantation and the cost of compulsory education. Ear Hear 2006;27:187-207.
6. Bitner-Glindzicz M, Rahman S. Ototoxicity caused by aminoglycosides. BMJ 2007;335:784-5.