NT-proBNP is associated with coronary heart disease risk in healthy older women but fails to enhance prediction beyond established risk factors: Results from the British Women's Heart and Health Study

Atherosclerosis

Volumn 209, Issue 1, 2010, Pages 295-299

  Sattar, Naveed ^a   Welsh, Paul ^a   Sarwar, Nadeem ^b   Danesh, John ^b   Di Angelantonio, Emanuele ^b   Gudnason, Vilmundur ^c   Smith, George Davey ^d   Ebrahim, Shah ^e   Lawlor, Debbie A ^d  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c ICELANDIC HEART ASSOCIATION   (Iceland)

^d UNIVERSITY OF BRISTOL   (United Kingdom)

^e LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

Coronary heart disease; Epidemiology; Natriuretic peptides; NT proBNP; Risk factors; Women

Indexed keywords

ACETYLSALICYLIC ACID; AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE; C REACTIVE PROTEIN; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INSULIN; LIPID;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; CONTROLLED STUDY; CORONARY RISK; DISEASE MARKER; FEMALE; HUMAN; HYPERTENSION; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; PHYSICAL ACTIVITY; POPULATION RISK; PREDICTION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RISK ASSESSMENT; RISK FACTOR; SMOKING; SOCIAL CLASS; UNITED KINGDOM; WAIST HIP RATIO; WOMEN'S HEALTH;

BIOLOGICAL MARKERS; CORONARY DISEASE; ENGLAND; FEMALE; HUMANS; MIDDLE AGED; NATRIURETIC PEPTIDE, BRAIN; PEPTIDE FRAGMENTS; PROGNOSIS; RISK FACTORS;

EID: 77049119448     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2009.09.016     Document Type: Article

References (23)

1. Swedberg K., Cleland J., Dargie H., et al. Guidelines for the diagnosis and treatment of chronic heart failure: executive summary (update 2005): The Task Force for the Diagnosis and Treatment of Chronic Heart Failure of the European Society of Cardiology. Eur Heart J 26 (2005) 1115-1140
2. Heeschen C., Hamm C.W., Mitrovic V., Lantelme N.H., and White H.D. N-terminal pro-B-type natriuretic peptide levels for dynamic risk stratification of patients with acute coronary syndromes. Circulation 110 (2004) 3206-3212
3. Blankenberg S., McQueen M.J., Smieja M., et al. Comparative impact of multiple biomarkers and N-Terminal pro-brain natriuretic peptide in the context of conventional risk factors for the prediction of recurrent cardiovascular events in the Heart Outcomes Prevention Evaluation (HOPE) Study. Circulation 114 (2006) 201-208
4. Emberson J.R., Ng L.L., Armitage J., Bowman L., Parish S., and Collins R. N-terminal Pro-B-type natriuretic peptide, vascular disease risk, and cholesterol reduction among 20,536 patients in the MRC/BHF heart protection study. J Am Coll Cardiol 49 (2007) 311-319
5. Bibbins-Domingo K., Gupta R., Na B., Wu A.H., Schiller N.B., and Whooley M.A. N-terminal fragment of the prohormone brain-type natriuretic peptide (NT-proBNP), cardiovascular events, and mortality in patients with stable coronary heart disease. JAMA 297 (2007) 169-176
6. De Sutter J., De Bacquer D., Cuypers S., et al. Plasma N-terminal pro-brain natriuretic peptide concentration predicts coronary events in men at work: a report from the BELSTRESS study. Eur Heart J 26 (2005) 2644-2649
7. Kistorp C., Raymond I., Pedersen F., Gustafsson F., Faber J., and Hildebrandt P. N-terminal pro-brain natriuretic peptide, C-reactive protein, and urinary albumin levels as predictors of mortality and cardiovascular events in older adults. JAMA 293 (2005) 1609-1616
8. Olsen M.H., Hansen T.W., Christensen M.K., et al. N-terminal pro-brain natriuretic peptide, but not high sensitivity C-reactive protein, improves cardiovascular risk prediction in the general population. Eur Heart J 28 (2007) 1374-1381
9. Wang T.J., Larson M.G., Levy D., et al. Plasma natriuretic peptide levels and the risk of cardiovascular events and death. N Engl J Med 350 (2004) 655-663
10. Zethelius B., Berglund L., Sundstrom J., et al. Use of multiple biomarkers to improve the prediction of death from cardiovascular causes. N Engl J Med 358 (2008) 2107-2116
11. Melander O., Newton-Cheh C., Almgren P., et al. Novel and conventional biomarkers for prediction of incident cardiovascular events in the community. JAMA 302 1 (2009) 49-57
12. Shi X., Xu G., Xia T., Song Y., and Lin Q. N-terminal-pro-B-type natriuretic peptide (NT-proBNP): reference range for Chinese apparently healthy people and clinical performance in Chinese elderly patients with heart failure. Clin Chim Acta 360 (2005) 122-127
13. Lawlor D.A., Bedford C., Taylor M., and Ebrahim S. Geographical variation in cardiovascular disease, risk factors, and their control in older women: British Women's Heart and Health Study. J Epidemiol Community Health 57 (2003) 134-140
14. Sattar N., Watt P., Cherry L., Ebrahim S., Davey Smith G., and Lawlor D.A. High molecular weight adiponectin is not associated with incident coronary heart disease in older women: a nested prospective case-control study. J Clin End Metab 93 (2008) 1846-1849
15. Lawlor D.A., Davey Smith G.D., and Ebrahim S. Does the new International Diabetes Federation definition of the metabolic syndrome predict CHD any more strongly than older definitions? Findings from the British Women's Heart and Health Study. Diabetologia 49 (2006) 41-48
16. Prentice R.L., and Breslow N.E. Retrospective studies and failure time models. Biometika 65 (1978) 153-158
17. Rothman K.J., and Greenland S. Modern epidemiology. 2nd ed. (1998), Lippincott-Raven, Philadelphia
18. Justice A.C., Covinsky K.E., and Berlin J.A. Assessing the generalizability of prognostic information. Ann Intern Med 130 (1999) 515-524
19. Pencina M.J., D'Agostino Sr. R.B., D'Agostino Jr. R.B., and Vasan R.S. Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond. Stat Med 27 (2008) 157-172
20. Olsen M.H., Hansen T.W., Christensen M.K., et al. N-terminal pro brain natriuretic peptide is inversely related to metabolic cardiovascular risk factors and the metabolic syndrome. Hypertension 46 (2005) 660-666
21. McEntegart M.B., Awede B., Petrie M.C., et al. Increase in serum adiponectin concentration in patients with heart failure and cachexia: relationship with leptin, other cytokines, and B-type natriuretic peptide. Eur Heart J 28 (2007) 829-835
22. Ang D.S., Welsh P., Watt P.H., Nelson S.M., Struthers A.D., and Sattar N. Serial changes in adiponectin and BNP in ACS patients: paradoxical associations with each other and with prognosis. Clin Sci (Lond) 117 (2009) 41-48
23. Sattar N., Murray H.M., Welsh P., et al. Are markers of inflammation more strongly associated with risk for fatal than for nonfatal vascular events?. PLoS Med 6 6 (2009) e1000099