Improvement of water solubility and in vitro dissolution rate of aceclofenac by complexation with β-cyclodextrin and hydroxypropyl-β- cyclodextrin

Pharmaceutical Development and Technology

Volumn 15, Issue 1, 2010, Pages 64-70

  Ranpise, Nisharani S ^a   Kulkarni, Nilesh S ^a   Mair, Parth D ^a   Ranade, Arati N ^a  

^a SINHGAD COLLEGE OF PHARMACY   (India)

Author keywords

Aceclofenac; Cyclodextrin; Inclusion complexes; Spray drying technique

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; ACECLOFENAC; 2-HYDROXYPROPYL-BETA-CYCLODEXTRIN; BETA CYCLODEXTRIN; BETA CYCLODEXTRIN DERIVATIVE; DICLOFENAC; NONSTEROID ANTIINFLAMMATORY AGENT; WATER;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG SOLUBILITY; INFRARED SPECTROSCOPY; MICROWAVE IRRADIATION; MOUSE; NONHUMAN; PAW EDEMA; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; SPRAY DRYING; SUSPENSION; WRITHING TEST; X RAY POWDER DIFFRACTION; ANALOGS AND DERIVATIVES; ANIMAL; CHEMISTRY; MEDICINAL CHEMISTRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POWDER DIFFRACTION; SOLUBILITY;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BETA-CYCLODEXTRINS; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; DICLOFENAC; MAGNETIC RESONANCE SPECTROSCOPY; MICE; POWDER DIFFRACTION; RATS; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; WATER;

EID: 76749145973     PISSN: 10837450     EISSN: 10979867     Source Type: Journal    
DOI: 10.3109/10837450903002165     Document Type: Article

References (10)