A modified low-cost colorimetric method for paracetamol (acetaminophen) measurement in plasma

Clinical Toxicology

Volumn 48, Issue 1, 2010, Pages 42-46

  Shihana, Fathima ^a,b   Dissanayake, Dhammika ^a,b   Dargan, Paul ^c,d   Dawson, Andrew ^a,e  

^a UNIVERSITY OF PERADENIYA   (Sri Lanka)

^b UNIVERSITY OF PERADENIYA   (Sri Lanka)

^c GUY'S AND ST THOMAS' NHS FOUNDATION TRUST   (United Kingdom)

^d KING'S COLLEGE LONDON   (United Kingdom)

^e UNIVERSITY OF NEWCASTLE   (Australia)

Author keywords

Acetaminophen; Acute poisoning; Acute renal failure; Analytical; Quantitative analysis

Indexed keywords

ACETYLCYSTEINE; PARACETAMOL;

ARTICLE; COHORT ANALYSIS; COLORIMETRY; COST EFFECTIVENESS ANALYSIS; DRUG INTOXICATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MAJOR CLINICAL STUDY; PROSPECTIVE STUDY; ROOM TEMPERATURE; SRI LANKA; VALIDATION PROCESS;

ACETAMINOPHEN; ACETYLCYSTEINE; ANALGESICS, NON-NARCOTIC; ANTIDOTES; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COHORT STUDIES; COLORIMETRY; HUMANS; INDICATORS AND REAGENTS; PROSPECTIVE STUDIES; REPRODUCIBILITY OF RESULTS; SRI LANKA;

EID: 76749170676     PISSN: 15563650     EISSN: 15569519     Source Type: Journal    
DOI: 10.3109/15563650903443137     Document Type: Article

References (25)

1. Daly FFS, Fountain JS, Murray L, Graudins A, Buckley NA. Guidelines for the management of paracetamol poisoning in Australia and New Zealand-explanation and elaboration. Med J Aust 2008; 188:296.
2. Dawson AH, Whyte IM. Therapeutic drug monitoring in drug overdose. Br J Clin Pharmacol 1999; 48:278-283.
3. Dart RC, Erdman AR, Olson KR, Christianson G, Manoguerra AS, Chyka PA, Caravati EM, Wax PM, Keyes DC, Woolf AD, Scharman EJ, Booze LL, Troutman WG. Acetaminophen poisoning: an evidence-based consensus guideline for out-of-hospital management. Clin Toxicol (Phila) 2006; 44:1-18. (Pubitemid 44112959)
4. Lall SB, Paul R. Paracetamol poisoning in children. Indian J Pediatr 1998; 65:393-400.
5. Paudyal BP. Poisoning: pattern and profile of admitted cases in a hospital in central Nepal. JNMA J Nepal Med Assoc 2005; 44:92-96.
6. Senarathna SM, Ranganathan SS, Dawson AH, Buckley N, Fernandopulle BM. Management of acute paracetamol poisoning in a tertiary care hospital. Ceylon Med J 2008; 53:89-92.
7. Fernando R. Management of poisoning. Colombo: The National poison Information Centre, National Hospital of Sri Lanka; 2007.
8. Glynn JP, Kendal SE. Letter: paracetamol measurement. Lancet 1975; 1:1147-1148.
9. Dargan P, Jones A. Effects of legislation restricting pack sizes of paracetamol on self poisoning. It's too early to tell yet. BMJ 2001; 323:633.
10. Shihabi ZK, David RM. Colorimetric assay for acetaminophen in serum. Ther Drug Monit 1984; 6:449-453.
11. Gupta RN, Pickersgill R, Stefanec M. Colorimetric determination of acetaminophen. Clin Biochem 1983; 16:220-221.
12. Nagaraja P, Murthy KC, Rangappa KS. Spectrophotometric method for the determination of paracetamol and phenacetin. J Pharm Biomed Anal 1998; 17:501-506.
13. Egleston CV, Browning C, Hamdi I, Campbell-Hewson G, Robinson SM. Comparison of two assays for measuring plasma concentrations of paracetamol. BMJ 1997; 315:991-992.
14. Senyuva H, Ozden T. Simultaneous high-performance liquid chromatographic determination of paracetamol, phenylephrine HCl, and chlorpheniramine maleate in pharmaceutical dosage forms. J Chromatogr Sci 2002; 40:97-100.
15. Hannothiaux MH, Houdret N, Lhermitte M, Izydorczak J, Roussel P. High performance liquid chromatographic determination of paracetamol in human serum. Ann Biol Clin (Paris) 1986; 44:139-141.
16. Becherucci C, Runci FM, Segre G. Gas chromatographic determination of paracetamol in plasma. Farmaco 1981; 36:312-316.
17. Dechtiaruk WA, Johnson GF, Solomon HM. Gas-chromatographic method for acetaminophen (N-acetyl-p-aminophenol) based on sequential alkylation. Clin Chem 1976; 22:879-883.
18. Chu Q, Jiang L, Tian X, Ye J. Rapid determination of acetaminophen and p-aminophenol in pharmaceutical formulations using miniaturized capillary electrophoresis with amperometric detection. Anal Chim Acta 2008; 606:246-251.
19. Bertholf RL, Johannsen LM, Bazooband A, Mansouri V. False-positive acetaminophen results in a hyperbilirubinemic patient. Clin Chem 2003; 49:695-698.
20. Polson J, Wians FH, Orsulak P, Fuller D, Murray NG, Koff JM, Khan AI, Balko JA, Hynan LS, Lee WM, Acute Liver Failure Study Group. False positive acetaminophen concentrations in patients with liver injury. Clin Chim Acta 2008; 391:24-30.
21. Archer CT, Richardson RA. An improved colorimetric method for the determination of plasma paracetamol. Ann Clin Biochem 1980; 17:45-46.
22. Longlands MG, Wiener K. Minimisation of salicylate interference in the Glynn and Kendal paracetamol procedure. Ann Clin Biochem 1982; 19:187-190.
23. Buttery JE, Braiotta EA, Pannall PR. Plasma acetaminophen results are method dependent. J Toxicol Clin Toxicol 1982; 19:1117-1122.
24. Bridges RR, Kinniburgh DW, Keehn BJ, Jennison TA. An evaluation of common methods for acetaminophen quantitation for small hospitals. J Toxicol Clin Toxicol 1983; 20:1-17.
25. Bailey DN. Colorimetry of serum acetaminophen (paracetamol) in uremia. Clin Chem 1982; 28:187-190.