Assessment of adherence problems in patients with serious and persistent mental illness: Recommendations from the expert consensus guidelines

Journal of Psychiatric Practice

Volumn 16, Issue 1, 2010, Pages 34-45

  Velligan, Dawn I ^a   Weiden, Peter J ^b   Sajatovic, Martha ^c   Scott, Jan ^d   Carpenter, Daniel ^e   Ross, Ruth ^f   Docherty, John P ^g  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c CASE WESTERN RESERVE UNIVERSITY   (United States)

^d ROYAL VICTORIA INFIRMARY   (United Kingdom)

^e Univ S Carolina Sch Med Vice P   (United States)

^f Ross Editorial ^*  (United States)

^g Cornell University ^*  (United States)

Author keywords

Adherence; Assessment; Bipolar disorder; Expert consensus guidelines; Medication; Schizophrenia

Indexed keywords

BEHAVIOR; CLINICAL PRACTICE; COMORBIDITY; DEMOGRAPHY; FAMILY; HEALTH CARE DELIVERY; HEALTH SURVEY; HUMAN; MENTAL DISEASE; PATIENT ASSESSMENT; REVIEW; SCHIZOPHRENIA; SELF REPORT; SOCIAL SUPPORT;

ANTIPSYCHOTIC AGENTS; ATTITUDE; BIPOLAR DISORDER; HOSPITALS, GROUP PRACTICE; HUMANS; MENTAL DISORDERS; PATIENT COMPLIANCE; PHYSICIAN-PATIENT RELATIONS; PSYCHOTROPIC DRUGS; SCHIZOPHRENIA; SELF DISCLOSURE;

EID: 76849098872     PISSN: 15274160     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.pra.0000367776.96012.ca     Document Type: Review

References (43)

1. Velligan DI, Lam F, Ereshefsky L, et al. Psychopharmacology: Perspectives on medication adherence and atypical antipsychotic medications. Psychiatr Serv 2003;54:665-667
2. Velligan DI,Weiden PJ, Sajatovic M, et al. The expert consensus guideline series: Adherence problems in patients with serious and persistent mental illness. J Clin Psychiatry 2009;70(suppl 4). (Available at www.psychiatrist. com/private/supplenet/v70s04, accessed December 15, 2009).
3. Velligan DI, Wang M, Diamond P, et al. Relationships among subjective and objective measures of adherence to oral antipsychotic medications. Psychiatr Serv 2007;58: 1187-1192
4. Eaddy M, Grogg A, Locklear J. Assessment of compliance with antipsychotic treatment and resource utilization in a Medicaid population. Clin Ther 2005;27:263-272
5. Velligan DI, Lam YW, Glahn DC, et al. Defining and assessing adherence to oral antipsychotics: A review of the literature. Schizophr Bull 2006;32:724-742
6. Byerly M, Fisher R, Whatley K, et al. A comparison of electronic monitoring vs. clinician rating of antipsychotic adherence in outpatients with schizophrenia. Psychiatry Res 2005;133:129-133
7. Byerly MJ, Thompson A, Carmody T, et al. Validity of electronically monitored medication adherence and conventional adherence measures in schizophrenia. Psychiatr Serv 2007;58:844-847
8. Nakonezny PA, Byerly MJ, Rush AJ. Electronic monitoring of antipsychotic medication adherence in outpatients with schizophrenia or schizoaffective disorder: An empirical evaluation of its reliability and predictive validity. Psychiatry Res 2008;157:259-263
9. Harvey NS, Peet M. Lithium maintenance: 2. Effects of personality and attitude on health information acquisition and compliance. Br J Psychiatry 1991;158:200-204
10. Scott J, Pope M. Nonadherence with mood stabilizers: Prevalence and predictors. J Clin Psychiatry 2002;63: 384-390
11. Kinon BJ, Hill AL, Liu H, et al. Olanzapine orally disintegrating tablets in the treatment of acutely ill non-compliant patients with schizophrenia. Int J Neuropsychopharmacol 2003;6:97-102.
12. Woltmann EM, Valenstein M,Welsh DE, et al. Using pharmacy data on partial adherence to inform clinical care of patients with serious mental illness. Psychiatr Serv 2007;58:864-867
13. Naditz A. Medication compliance-helping patients through technology: Modern "smart" pillboxes keep memory-short patients on their medical regimen. Telemedicine and e- Health 2008;14:875-880 (available at www.liebertonline.com toc/tmj/14/9).
14. Dolder CR, Lacro JP,Warren KA, et al. Brief evaluation of medication influences and beliefs: Development and testing of a brief scale for medication adherence. J Clin Psychopharmacol 2004;24:404-409
15. Fialko L, Garety PA, Kuipers E, et al. A large-scale validation study of the Medication Adherence Rating Scale (MARS). Schizophr Res 2008;100:53-59
16. Thompson K, Kulkarni J, Sergejew AA. Reliability and validity of a new Medication Adherence Rating Scale (MARS) for the psychoses. Schizophr Res 2000;42:241-247
17. Morisky DE, Green LW, Levine DM. Concurrent and predictive validity of a self-reported measure of medication adherence. Med Care 1986;24:67-74.
18. Byerly MJ, Nakonezny PA, Rush AJ. The Brief Adherence Rating Scale (BARS) validated against electronic monitoring in assessing the antipsychotic medication adherence of outpatients with schizophrenia and schizoaffective disorder. Schizophr Res 2008;100:60-69
19. Weiden PJ. Understanding and addressing adherence issues in schizophrenia: From theory to practice. J Clin Psychiatry 2007;68(suppl 14):14-19
20. Sajatovic M, Valenstein M, Blow F, et al. Treatment adherence with lithium and anticonvulsant medications among patients with bipolar disorder. Psychiatr Serv 2007;58: 855-863 (Pubitemid 46985180)
21. Nosé M, Barbui C, Tansella M. How often do patients with psychosis fail to adhere to treatment programmes? A systematic review. Psychol Med 2003;33:1149-1160
22. Valenstein M, Blow FC, Copeland LA, et al. Poor antipsychotic adherence among patients with schizophrenia: Medication and patient factors. Schizophr Bull 2004;30: 255-264
23. Sajatovic M, Elhaj O, Youngstrom EA, et al. Treatment adherence in individuals with rapid cycling bipolar disorder: Results from a clinical-trial setting. J Clin Psychopharmacol 2007;27:412-414
24. Baldessarini RJ, Perry R, Pike J. Factors associated with treatment nonadherence among US bipolar disorder patients. Hum Psychopharmacol 2008;23:95-105.
25. Sajatovic M, Valenstein M, Blow FC, et al. Treatment adherence with antipsychotic medications in bipolar disorder. Bipolar Disord 2006;8:232-241
26. Diaz E, Woods SW, Rosenheck RA. Effects of ethnicity on psychotropic medications adherence. Community Ment Health J 2005;41:521-537
27. Ahn J, McCombs JS, Jung C, et al. Classifying patients by antipsychotic adherence patterns using latent class analysis: Characteristics of nonadherent groups in the California Medicaid (Medi-Cal) program. Value Health 2008;11:48-56.
28. Copeland LA, Zeber JE, Salloum IM, et al. Treatment adherence and illness insight in veterans with bipolar disorder. J Nerv Ment Dis 2008;196:16-21.
29. Jeste SD, Patterson TL, Palmer BW, et al. Cognitive predictors of medication adherence among middle-aged and older outpatients with schizophrenia. Schizophr Res 2003;63:49-58.
30. Maples NJ, Velligan DI, Ritch JL, et al. Assessing the ability to take medication. Schizophr Bull. In press
31. Robinson DG, Woerner MG, Alvir JM, et al. Predictors of medication discontinuation by patients with first-episode schizophrenia and schizoaffective disorder. Schizophr Res 2002;57:209-219
32. McCann TV, Boardman G, Clark E, et al. Risk profiles for non-adherence to antipsychotic medications. J Psychiatr Ment Health Nurs 2008;15:622-629
33. Johnson FR, Ozdemir S, Manjunath R, et al. Factors that affect adherence to bipolar disorder treatments: A statedpreference approach. Med Care 2007;45:545-552
34. Perkins DO. Predictors of noncompliance in patients with schizophrenia. J Clin Psychiatry 2002;63:1121-1128
35. Masand PS, Narasimhan M. Improving adherence to antipsychotic pharmacotherapy. Curr Clin Pharmacol 2006;1:47-56.
36. Lecomte T, Spidel A, Leclerc C, et al. Predictors and profiles of treatment non-adherence and engagement in services problems in early psychosis. Schizophr Res 2008;102: 295-302.
37. Tunis SL, Faries DE, Stensland MD, et al. An examination of factors affecting persistence with initial antipsychotic treatment in patients with schizophrenia. Curr Med Res Opin 2007;23:97-104.
38. Zeber JE, Copeland LA, Good CB, et al. Therapeutic alliance perceptions and medication adherence in patients with bipolar disorder. J Affect Disord 2008;107:53-62.
39. Fenton WS, Blyler CR, Heinssen RK. Determinants of medication compliance in schizophrenia: Empirical and clinical findings. Schizophr Bull 1997;23:637-651
40. Hudson TJ, Owen RR, Thrush CR, et al. A pilot study of barriers to medication adherence in schizophrenia. J Clin Psychiatry 2004;65:211-216
41. Zeber JE, Grazier KL, Valenstein M, et al. Effect of a medication copayment increase in veterans with schizophrenia. Am J Manag Care 2007;13(6 Pt 2):335-346
42. Sajatovic M, Biswas K, Kilbourne AK, et al. Factors associated with prospective long-term treatment adherence among individuals with bipolar disorder. Psychiatr Serv 2008;59:753-759
43. Bowskill R, Clatworthy J, Parham R, et al. Patients' perceptions of information received about medication prescribed for bipolar disorder: Implications for informed choice. J Affect Disord 2007;100:253-257