-
1
-
-
13944263525
-
Mutational analysis of hepatitis C virus nonstructural protein 5A: Potential role of differential phosphorylation in RNA replication and identification of a genetically flexible domain
-
Appel, N., Pietschmann, T. & Bartenschlager, R. (2005). Mutational analysis of hepatitis C virus nonstructural protein 5A: potential role of differential phosphorylation in RNA replication and identification of a genetically flexible domain. J Virol 79, 3187-3194.
-
(2005)
J Virol
, vol.79
, pp. 3187-3194
-
-
Appel, N.1
Pietschmann, T.2
Bartenschlager, R.3
-
2
-
-
36549040859
-
The selectivity of protein kinase inhibitors: A further update
-
Bain, J., Plater, L., Elliott, M., Shpiro, N., Hastie, C. J., McLauchlan, H., Klevernic, I., Arthur, J. S., Alessi, D. R. & Cohen, P. (2007). The selectivity of protein kinase inhibitors: a further update. Biochem J 408, 297-315.
-
(2007)
Biochem J
, vol.408
, pp. 297-315
-
-
Bain, J.1
Plater, L.2
Elliott, M.3
Shpiro, N.4
Hastie, C.J.5
McLauchlan, H.6
Klevernic, I.7
Arthur, J.S.8
Alessi, D.R.9
Cohen, P.10
-
3
-
-
0036893332
-
Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication
-
Blight, K. J., McKeating, J. A. & Rice, C. M. (2002). Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication. J Virol 76, 13001-13014.
-
(2002)
J Virol
, vol.76
, pp. 13001-13014
-
-
Blight, K.J.1
McKeating, J.A.2
Rice, C.M.3
-
4
-
-
0032582678
-
Direct inhibition of cyclooxygenase-1 and -2 by the kinase inhibitors SB 203580 and PD 98059. SB 203580 also inhibits thromboxane synthase
-
Borsch-Haubold, A. G., Pasquet, S. & Watson, S. P. (1998). Direct inhibition of cyclooxygenase-1 and -2 by the kinase inhibitors SB 203580 and PD 98059. SB 203580 also inhibits thromboxane synthase. J Biol Chem 273, 28766-28772.
-
(1998)
J Biol Chem
, vol.273
, pp. 28766-28772
-
-
Borsch-Haubold, A.G.1
Pasquet, S.2
Watson, S.P.3
-
5
-
-
1842457779
-
High-throughput screening of the yeast kinome: Identification of human serine/threonine protein kinases that phosphorylate the hepatitis C virus NS5A protein
-
Coito, C., Diamond, D. L., Neddermann, P., Korth, M. J. & Katze, M. G. (2004). High-throughput screening of the yeast kinome: identification of human serine/threonine protein kinases that phosphorylate the hepatitis C virus NS5A protein. J Virol 78, 3502-3513.
-
(2004)
J Virol
, vol.78
, pp. 3502-3513
-
-
Coito, C.1
Diamond, D.L.2
Neddermann, P.3
Korth, M.J.4
Katze, M.G.5
-
6
-
-
0028228616
-
Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells
-
Cowley, S., Paterson, H., Kemp, P. & Marshall, C. J. (1994). Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell 77, 841-852.
-
(1994)
Cell
, vol.77
, pp. 841-852
-
-
Cowley, S.1
Paterson, H.2
Kemp, P.3
Marshall, C.J.4
-
7
-
-
0034306450
-
Specificity and mechanism of action of some commonly used protein kinase inhibitors
-
Davies, S. P., Reddy, H., Caivano, M. & Cohen, P. (2000). Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J 351, 95-105.
-
(2000)
Biochem J
, vol.351
, pp. 95-105
-
-
Davies, S.P.1
Reddy, H.2
Caivano, M.3
Cohen, P.4
-
8
-
-
14444279192
-
-
Favata, M. F., Horiuchi, K. Y., Manos, E. J., Daulerio, A. J., Stradley, D. A., Feeser, W. S., Van Dyk, D. E., Pitts, W. J., Earl, R. A. & other authors (1998). Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J Biol Chem 273, 18623-18632.
-
Favata, M. F., Horiuchi, K. Y., Manos, E. J., Daulerio, A. J., Stradley, D. A., Feeser, W. S., Van Dyk, D. E., Pitts, W. J., Earl, R. A. & other authors (1998). Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J Biol Chem 273, 18623-18632.
-
-
-
-
9
-
-
0037319845
-
Suppression of the ERK1/2 signaling pathway from HCV NS5A protein expressed by herpes simplex recombinant viruses
-
Georgopoulou, U., Caravokiri, K. & Mavromara, P. (2003). Suppression of the ERK1/2 signaling pathway from HCV NS5A protein expressed by herpes simplex recombinant viruses. Arch Virol 148, 237-251.
-
(2003)
Arch Virol
, vol.148
, pp. 237-251
-
-
Georgopoulou, U.1
Caravokiri, K.2
Mavromara, P.3
-
10
-
-
33644796737
-
Mechanistic link between the anti-HCV effect of interferon gamma and control of viral replication by a Ras-MAPK signaling cascade
-
Huang, Y., Chen, X. C., Konduri, M., Fomina, N., Lu, J., Jin, L., Kolykhalov, A. & Tan, S. L. (2006). Mechanistic link between the anti-HCV effect of interferon gamma and control of viral replication by a Ras-MAPK signaling cascade. Hepatology 43, 81-90.
-
(2006)
Hepatology
, vol.43
, pp. 81-90
-
-
Huang, Y.1
Chen, X.C.2
Konduri, M.3
Fomina, N.4
Lu, J.5
Jin, L.6
Kolykhalov, A.7
Tan, S.L.8
-
11
-
-
70349728564
-
A conserved proline between domains II and III of hepatitis C virus NS5A influences both RNA replication and virus assembly
-
Hughes, M., Gretton, S., Shelton, H., Brown, D. D., McCormick, C. J., Angus, A. G., Patel, A. H., Griffin, S. & Harris, M. (2009). A conserved proline between domains II and III of hepatitis C virus NS5A influences both RNA replication and virus assembly. J Virol 83, 10788-10796.
-
(2009)
J Virol
, vol.83
, pp. 10788-10796
-
-
Hughes, M.1
Gretton, S.2
Shelton, H.3
Brown, D.D.4
McCormick, C.J.5
Angus, A.G.6
Patel, A.H.7
Griffin, S.8
Harris, M.9
-
12
-
-
0035032237
-
Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations
-
Krieger, N., Lohmann, V. & Bartenschlager, R. (2001). Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations. J Virol 75, 4614-4624.
-
(2001)
J Virol
, vol.75
, pp. 4614-4624
-
-
Krieger, N.1
Lohmann, V.2
Bartenschlager, R.3
-
13
-
-
0345188811
-
Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line
-
Lohmann, V., Korner, F., Koch, J., Herian, U., Theilmann, L. & Bartenschlager, R. (1999). Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line. Science 285, 110-113.
-
(1999)
Science
, vol.285
, pp. 110-113
-
-
Lohmann, V.1
Korner, F.2
Koch, J.3
Herian, U.4
Theilmann, L.5
Bartenschlager, R.6
-
14
-
-
4544336360
-
Hepatitis C virus NS5A: Tales of a promiscuous protein
-
Macdonald, A. & Harris, M. (2004). Hepatitis C virus NS5A: tales of a promiscuous protein. J Gen Virol 85, 2485-2502.
-
(2004)
J Gen Virol
, vol.85
, pp. 2485-2502
-
-
Macdonald, A.1
Harris, M.2
-
15
-
-
0038719743
-
The hepatitis C virus non-structural NS5A protein inhibits activating P-protein-1 function by perturbing Ras-ERK pathway signaling
-
Macdonald, A., Crowder, K., Street, A., McCormick, C., Saksela, K. & Harris, M. (2003). The hepatitis C virus non-structural NS5A protein inhibits activating P-protein-1 function by perturbing Ras-ERK pathway signaling. J Biol Chem 278, 17775-17784.
-
(2003)
J Biol Chem
, vol.278
, pp. 17775-17784
-
-
Macdonald, A.1
Crowder, K.2
Street, A.3
McCormick, C.4
Saksela, K.5
Harris, M.6
-
16
-
-
16844362861
-
Perturbation of epidermal growth factor receptor complex formation and Ras signalling in cells harbouring the hepatitis C virus subgenomic replicon
-
Macdonald, A., Chan, J. K. & Harris, M. (2005a). Perturbation of epidermal growth factor receptor complex formation and Ras signalling in cells harbouring the hepatitis C virus subgenomic replicon. J Gen Virol 86, 1027-1033.
-
(2005)
J Gen Virol
, vol.86
, pp. 1027-1033
-
-
Macdonald, A.1
Chan, J.K.2
Harris, M.3
-
17
-
-
20144387095
-
Further studies on hepatitis C virus NS5A-SH3 domain interactions: Identification of residues critical for binding and implications for viral RNA replication and modulation of cell signalling
-
Macdonald, A., Mazaleyrat, S., McCormick, C., Street, A., Burgoyne, N. J., Jackson, R. M., Cazeaux, V., Shelton, H., Saksela, K. & Harris, M. (2005b). Further studies on hepatitis C virus NS5A-SH3 domain interactions: identification of residues critical for binding and implications for viral RNA replication and modulation of cell signalling. J Gen Virol 86, 1035-1044.
-
(2005)
J Gen Virol
, vol.86
, pp. 1035-1044
-
-
Macdonald, A.1
Mazaleyrat, S.2
McCormick, C.3
Street, A.4
Burgoyne, N.J.5
Jackson, R.M.6
Cazeaux, V.7
Shelton, H.8
Saksela, K.9
Harris, M.10
-
18
-
-
49749092090
-
The hepatitis C virus non-structural protein NS5A alters the trafficking profile of the epidermal growth factor receptor
-
Mankouri, J., Griffin, S. & Harris, M. (2008). The hepatitis C virus non-structural protein NS5A alters the trafficking profile of the epidermal growth factor receptor. Traffic 9, 1497-1509.
-
(2008)
Traffic
, vol.9
, pp. 1497-1509
-
-
Mankouri, J.1
Griffin, S.2
Harris, M.3
-
19
-
-
23944482498
-
Enhancement of internal ribosome entry site-mediated translation and replication of hepatitis C virus by PD98059
-
Murata, T., Hijikata, M. & Shimotohno, K. (2005). Enhancement of internal ribosome entry site-mediated translation and replication of hepatitis C virus by PD98059. Virology 340, 105-115.
-
(2005)
Virology
, vol.340
, pp. 105-115
-
-
Murata, T.1
Hijikata, M.2
Shimotohno, K.3
-
20
-
-
33644856599
-
The SH3 binding motif of HCV NS5A protein interacts with Bin1 and is important for apoptosis and infectivity
-
Nanda, S. K., Herion, D. & Liang, T. J. (2006). The SH3 binding motif of HCV NS5A protein interacts with Bin1 and is important for apoptosis and infectivity. Gastroenterology 130, 794-809.
-
(2006)
Gastroenterology
, vol.130
, pp. 794-809
-
-
Nanda, S.K.1
Herion, D.2
Liang, T.J.3
-
21
-
-
8644290077
-
Reduction of hepatitis C virus NS5A hyperphosphorylation by selective inhibition of cellular kinases activates viral RNA replication in cell culture
-
Neddermann, P., Quintavalle, M., Di Pietro, C., Clementi, A., Cerretani, M., Altamura, S., Bartholomew, L. & De Francesco, R. (2004). Reduction of hepatitis C virus NS5A hyperphosphorylation by selective inhibition of cellular kinases activates viral RNA replication in cell culture. J Virol 78, 13306-13314.
-
(2004)
J Virol
, vol.78
, pp. 13306-13314
-
-
Neddermann, P.1
Quintavalle, M.2
Di Pietro, C.3
Clementi, A.4
Cerretani, M.5
Altamura, S.6
Bartholomew, L.7
De Francesco, R.8
-
22
-
-
50049095679
-
Altered expression of cell cycle and apoptotic proteins in chronic hepatitis C virus infection
-
Sarfraz, S., Hamid, S., Siddiqui, A., Hussain, S., Pervez, S. & Alexander, G. (2008). Altered expression of cell cycle and apoptotic proteins in chronic hepatitis C virus infection. BMC Microbiol 8, 133.
-
(2008)
BMC Microbiol
, vol.8
, pp. 133
-
-
Sarfraz, S.1
Hamid, S.2
Siddiqui, A.3
Hussain, S.4
Pervez, S.5
Alexander, G.6
-
23
-
-
0346373690
-
Virus-host cell interactions during hepatitis C virus RNA replication: Impact of polyprotein expression on the cellular transcriptome and cell cycle association with viral RNA synthesis
-
Scholle, F., Li, K., Bodola, F., Ikeda, M., Luxon, B. A. & Lemon, S. M. (2004). Virus-host cell interactions during hepatitis C virus RNA replication: impact of polyprotein expression on the cellular transcriptome and cell cycle association with viral RNA synthesis. J Virol 78, 1513-1524.
-
(2004)
J Virol
, vol.78
, pp. 1513-1524
-
-
Scholle, F.1
Li, K.2
Bodola, F.3
Ikeda, M.4
Luxon, B.A.5
Lemon, S.M.6
-
24
-
-
0033545996
-
NS5A, a nonstructural protein of hepatitis C virus, binds growth factor receptor-bound protein 2 adaptor protein in a Src homology 3 domain/liganddependent manner and perturbs mitogenic signaling
-
Tan, S. L., Nakao, H., He, Y., Vijaysri, S., Neddermann, P., Jacobs, B. L., Mayer, B. J. & Katze, M. G. (1999). NS5A, a nonstructural protein of hepatitis C virus, binds growth factor receptor-bound protein 2 adaptor protein in a Src homology 3 domain/liganddependent manner and perturbs mitogenic signaling. Proc Natl Acad Sci U S A 96, 5533-5538.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 5533-5538
-
-
Tan, S.L.1
Nakao, H.2
He, Y.3
Vijaysri, S.4
Neddermann, P.5
Jacobs, B.L.6
Mayer, B.J.7
Katze, M.G.8
-
25
-
-
27644586455
-
Development and characterization of a transient-replication assay for the genotype 2a hepatitis C virus subgenomic replicon
-
Targett-Adams, P. & McLauchlan, J. (2005). Development and characterization of a transient-replication assay for the genotype 2a hepatitis C virus subgenomic replicon. J Gen Virol 86, 3075-3080.
-
(2005)
J Gen Virol
, vol.86
, pp. 3075-3080
-
-
Targett-Adams, P.1
McLauchlan, J.2
-
26
-
-
43949109962
-
Acetylsalicylic acid inhibits hepatitis C virus RNA and protein expression through cyclooxygenase 2 signaling pathways
-
Trujillo-Murillo, K., Rincon-Sanchez, A. R., Martinez-Rodriguez, H., Bosques-Padilla, F., Ramos-Jimenez, J., Barrera-Saldana, H. A., Rojkind, M. & Rivas-Estilla, A. M. (2008). Acetylsalicylic acid inhibits hepatitis C virus RNA and protein expression through cyclooxygenase 2 signaling pathways. Hepatology 47, 1462-1472.
-
(2008)
Hepatology
, vol.47
, pp. 1462-1472
-
-
Trujillo-Murillo, K.1
Rincon-Sanchez, A.R.2
Martinez-Rodriguez, H.3
Bosques-Padilla, F.4
Ramos-Jimenez, J.5
Barrera-Saldana, H.A.6
Rojkind, M.7
Rivas-Estilla, A.M.8
-
27
-
-
22544447811
-
Hepatitis C virus stimulates the expression of cyclooxygenase-2 via oxidative stress: Role of prostaglandin E2 in RNA replication
-
Waris, G. & Siddiqui, A. (2005). Hepatitis C virus stimulates the expression of cyclooxygenase-2 via oxidative stress: role of prostaglandin E2 in RNA replication. J Virol 79, 9725-9734.
-
(2005)
J Virol
, vol.79
, pp. 9725-9734
-
-
Waris, G.1
Siddiqui, A.2
-
28
-
-
0037405824
-
Interleukin-1 inhibits hepatitis C virus subgenomic RNA replication by activation of extracellular regulated kinase pathway
-
Zhu, H. & Liu, C. (2003). Interleukin-1 inhibits hepatitis C virus subgenomic RNA replication by activation of extracellular regulated kinase pathway. J Virol 77, 5493-5498.
-
(2003)
J Virol
, vol.77
, pp. 5493-5498
-
-
Zhu, H.1
Liu, C.2
|