Preparation of self-assembled microspheres and their potential for drug delivery

Pharmaceutical Development and Technology

Volumn 15, Issue 1, 2010, Pages 105-111

  Mellors, Rachel ^a   Benzeval, Ian ^b   Eisenthal, Robert ^c   Hubble, John ^b  

^a UNIVERSITY OF BATH   (United Kingdom)

^b University of Bath   (United Kingdom)

^c NONE

Author keywords

Dextran; Hydrogel; Release

Indexed keywords

BOVINE SERUM ALBUMIN; DEXTRAN; MICROSPHERE; POLYMER;

ARTICLE; DRUG DELIVERY SYSTEM; KINETICS; MOLECULAR WEIGHT; MORPHOLOGY; PARTICLE SIZE; PRECIPITATION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; TURBIDITY; ULTRAVIOLET SPECTROPHOTOMETRY; CHEMISTRY; SOLUBILITY; TIME;

CHEMICAL PRECIPITATION; DEXTRANS; DRUG DELIVERY SYSTEMS; MICROSPHERES; PARTICLE SIZE; POLYMERS; SERUM ALBUMIN, BOVINE; SOLUBILITY; TIME FACTORS;

EID: 76749170234     PISSN: 10837450     EISSN: 10979867     Source Type: Journal    
DOI: 10.3109/10837450903036163     Document Type: Article

References (9)

1. Langer R. Drug delivery and targeting. Nature 1998;392:5-10.
2. Hennink, WE, Nostrum CF. Novel crosslinking methods to design hydrogels. Adv Drug Deliv Rev 2002;54:13-36.
3. Liebert T, Hornig S, Hesse S, Heinze TJ. Effect of polyelectrolyte structural features on flocculation behavior: Cationic polysaccharides vs.synthetic polycations. Am Chem Soc 2005;127:10484-10485.
4. Esfand R, Tomalia DA. Poly(amidoamine) (PAMAM) dendrimers: From biomimicry to drug delivery and biomedical applications. Drug Discov Today 2001:6:427-436.
5. Akiyoshi K, Deguchi S, Moriguchi N, Yamaguchi S, Sunamoto J. Self-aggregates of hydrophobized polysaccharides in water - formation and characteristics of nanoparticles. Macromolecules 1993;26:3062-3068.
6. Stenekes RJH, Talsma H, Hennink WE. Formation of dextran hydrogels by crystallisation. Biomaterials 2001;22:1891-1898.
7. Maina NH, Tenkanen M, Maaheimo H, Juvonen R, Virkky L. NMR spectroscopic analysis of exopolysaccharides produced by Leuconostoc citreum and Weissella confusa. Carbohydrate Res 2008;343:1446-1455.
8. Melik DJH, Fogler S. Turbidimetric determination of particle-size distributions of colloidal. J Colloid Interface Sci 1983;92:161-180.
9. Burchard W. Structure formation by polysaccharides in concentrated solution. Biomacromolecules 2001;2:342-353.