c-Cbl mediated ubiquitylation and regulation of cell surface exposure of CD5

Biochemical and Biophysical Research Communications

Volumn 392, Issue 4, 2010, Pages 500-504

  Demydenko, Dmytro ^a  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

Author keywords

c Cbl; CD5; Receptor downregulation; Thymus; Ubiquitin

Indexed keywords

CBL PROTEIN; CD5 ANTIGEN; CELL SURFACE RECEPTOR; COMPLEMENTARY DNA; EPIDERMAL GROWTH FACTOR RECEPTOR; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MESSENGER RNA; UBIQUITIN;

ANIMAL CELL; ARTICLE; HUMAN; HUMAN CELL; INTERNALIZATION; LEUKEMIA CELL LINE; LYSOSOME; LYSOSOME MEMBRANE; MEMBRANE VESICLE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR DOWN REGULATION; THYMOCYTE; THYMUS;

ANIMALS; ANTIGENS, CD5; CELL MEMBRANE; DOWN-REGULATION; HUMANS; JURKAT CELLS; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS; LYSOSOMES; MICE; PROTO-ONCOGENE PROTEINS C-CBL; T-LYMPHOCYTES; UBIQUITINATION;

EID: 76749159729     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.01.052     Document Type: Article

References (14)

1. Hemler M.E., Brenner M.B., McLean J.M., and Strominger J.L. Antigenic stimulation regulates the level of expression of interleukin 2 receptor on human T cells. Proc. Natl. Acad. Sci. USA 81 (1984) 2172-2175
2. Swaminathan G., and Tsygankov A.Y. The Cbl family proteins: ring leaders in regulation of cell signaling. J. Cell. Physiol. 209 1 (2006) 21-43
3. Schmidt M.H., and Dikic I. The Cbl interactome and its functions. Nat. Rev. Mol. Cell Biol. 6 12 (2005) 907-918
4. Vera J., Fenutría R., Cañadas O., Figueras M., Mota R., Sarrias M.R., Williams D.L., Casals C., Yelamos J., and Lozano F. The CD5 ectodomain interacts with conserved fungal cell wall components and protects from zymosan-induced septic shock-like syndrome. Proc. Natl. Acad. Sci. USA 106 5 (2009) 1506-1511
5. Dennehy K.M., Broszeit R., Ferris W.F., and Beyers A.D. Thymocyte activation induces the association of the proto-oncoprotein c-cbl and ras GTPase-activating protein with CD5. Eur. J. Immunol. 28 5 (1998) 1617-1625
6. Naramura M., Kole H.K., Hu R.J., and Gu H. Altered thymic positive selection and intracellular signals in Cbl-deficient mice. Proc. Natl. Acad. Sci. USA 95 26 (1998) 15547-15552
7. Deckert M., Elly C., Altman A., and Liu Y.C. Coordinated regulation of the tyrosine phosphorylation of Cbl by Fyn and Syk tyrosine kinases. J. Biol. Chem. 273 (1998) 8867-8874
8. Qiu L., Joazeiro C., Fang N., Wang H.Y., Elly C., Altman Y., Fang D., Hunter T., and Liu Y.C. Recognition and ubiquitylation of Notch by Itch, a hect-type E3 ubiquitin ligase. J. Biol. Chem. 275 (2000) 35734-35737
9. Northrop J.P., Ullman K.S., and Crabtree G.R. Characterization of the nuclear and cytoplasmic components of the lymphoid-specific nuclear factor of activated T cells (NF-AT) complex. J. Biol. Chem. 268 (1993) 2917-2923
10. Eskelinen E.L. Roles of LAMP-1 and LAMP-2 in lysosome biogenesis and autophagy. Mol. Aspects Med. 27 5-6 (2006) 495-502
11. Liu Y.C. Ubiquitin ligases and the immune response. Annu. Rev. Immunol. 22 (2004) 81-127
12. Sorkin A., and Goh L.K. Endocytosis and intracellular trafficking of ErbBs. Exp. Cell Res. 315 4 (2009) 683-696
13. Kassenbrock C.K., and Anderson S.M. Regulation of ubiquitin protein ligase activity in c-Cbl by phosphorylation-induced conformational change and constitutive activation by tyrosine to glutamate point mutations. J. Biol. Chem. 279 27 (2004) 28017-28027
14. Caron G., Duluc D., Frémaux I., Jeannin P., David C., Gascan H., and Delneste Y. Direct stimulation of human T cells via TLR5 and TLR7/8: Flagellin and R-848 up-regulate proliferation and IFN-gamma production by memory CD4+ T cells. J. Immunol. 175 (2005) 1551-1557