Surfactant Protein A2 Polymorphisms and Disease Severity in a Respiratory Syncytial Virus-Infected Population

Journal of Pediatrics

Volumn 156, Issue 3, 2010, Pages

  El Saleeby, Chadi M ^a,b,c,d,e   Li, Rongling ^b   Somes, Grant W ^b   Dahmer, Mary K ^f   Quasney, Michael W ^f   DeVincenzo, John P ^b,c,d,g  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF TENNESSEE COLLEGE OF MEDICINE   (United States)

^c LE BONHEUR CHILDREN S HOSPITAL   (United States)

^d LE BONHEUR CHILDREN'S MEDICAL CENTER   (United States)

^e ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^f MEDICAL COLLEGE OF WISCONSIN   (United States)

^g UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ARTICLE; DISEASE SEVERITY; DNA POLYMORPHISM; ETHNIC DIFFERENCE; FEMALE; GENE; GENETIC ASSOCIATION; GENETIC VARIABILITY; HETEROZYGOSITY; HOMOZYGOSITY; HOSPITALIZATION; HUMAN; INFANT; MALE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; SURFACTANT PROTEIN A2 GENE; VIRUS INFECTION;

EID: 76749141245     PISSN: 00223476     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpeds.2009.09.043     Document Type: Article

References (33)

1. Glezen W.P., Taber L.H., Frank A.L., and Kasel J.A. Risk of primary infection and reinfection with respiratory syncytial virus. Am J Dis Child 140 (1986) 543-546
2. Boyce T.G., Mellen B.G., Mitchel Jr. E.F., Wright P.F., and Griffin M.R. Rates of hospitalization for respiratory syncytial virus infection among children in medicaid. J Pediatr 137 (2000) 865-870
3. Wang E.E., Law B.J., and Stephens D. Pediatric Investigators Collaborative Network on Infections in Canada (PICNIC) prospective study of risk factors and outcomes in patients hospitalized with respiratory syncytial viral lower respiratory tract infection. J Pediatr 126 (1995) 212-219
4. Van Iwaarden J.F., Pikaar J.C., Storm J., Brouwer E., Verhoef J., Oosting R.S., et al. Binding of surfactant protein A to the lipid A moiety of bacterial lipopolysaccharides. Biochem J 303 Pt 2 (1994) 407-411
5. Ohmer-Schrock D., Schlatterer C., Plattner H., and Schlepper-Schafer J. Lung surfactant protein A (SP-A) activates a phosphoinositide/calcium signaling pathway in alveolar macrophages. J Cell Sci 108 Pt 12 (1995) 3695-3702
6. Tino M.J., and Wright J.R. Surfactant protein A stimulates phagocytosis of specific pulmonary pathogens by alveolar macrophages. Am J Physiol 270 (1996) L677-L688
7. Ghildyal R., Hartley C., Varrasso A., Meanger J., Voelker D.R., Anders E.M., et al. Surfactant protein A binds to the fusion glycoprotein of respiratory syncytial virus and neutralizes virion infectivity. J Infect Dis 180 (1999) 2009-2013
8. LeVine A.M., Gwozdz J., Stark J., Bruno M., Whitsett J., and Korfhagen T. Surfactant protein-A enhances respiratory syncytial virus clearance in vivo. J Clin Invest 103 (1999) 1015-1021
9. Kerr M.H., and Paton J.Y. Surfactant protein levels in severe respiratory syncytial virus infection. Am J Respir Crit Care Med 159 (1999) 1115-1118
10. Barr F.E., Pedigo H., Johnson T.R., and Shepherd V.L. Surfactant protein-A enhances uptake of respiratory syncytial virus by monocytes and U937 macrophages. Am J Respir Cell Mol Biol 23 (2000) 586-592
11. Floros J., DiAngelo S., Koptides M., Karinch A.M., Rogan P.K., Nielsen H., et al. Human SP-A locus: allele frequencies and linkage disequilibrium between the two surfactant protein A genes. Am J Respir Cell Mol Biol 15 (1996) 489-498
12. Liu W., Bentley C.M., and Floros J. Study of human SP-A, SP-B and SP-D loci: allele frequencies, linkage disequilibrium and heterozygosity in different races and ethnic groups. BMC Genet 4 (2003) 13
13. Kala P., Ten Have T., Nielsen H., Dunn M., and Floros J. Association of pulmonary surfactant protein A (SP-A) gene and respiratory distress syndrome: interaction with SP-B. Pediatr Res 43 (1998) 169-177
14. Ramet M., Lofgren J., Alho O.P., and Hallman M. Surfactant protein-A gene locus associated with recurrent otitis media. J Pediatr 138 (2001) 266-268
15. Pettigrew M.M., Gent J.F., Zhu Y., Triche E.W., Belanger K.D., Holford T.R., et al. Association of surfactant protein A polymorphisms with otitis media in infants at risk for asthma. BMC Med Genet 7 (2006) 68
16. Lofgren J., Ramet M., Renko M., Marttila R., and Hallman M. Association between surfactant protein A gene locus and severe respiratory syncytial virus infection in infants. J Infect Dis 185 (2002) 283-289
17. Devincenzo J.P. Natural infection of infants with respiratory syncytial virus subgroups A and B: a study of frequency, disease severity, and viral load. Pediatr Res 56 (2004) 914-917
18. DiAngelo S., Lin Z., Wang G., Phillips S., Ramet M., Luo J., et al. Novel, non-radioactive, simple and multiplex PCR-cRFLP methods for genotyping human SP-A and SP-D marker alleles. Dis Markers 15 (1999) 269-281
19. US census bureau online. Available at: http://quickfacts.census.gov/qfd/states. Accessed July 15, 2009.
20. DeVincenzo J.P. Factors predicting childhood respiratory syncytial virus severity: what they indicate about pathogenesis. Pediatr Infect Dis J 24 (2005) S177-S183
21. DeVincenzo J.P. A new direction in understanding the pathogenesis of respiratory syncytial virus bronchiolitis: how real infants suffer. J Infect Dis 195 (2007) 1084-1086
22. Miyairi I., and DeVincenzo J.P. Human genetic factors and respiratory syncytial virus disease severity. Clin Microbiol Rev 21 (2008) 686-703
23. Lahti M., Lofgren J., Marttila R., Renko M., Klaavuniemi T., Haataja R., et al. Surfactant protein D gene polymorphism associated with severe respiratory syncytial virus infection. Pediatr Res 51 (2002) 696-699
24. Amanatidou V., Sourvinos G., Apostolakis S., Neonaki P., Tsilimigaki A., Krambovitis E., et al. RANTES promoter gene polymorphisms and susceptibility to severe respiratory syncytial virus-induced bronchiolitis. Pediatr Infect Dis J 27 (2008) 38-42
25. Amanatidou V., Sourvinos G., Apostolakis S., Tsilimigaki A., and Spandidos D.A. T280M variation of the CX3C receptor gene is associated with increased risk for severe respiratory syncytial virus bronchiolitis. Pediatr Infect Dis J 25 (2006) 410-414
26. Awomoyi A.A., Rallabhandi P., Pollin T.I., Lorenz E., Sztein M.B., Boukhvalova M.S., et al. Association of TLR4 polymorphisms with symptomatic respiratory syncytial virus infection in high-risk infants and young children. J Immunol 179 (2007) 3171-3177
27. Wilson J., Rowlands K., Rockett K., Moore C., Lockhart E., Sharland M., et al. Genetic variation at the IL10 gene locus is associated with severity of respiratory syncytial virus bronchiolitis. J Infect Dis 191 (2005) 1705-1709
28. Puthothu B., Krueger M., Forster J., Heinze J., Weckmann M., and Heinzmann A. Interleukin (IL)-18 polymorphism 133C/G is associated with severe respiratory syncytial virus infection. Pediatr Infect Dis J 26 (2007) 1094-1098
29. Janssen R., Bont L., Siezen C.L., Hodemaekers H.M., Ermers M.J., Doornbos G., et al. Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes. J Infect Dis 196 (2007) 826-834
30. Wang G., Phelps D.S., Umstead T.M., and Floros J. Human SP-A protein variants derived from one or both genes stimulate TNF-alpha production in the THP-1 cell line. Am J Physiol Lung Cell Mol Physiol 278 (2000) L946-L954
31. Thomas N.J., Diangelo S., Hess J.C., Fan R., Ball M.W., Geskey J.M., et al. Transmission of Surfactant Protein Variants and Haplotypes in Children Hospitalized with Respiratory Syncytial Virus. Pediatr Res 66 (2009) 70-73
32. Ramensky V., Bork P., and Sunyaev S. Human non-synonymous SNPs: server and survey. Nucleic Acids Res 30 (2002) 3894-3900
33. DeVincenzo J.P., El Saleeby C.M., and Bush A.J. Respiratory syncytial virus load predicts disease severity in previously healthy infants. J Infect Dis 191 (2005) 1861-1868