Assembly and simple demonstration of a micropump installing PDMS-based thin membranes as flexible micro check valves

Journal of Biomedical Nanotechnology

Volumn 5, Issue 5, 2009, Pages 516-520

  Tanaka, Yo ^a   Sato, Kae ^a   Kitamori, Takehiko ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

Check valve; Flexible material; Microfluidic device; Micropump; PDMS

Indexed keywords

BIOCHEMICAL SYSTEMS; BIOMEDICAL FIELDS; CARDIOMYOCYTES; CHECK VALVES; CHEMICAL ENERGY; CHEMICAL PROCESS; CHEMICAL SYSTEMS; FABRICATION METHOD; FLEXIBLE MATERIALS; IMMUNE ASSAY; MICRO PUMP; MICRO-FLUIDIC DEVICES; NANO-FLUIDIC DEVICES; POLYDIMETHYLSILOXANE PDMS; PUMPING FLUIDS; THIN MEMBRANE;

FLUIDIC DEVICES; MICROCHANNELS; MICROFLUIDICS; POLYIMIDES; PUMPS; SILICONES;

VALVES (MECHANICAL);

DIMETICONE; POLYIMIDE;

ARTICLE; ENERGY; FLOW RATE; HEART MUSCLE CELL; HEART STROKE VOLUME; IMMUNOASSAY; MICROANALYSIS; MICROCHIP ANALYSIS; MICROFLUIDICS; NANOFABRICATION; OSCILLATION; PUMP;

DIMETHYLPOLYSILOXANES; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; INFUSION PUMPS; MATERIALS TESTING; MEMBRANES, ARTIFICIAL; MICRO-ELECTRICAL-MECHANICAL SYSTEMS; MICROFLUIDICS; MINIATURIZATION;

EID: 76749162878     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2009.1057     Document Type: Article

References (21)

1. G. M. Whitesides, The origins and the future of microfluidics. Nature 442, 368 (2006).
2. P. S. Dittrich, K. Tachikawa, and A. Manz, Micro total analysis systems. Latest advancements and trends. Anal. Chem. 78, 3887 (2006).
3. Y. Tanaka, K. Morishima, T. Shimizu, A. Kikuchi, M. Yamato, T. Okano, and T. Kitamori, Demonstration of a PDMS-based bio-microactuator using cultured cardiomyocytes to drive polymer micropillars. Lab Chip 6, 230 (2006).
4. Y. Tanaka, K. Sato, T. Shimizu, M. Yamato, T. Okano, and T. Kitamori, Biological cells on microchips: New technologies and applications. Biosens. Bioelectron. 23, 449 (2007).
5. Y. Tanaka, K. Morishima, T. Shimizu, A. Kikuchi, M. Yamato, T. Okano, and T. Kitamori, An actuated pump on-chip powered by cultured cardiomyocytes. Lab Chip 6, 362 (2006).
6. J. Park, I. C. Kim, J. Baek, M. Cha, J. Kim, S. Park, J. Lee, and B. Kim, Micro pumping with cardiomyocyte-polymer hybrid. Lab Chip 7, 1367 (2007).
7. J. Kim, J. Park, S. Yang, J. Baek, B. Kim, S. H. Lee, E. S. Yoon, K. Chun, and S. Park, Establishment of a fabrication method for a long-term actuated hybrid cell robot. Lab Chip 7, 1504 (2007).
8. J. Xi, J. J. Schmidt, and C. D. Montemagno, Self-assembled microdevices driven by muscle. Nat. Mater. 4, 180 (2005).
9. A. W. Feinberg, A. Feigel, S. S. Shevkoplyas, S. Sheehy, G. M. Whitesides, and K. K. Parker, Muscular thin films for building actuators and powering devices. Science 317, 1366 (2007).
10. M. Goto, K. Sato, A. Murakami, M. Tokeshi, and T. Kitamori, Development of a microchip-based bioassay system using cultured cells. Anal. Chem. 77, 2125 (2005).
11. H. Hisamoto, Y. Shimizu, K. Uchiyama, M. Tokeshi, Y. Kikutani, A. Hibara, and T. Kitamori, Chemicofunctional membrane for integrated chemical processes on a microchip. Anal. Chem. 75, 350 (2003).
12. K. Sato, M. Tokeshi, T. Odake, H. Kimura, T. Ooi, M. Nakao, and T. Kitamori, Integration of an immunosorbent assay system: Analysis of secretory human immunoglobulin a on polystyrenebeads in a microchip. Anal. Chem. 72, 1144 (2000).
13. N. Honda, S. Shoji, M. Isomura, Y. Ashihara, K. Akahori, and H. Sato, Fabrication of micro flow cell for multi-analyte sandwich immunoassay using Teflon micro check valves. Micro Total Analysis Systems 2001, edited by J. M. Ramsey and A. van den Berg, Kluwer Academic Publishers, Dordrecht (2001), Vol. 1, p. 403.
14. D. J. Laser and J. G. Santiago, A review of micropumps. J. Micromech. Microeng. 14, R35 (2004).
15. A. Tourovskaia, T. Barber, B. T. Wickes, D. Hirdes, B. Grin, D. G. Castner, K. E. Healy, and A. Folch, Micropatterns of chemisorbed cell adhesion-repellent films using oxygen plasma etching and elastomeric masks. Langmuir 19, 4754 (2003).
16. Y. N. Xia and G. M. Whitesides, Soft lithography. Angew. Chem. Int. Ed. 37, 550 (1998).
17. S. R. Quake and A. Scherer, From micro- to nanofabrication with soft materials. Science 290, 1536 (2000).
18. T. Thorsen, S. J. Maerkl, and S. R. Quake, Microfluidic large-scale integration. Science 298, 580 (2002).
19. J. S. Go and S. Shoji, A disposable, dead volume-free and leak-free in-plane PDMS microvalve. Sens. Actuators A, Physical 114, 438 (2004).
20. J. W. Song, W. Gu, N. Futai, K. A. Warner, J. E. Nor, and S. Takayama, Computer-controlled microcirculatory support system for endothelial cell culture and shearing. Anal. Chem. 77, 3993 (2005).
21. N. L. Jeon, D. T. Chiu, C. J. Wargo, H. Wu, I. S. Choi, J. R. Anderson, and G. M. Whitesides, Design and fabrication of integrated passive valves and pumps for flexible polymer 3-dimensional microfluidic systems. Biomed. Microdevices 4, 117 (2002).