Inhibition of tumorigenicity and enhancement of radiochemosensitivity in head and neck squamous cell cancer-derived ALDH1-positive cells by knockdown of Bmi-1

Oral Oncology

Volumn 46, Issue 3, 2010, Pages 158-165

  Chen, Yu Chih ^a,b   Chang, Charn Jung ^c,d   Hsu, Han Shui ^a,b   Chen, Yi Wei ^a,b   Tai, Lung Kuo ^a,b   Tseng, Ling Ming ^a,b   Chiou, Guang Yuh ^a,b   Chang, Shih Ching ^a,b   Kao, Shou Yen ^a,b   Chiou, Shih Hwa ^a,b   Lo, Wen Liang ^a,b  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^d Pharmaceutical Management Division

Author keywords

ALDH1; Bmi 1; Cancer stem cells; Head and neck squamous cell carcinoma (HNSCC)

Indexed keywords

ALDEHYDE DEHYDROGENASE ISOENZYME 1; BMI1 PROTEIN; OXIDOREDUCTASE; PACLITAXEL; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER RADIOTHERAPY; CARCINOGENICITY; CHEMOSENSITIVITY; CONTROLLED STUDY; HEAD AND NECK CANCER; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOSENSITIVITY; SQUAMOUS CELL CARCINOMA;

AGED; ALDEHYDE DEHYDROGENASE; ANIMALS; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; FEMALE; GENE KNOCKDOWN TECHNIQUES; HEAD AND NECK NEOPLASMS; HUMANS; ISOENZYMES; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; MIDDLE AGED; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL;

EID: 76749158386     PISSN: 13688375     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2009.11.007     Document Type: Article

References (29)

1. Kamangar F., Dores G.M., and Anderson W.F. Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world. J Clin Oncol 24 (2006) 2137-2150
2. Khawaja M.R., Mazahir S., Majeed A., Malik F., Merchant K.A., Maqsood M., et al. Chewing of betel, areca and tobacco: perceptions and knowledge regarding their role in head and neck cancers in an urban squatter settlement in Pakistan. Asian Pac J Cancer Prev 7 (2006) 95-100
3. Lo W.L., Kao S.Y., Chi L.Y., Wong Y.K., and Chang R.C. Outcomes of oral squamous cell carcinoma in Taiwan after surgical therapy: factors affecting survival. J Oral Maxillofac Surg 61 (2003) 751-758
4. Molofsky A.V., Pardal R., Iwashita T., Park I.K., Clarke M.F., and Morrison S.J. Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 425 (2003) 962-967
5. Park I.K., Qian D., Kiel M., Becker M.W., Pihalja M., Weissman I.L., et al. Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature 423 (2003) 302-305
6. Sangiorgi E., and Capecchi M.R. Bmi1 is expressed in vivo in intestinal stem cells. Nat Genet 40 (2008) 915-920
7. Haupt Y., Alexander W.S., Barri G., Klinken S.P., and Adams J.M. Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E mu-myc transgenic mice. Cell 65 (1991) 753-763
8. Jacobs J.J., Scheijen B., Voncken J.W., Kieboom K., Berns A., and van Lohuizen M. Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF. Genes Dev 13 (1999) 2678-2690
9. Qin Z.K., Yang J.A., Ye Y.L., Zhang X., Xu L.H., Zhou F.J., et al. Expression of Bmi-1 is a prognostic marker in bladder cancer. BMC Cancer 9 (2009) 61
10. Cooper C.S., and Foster C.S. Concepts of epigenetics in prostate cancer development. Br J Cancer 100 (2009) 240-245
11. Tirabosco R., De Maglio G., Skrap M., Falconieri G., and Pizzolitto S. Expression of the Polycomb-group protein BMI1 and correlation with p16 in astrocytomas an immunohistochemical study on 80 cases. Pathol Res Pract 204 (2008) 625-631
12. Hayry V., Tynninen O., Haapasalo H.K., Wolfer J., Paulus W., Hasselblatt M., et al. Stem cell protein BMI-1 is an independent marker for poor prognosis in oligodendroglial tumours. Neuropathol Appl Neurobiol 34 (2008) 555-563
13. Arnes J.B., Collett K., and Akslen L.A. Independent prognostic value of the basal-like phenotype of breast cancer and associations with EGFR and candidate stem cell marker BMI-1. Histopathology 52 (2008) 370-380
14. Vrzalikova K., Skarda J., Ehrmann J., Murray P.G., Fridman E., Kopolovic J., et al. Prognostic value of Bmi-1 oncoprotein expression in NSCLC patients: a tissue microarray study. J Cancer Res Clin Oncol 134 (2008) 1037-1042
15. Sparmann A., and van Lohuizen M. Polycomb silencers control cell fate, development and cancer. Nat Rev Cancer 6 (2006) 846-856
16. Jordan C.T., Guzman M.L., and Noble M. Cancer stem cells. N Engl J Med 355 (2006) 1253-1261
17. Prince M.E., Sivanandan R., Kaczorowski A., Wolf G.T., Kaplan M.J., Dalerba P., et al. Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. Proc Natl Acad Sci USA 104 (2007) 973-978
18. Okamoto A., Chikamatsu K., Sakakura K., Hatsushika K., Takahashi G., and Masuyama K. Expansion and characterization of cancer stem-like cells in squamous cell carcinoma of the head and neck. Oral Oncol 45 (2009) 633-639
19. Chen Y.C., Chen Y.W., Hsu H.S., Tseng L.M., Huang P.I., Lu K.H., Chen D.T., Tai L.K., Yung M.C., Chang S.C., Ku H.H., Chiou S.H., et al. Aldehyde dehydrogenase 1 is a putative marker for cancer stem cells in head and neck squamous cancer. Biochem Biophys Res Commun 385 (2009) 307-313
20. Zhang P., Zhang Y., Mao L., Zhang Z., and Chen W. Side population in oral squamous cell carcinoma possesses tumor stem cell phenotypes. Cancer Lett 277 (2009) 227-234
21. Chiou S.H., Kao C.L., Chen Y.W., Chien C.S., Hung S.C., Lo J.F., et al. Identification of CD133-positive radioresistant cells in atypical teratoid/rhabdoid tumor. PLoS ONE 3 (2008) e2090
22. Boiani M., and Scholer H.R. Regulatory networks in embryo-derived pluripotent stem cells. Nat Rev Mol Cell Biol 6 (2005) 872-884
23. Iwama A., Oguro H., Negishi M., Kato Y., Morita Y., Tsukui H., et al. Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1. Immunity 21 (2004) 843-851
24. Jiang L., Li J., and Song L. Bmi-1, stem cells and cancer. Acta Biochim Biophys Sin (Shanghai) 41 (2009) 527-534
25. Godlewski J., Nowicki M.O., Bronisz A., Williams S., Otsuki A., Nuovo G., et al. Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal. Cancer Res 68 (2008) 9125-9130
26. Yang J., Chai L., Liu F., Fink L.M., Lin P., Silberstein L.E., et al. Bmi-1 is a target gene for SALL4 in hematopoietic and leukemic cells. Proc Natl Acad Sci USA 104 (2007) 10494-10499
27. Stupp R., Mason W.P., van den Bent M.J., Weller M., Fisher B., Taphoorn M.J., Belanger K., Brandes A.A., Marosi C., Bogdahn U., Curschmann J., Janzer R.C., et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352 (2005) 987-996
28. Lee C.J., Dosch J., and Simeone D.M. Pancreatic cancer stem cells. J Clin Oncol 26 (2008) 2806-2812
29. Vormittag L., Thurnher D., Geleff S., Pammer J., Heiduschka G., Brunner M., et al. Co-expression of Bmi-1 and podoplanin predicts overall survival in patients with squamous cell carcinoma of the head and neck treated with radio(chemo)therapy. Int J Radiat Oncol Biol Phys 73 (2009) 913-918