Inflammatory bowel disease activity assessed by fecal calprotectin and lactoferrin: Correlation with laboratory parameters, clinical, endoscopic and histological indexes

BMC Research Notes

Volumn 2, Issue , 2009, Pages

  Vieira, Andrea ^a   Fang, Chia Bin ^b   Rolim, Ernani Geraldo ^a   Klug, Wilmar Artur ^b   Steinwurz, Flvio ^c   Rossini, Lucio Giovanni Battista ^d   Candelria, Paulo Azevedo ^b  

^a Clinic of Gastroenterology   (Brazil)

^b Service of Coloproctology   (Brazil)

^c HOSPITAL ISRAELITA ALBERT EINSTEIN   (Brazil)

^d Service of Endoscopy of Irmandade Santa Casa de so Paulo   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 77149139853     PISSN: None     EISSN: 17560500     Source Type: Journal    
DOI: 10.1186/1756-0500-2-221     Document Type: Article

References (27)

1. Role of fecal calprotectin as a biomarker of intestinal inflammation in inflammatory bowel disease. MR Konikoff LA Denson, Inflamm Bowel Dis 2006 12 524 534 10.1097/00054725-200606000-00013 16775498
2. Comparison of 4 neutrophil-derived proteins in feces as indicators of disease activity in ulcerative colitis. J Langhorst S Elsenbruch T Mueller, et al. Inflamm Bowel Dis 2005 11 1085 1091 10.1097/01.MIB.0000187980.08686.18 16306771
3. Questions and answers on the role of fecal calprotectin as a biological marker in inflammatory bowel disease. JP Gisbert AG Mcnicholl, Inflamm Bowel Dis 2009 41 1 56 66
4. Fecal calprotectin levels predict colorectal inflammation among patients with chronic diarrhea referred for colonoscopy. PJ Limburg DA Ahlquist WJ Sandborn, et al. Am J Gastroenterol 2000 95 2831 2837 10.1111/j.1572-0241.2000. 03194.x 11051356
5. Review article: biological activity markers in inflammatory bowel disease. D Desai WA Faubion WJ Sandborn, Aliment Pharmacol Ther 2007 25 247 255 17217454
6. Fecal calprotectin in first-degree relatives of patients with ulcerative colitis. M Montalto V Curigliano L Santoro, et al. Am J Gastroenterol 2007 102 132 136 10.1111/j.1572-0241.2006.00884.x 17100982
7. Fecal lactoferrin is a sensitive and specific marker in identifying intestinal inflammation. SV Kane WJ Sandborn PA Rufo, et al. Am J Gastroenterol 2003 98 1309 1314 10.1111/j.1572-0241.2003.07458.x 12818275
8. Fecal calprotectin: validation as a noninvasive measure of bowel inflammation in childhood inflammatory bowel disease. SK Bunn WM Bisset MJ Main, et al. J Pediatr Gastroenterol Nutr 2001 33 14 22 10.1097/00005176-200107000- 00003 11479402
9. Colorectal inflammation is well predicted by fecal calprotectin in children with gastrointestinal symptoms. UL Fagerberg L Loof U Myrdal, et al. J Pediatr Gastroenterol Nutr 2005 40 450 455 10.1097/01.MPG.0000154657.08994.94 15795593
10. Fecal leukocyte proteins in inflammatory bowel disease and irritable bowel syndrome. H Silberer B Kuppers O Mickisch, et al. Clin Lab 2005 51 117 26 15819166
11. A simple method for assessing intestinal inflammation in Crohn's disease. J Tibble K Teahon B Thjodleifsson, et al. Gut 2000 47 506 513 10986210 10.1136/gut.47.4.506
12. Assessment of the neutrophil dominating protein Calprotectin in feces. A methodologic study. AG Roseth MK Fagerhol E Aadland H Schjonsby, Scand J Gastroenterol 1992 27 793 798 10.3109/00365529209011186 1411288
13. Relationship between fecal Calprotectin intestinal inflammation, and peripheral blood neutrophils in patients with active ulcerative colitis. H Hanai K Takeuchi T Lida, et al. Dig Dis Sci 2004 49 1438 1443 10.1023/B:DDAS. 0000042243.47279.87 15481316
14. Fecal Calprotectin as an index of intestinal inflammation. JA Tibble I Bjarnason, Drugs Today(Barc) 2001 37 85 96 12783101
15. Diagnostic value of fecal calprotectin in predicting na abnormal colonoscopy. V Garcia Sanchez Mdel R Gonzalez E Iglesias Flores, et al. Med Clin (Barc) 2006 127 41 46 10.1157/13090002 16801001
16. Diagnostic value of faecal calprotectin in paediatric gastroenterology clinical practice. R Berni Canani L Rapacciuolo MT Romano, et al. Dig Liver Dis 2004 36 467 470 10.1016/j.dld.2004.02.009 15285526
17. Normalization of faecal Calprotectin: a predictor of mucosal healing in patients with inflammatory bowel disease. AG Roseth E Aadland K Grzyb, Scand J Gastroenterol 2004 39 1017 1020 10.1080/00365520410007971 15513345
18. Assessment of disease activity in ulcerative colitis by faecal calprotectin, a novel granulocyte marker protein. AG Roseth E Aadland J Jahnsen, et al. Digestion 1997 58 176 180 10.1159/000201441 9144308
19. Correlation between faecal excretion of indium-111-labelled granulocytes and calprotectin, a granulocyte marker protein, in patients with inflammatory bowel disease. AG Roseth PN Schmidt MK Fagerhol, Scand J Gastroenterol 1999 34 50 54 10.1080/00365529950172835 10048733
20. Faecal calprotectin: a marker of inflammation throughout the intestinal tract. CB Summerton MG Longlands K Wiener, et al. Eur J Gastroenterol Hepatol 2002 14 841 845 10.1097/00042737-200208000-00005 12172403
21. Role of faecal calprotectin as non-invasive marker of intestinal inflammation. F Costa MG Mumolo M Bellini, et al. Dig Liver Dis 2003 35 642 647 10.1016/S1590-8658(03)00381-5 14563186
22. Calprotectin and lactoferrin in the assessment of intestinal inflammation and organic disease. R D'Inca E Dal Pont Leo Di, et al. Int J Colorectal Dis 2007 22 429 437 10.1007/s00384-006-0159-9 16838143
23. Faecal Calprotectin: a bright future for assessing disease activity in Crohn's disease. DR Gaya JF Mackenzie, QJM 2002 95 557 558 10.1093/qjmed/95.9. 557 12205332
24. Assessment of endoscopic activity index and biological inflammatory markers in clinically active Crohn's disease with normal C-protein serum level. MA Denis C Reenaers F Fontaine J Belaiche E Louis, Inflamm Bowel Dis 2007 13 1100 1105 10.1002/ibd.20178 17508418
25. Crohn's disease activity assessed by fecal Calprotectin and lactoferrin: Correlation with Crohn's disease activity index and endoscopic findings. T Sipponen E Savilahti KL Kolho H Nuutinen U Turunen M Farkkila, Inflamm Bowel Dis 2008 14 1 40 6 10.1002/ibd.20312 18022866
26. Calprotectin is a stronger predictive marker of relapse in ulcerative colitis than in Crohn'sdisease. F Costa MG Mumolo L Ceccarelli, et al. Gut 2005 54 364 368 15710984 10.1136/gut.2004.043406 (Pubitemid 40299092)
27. Diagnostic precision of fecal Calprotectin for inflammatory bowel disease and colorectal malignancy. AC von Roon L Karamountzos S Purkayastha, et al. Am J Gastroenterol 2007 102 803 813 10.1111/j.1572-0241.2007.01126.x 17324124