Modulation of HOXA10 and other markers of endometrial receptivity by age and human chorionic gonadotropin in an endometrial explant model

Fertility and Sterility

Volumn 93, Issue 4, 2010, Pages 1255-1259

  Fogle, Robin H ^a,b   Li, Aimin ^b   Paulson, Richard J ^b  

^a Atlanta Center for Reproductive Medicine   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

embryo implantation; Endometrial receptivity; glycodelin; HOXA10; vascular endothelial growth factor

Indexed keywords

CHORIONIC GONADOTROPIN; ESTRADIOL; KI 67 ANTIGEN; MESSENGER RNA; PLACENTA PROTEIN 14; PROGESTERONE; TRANSCRIPTION FACTOR HOXA10; VASCULOTROPIN;

ADULT; AGE DISTRIBUTION; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOMETRIUM; ENDOMETRIUM BIOPSY; EPITHELIUM; EXPLANT; FEMALE; GENE EXPRESSION; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MEDICAL RESEARCH; MODULATION; MOLECULAR BIOLOGY; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUANTITATIVE ANALYSIS; STROMA; UTERUS;

ADULT; AGE FACTORS; AGING; BIOLOGICAL MARKERS; CELL SURVIVAL; CHORIONIC GONADOTROPIN; EMBRYO IMPLANTATION; ENDOMETRIUM; FEMALE; HOMEODOMAIN PROTEINS; HUMANS; INFERTILITY, FEMALE; MIDDLE AGED; TISSUE CULTURE TECHNIQUES;

EID: 77049126644     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2008.11.002     Document Type: Article

References (21)

1. Licht P., Russu V., and Wildt L. On the role of human chorionic gonadotropin (hCG) in the embryo-endometrial microenvironment: implications for differentiation and implantation. Semin Reprod Med 19 (2001) 37-47
2. Reshef E., Lei A.M., Rao C.V., Pridham D.D., Chegini N., and Luborsky J.L. The presence of gonadotropin receptors in nonpregnant human uterus, human placenta, fetal membranes, and decidua. J Clin Endocrinol Metab 70 (1990) 421-430
3. Han S.W., Lei Z.M., and Rao C.V. Treatment of human endometrial stromal cells with chorionic gonadotropin promotes their morphological and functional differentiation into decidua. Mol Cell Endocrinol 147 (1999) 7-16
4. Nemansky M., Moy E., Lyons C.D., Yu I., and Blithe D.L. Human endometrial stromal cells generate uncombined alpha-subunit from human chorionic gonadotropin, which can synergize with progesterone to induce decidualization. J Clin Endocrinol Metab 83 (1998) 575-581
5. Fazleabas A.T., Donnelly K.M., Srinivasan S., Fortman J.D., and Miller J.B. Modulation of the baboon (Papio Anubis) uterine endometrium by chorionic gonadotrophin during the period of uterine receptivity. Proc Natl Acad Sci U S A 96 (1999) 2543-2548
6. Srisuparp S., Strakova Z., and Fazleabas A.T. The role of chorionic gonadotropin (CG) in blastocyst implantation. Arch Med Res 32 (2001) 627-634
7. Sauer M.V., Paulson R.J., and Lobo R.A. Reversing the natural decline in human fertility: an extended clinical trial of oocyte donation to women of advanced reproductive age. JAMA 268 (1992) 1275-1279
8. Marbaix E., Donnez J., Courtoy P.J., and Eeckhout Y. Progesterone regulates the activity of collagenase and related gelatinases A and B in human endometrial explants. Proc Natl Acad Sci U S A 89 (1992) 11789-11793
9. Osteen K.G., Rodgers W.H., Gaire M., Hargrove J.T., Gorstein F., and Matrisian L.M. Stromal-epithelial interaction mediates steroidal regulation of metalloproteinase expression in human endometrium. Proc Natl Acad Sci U S A 91 (1994) 10129-10133
10. Jain J.K., Li A., Nucatola D.L., Minoo P., and Felix J.C. Nonoxynol-9 induces apoptosis of endometrial explants by both caspase-dependent and independent apoptotic pathways. Biol Reprod 73 (2005) 382-388
11. Hansis C., Patel S., Stanczyk F.Z., and Paulson R.J. Measurement of hCG in culture media: a promising marker for selecting high-potential preimplantation human embryos. Fertil Steril 84 Suppl 1 (2005) S90
12. Gerdes J., Lemke H., Baisch H., Wacker H.H., Schwab U., and Stein H. Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. J Immunol 133 (1984) 1710-1715
13. Jain J.K., Li A., Yang W., Minoo P., and Felix J.C. Effects of mifepristone on proliferation and apoptosis of human endometrium in new users of medroxyprogesterone acetate. Hum Reprod 21 (2006) 798-809
14. - ΔΔCt method. Methods 25 (2001) 402-408
15. Dudley D.J., Hatasaka H.H., Branch D.W., Hammond E., and Mitchell M.D. A human endometrial explant system: validation and potential applications. Am J Obstet Gynecol 167 (1992) 1774-1780
16. Nucatola D.L., Li A., Nicosia A.F., Felix J.C., and Jain J.K. The effect of mifepristone on estrogen receptors following treatment with medroxyprogesterone acetate in cultured human endometrial explants. Fertil Steril 80 (2003) S53
17. Sakkas D., Lu C., Zulfikaroglu E., Neuber E., and Taylor H.S. A soluble molecule secreted by human blastocysts modulates regulation of HOXA10 expression in an epithelial endometrial cell line. Fertil Steril 80 (2003) 1169-1174
18. Paulson R.J., Hatch I.E., Lobo R.A., and Sauer M.V. Cumulative conception and live birth rates after oocyte donation: implications regarding endometrial receptivity. Hum Reprod 12 (1997) 835-839
19. Sauer M.V., Paulson R.J., Ary B.A., and Lobo R.A. Three hundred cycles of oocyte donation at the University of Southern California: assessing the effect of age and infertility diagnosis on pregnancy and implantation rates. J Assist Reprod Genet 11 (1994) 92-96
20. Legro R.S., Wong I.L., Paulson R.J., Lobo R.A., and Sauer M.V. Recipient's age does not adversely affect pregnancy outcome after oocyte donation. Am J Obstet Gynecol 172 (1995) 96-100
21. Toner J.P., Grainger D.A., and Frazier L.M. Clinical outcomes among recipients of donated eggs: an analysis of the U.S. national experience, 1996-1998. Fertil Steril 78 (2002) 1038-1045