PCSK4-null sperm display enhanced protein tyrosine phosphorylation and ADAM2 proteolytic processing during in vitro capacitation

Fertility and Sterility

Volumn 93, Issue 4, 2010, Pages 1112-1123

  Gyamera Acheampong, Charles ^a,b   Vasilescu, Julian ^b   Figeys, Daniel ^b   Mbikay, Majambu ^a,b,c  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

^c UNIVERSITY OF OTTAWA   (Canada)

Author keywords

acrosome reaction; capacitation; cholesterol efflux; PCSK4; Proprotein convertase; tyrosine phosphorylation

Indexed keywords

ADAM PROTEIN; ALBUMIN; CALCIUM; CHOLESTEROL; CYCLIC AMP DEPENDENT PROTEIN KINASE; LIGAND; METALLOPROTEINASE; PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 4; PROTEIN ADAM 2; PROTEIN ADAM 3; PROTEIN TYROSINE KINASE; SERINE PROTEINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHOLESTEROL TRANSPORT; CONGENIC STRAIN; CONTROLLED STUDY; EGG; EPIDIDYMIS; EPIDIDYMIS TAIL; FERTILIZATION; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; NULL ALLELE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; SPERM; SPERMATOZOON CAPACITATION; UNIVERSITY HOSPITAL; WILD TYPE;

ADAM PROTEINS; AMINO ACID SEQUENCE; ANIMALS; CELL LINE; HUMANS; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, CONGENIC; MICE, INBRED C57BL; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; PEPTIDE HYDROLASES; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; SERINE ENDOPEPTIDASES; SPERM CAPACITATION; SPERMATOZOA; TYROSINE;

EID: 77049100806     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2008.12.013     Document Type: Article

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