Effects of stress on the immune response to theiler's virus - implications for virus-induced autoimmunity

NeuroImmunoModulation

Volumn 17, Issue 3, 2010, Pages 169-172

  Welsh, C Jane ^a   Steelman, Andrew J ^a   Mi, Wentao ^a   Young, Colin R ^a   Dean, Dana D ^a   Storts, Ralph ^a   Welsh Jr , Thomas H ^b   Meagher, Mary W ^b  

^a TEXAS A AND M UNIVERSITY   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Adaptive immunity; Innate immunity; Multiple sclerosis; Restraint stress; Theiler's virus

Indexed keywords

DEXAMETHASONE; GAMMA INTERFERON; MESSENGER RNA; MIFEPRISTONE; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET; VIRUS PROTEIN;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; AUTOIMMUNITY; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL ACTIVITY; CELL ISOLATION; CELL STIMULATION; CELLULAR STRESS RESPONSE; CENTRAL NERVOUS SYSTEM; CHRONIC STRESS; CONFERENCE PAPER; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEMYELINATING DISEASE; DEMYELINATION; DISEASE COURSE; DISEASE PREDISPOSITION; DISEASE SEVERITY; GENE EXPRESSION; HISTOLOGY; HORMONE RELEASE; IMMOBILIZATION STRESS; IMMUNE DEFICIENCY; IMMUNE RESPONSE; IMMUNOPATHOGENESIS; INNATE IMMUNITY; MOUSE; MULTIPLE SCLEROSIS; MURINE ENCEPHALOMYELITIS VIRUS; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; T LYMPHOCYTE; TH1 CELL; TH2 CELL; VIRUS IMMUNITY; VIRUS INFECTION; VIRUS LOAD; VIRUS REPLICATION;

ANIMALS; AUTOIMMUNITY; CARDIOVIRUS INFECTIONS; CYTOKINES; GLUCOCORTICOIDS; HUMANS; IMMUNE TOLERANCE; MICE; MULTIPLE SCLEROSIS; STRESS, PSYCHOLOGICAL; T-LYMPHOCYTES, HELPER-INDUCER; THEILOVIRUS;

EID: 76949099458     PISSN: 10217401     EISSN: None     Source Type: Journal    
DOI: 10.1159/000258715     Document Type: Conference Paper

References (10)

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2. Campbell T, Meagher MW, Sieve A, Scott B, Storts R, Welsh TH, Welsh CJR: The effects of restraint stress on the neuropathogenesis of Theiler's virus infection. I. Acute disease. Brain Behav Immun 2001; 15: 235-254.
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6. Johnson RR, Prentice T, Bridegam P, Young CR, Steelman AJ, Welsh TH, Welsh CJR, Meagher MW: Social stress alters the severity and onset of the chronic phase of Theiler's virus infection. J Neuroimmunol 2006; 175: 39-51.
7. Mi W, Young CR, Storts R, Steelman A, Meagher MW, Welsh CJR: Stress alters pathogenicity and facilitates systemic dissemination of Theiler's virus. Microb Pathogen 2006; 41: 133-143. (Pubitemid 44374295)
8. Mi W, Prentice TW, Young CR, Johnson RR, Sieve AN, Meagher MW, Welsh CJR: Restraint stress decreases virus-induced proinflammatory cytokine expression during acute Theiler's virus infection. J Neuroimmunol 2006; 178: 49-61.
9. Steelman AJ, Dean DD, Young CR, Smith R, Prentice TW, Meagher MW, Welsh CJR: Restraint stress modulates virus specific adaptive immunity during acute Theiler's virus infection. Brain Behav Immun 2009; 23: 830-843.
10. Meagher MW, Sieve AN, Johnson RR, Satterlee D, Belyavskyi M, Mi W, Prentice TW, Welsh TH, Welsh CJR: Neonatal maternal separation alters immune, endocrine, and behavioral responses to acute Theiler's virus infection in adult mice. Behav Genet 2009;in press.