Perfusion by magnetic resonance imaging: Its physical foundations and clinical application;Perfusión por resonancia magnética: Bases físicas y aplicación clínica

Revista de Neurologia

Volumn 50, Issue 1, 2010, Pages 23-32

  Fayed Miguel, Nicolás ^a   Castillo Blandino, Julio ^b   Medrano Lin, Jaime ^a  

^a HOSPITAL QUIRÓN   (Spain)

^b Hospital Bautista   (Nicaragua)

Author keywords

Central nervous system diseases; Magnetic resonance imaging; Pathophysiology; Perfusion

Indexed keywords

BRAIN BLOOD FLOW; BRAIN DEGENERATION; BRAIN ISCHEMIA; BRAIN METASTASIS; BRAIN TUMOR; CAPILLARY PERMEABILITY; ENCEPHALITIS; EPILEPSY; FIRST PASS EFFECT; FOLLOW UP; GLIOMA; HUMAN; LYMPHOMA; MENINGIOMA; MIGRAINE; MULTIPLE SCLEROSIS; NEURINOMA; OLIGODENDROGLIOMA; PERFUSION WEIGHTED IMAGING; POSITRON EMISSION TOMOGRAPHY; RADIATION NECROSIS; REVIEW; SCHIZOPHRENIA; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; T1 WEIGHTED DYNAMIC CONTRAST ENHANCEMENT IMAGING; T2 WEIGHTED DYNAMIC SUSCEPTIBILITY CONTRAST MAGNETIC RESONANCE IMAGING; TOXOPLASMOSIS;

EID: 76749122329     PISSN: 02100010     EISSN: None     Source Type: Journal    
DOI: 10.33588/rn.5001.2008363     Document Type: Review

References (76)

1. Alsop DC. Imagen de RM de perfusión. In Scott W, ed Atlas. Magnetic resonance imaging of the brain and spine. 3 ed. Spanish edition. Madrid: Marban; 2004. p. 215-37.
2. Gili J. Técnicas especiales en IRM. In: Introducción biofísica a la resonancia magnética en neuroimagen. Barcelona: Centre Diagnòstic Pedralbes; 1993. p. 21-8.
3. D'Arcy JA, Collins DJ, Padhani AR. Informatics in radiology (infoRAD): magnetic resonance imaging workbench: analysis and visualization of dynamic contrast-enhanced MR imaging data. Radiographics 2006; 26: 621-32.
4. Aksoy FG, Lev MH. Dynamic contrast-enhanced brain perfusion imaging: technique and clinical applications. Semin Ultrasound CT MR 2000; 21: 462-77.
5. Barbier EL, Lamalle L, Decorps M. Methodology of brain perfusion imaging. J Magn Reson Imaging 2001; 13: 496-520.
6. Provenzale JM, Mukundan S, Barboriak DP. Diffusion-weighted and perfusion MR imaging for brain tumor characterization and assessment of treatment response. Radiology 2006; 239: 632-49.
7. Roberts G, Larson K. The interpretation of mean transit time measurements for multi-phase tissue systems. J Theor Biol 1973; 39: 447-75.
8. Kassner A, Annesley DJ, Zhu XP, Li KL, Kamaly-Asl ID, Watson Y, et al. Abnormalities of the contrast re-circulation phase in cerebral tumors demonstrated using dynamic susceptibility contrast-enhanced imaging: a possible marker of vascular tortuosity. J Magn Reson Imaging 2000; 11: 103-13.
9. Cha S, Knopp EA, Johnson G, Wetzel SG, Litt AW, Zagzag D. Intracranial mass lesions: dynamic contrast-enhanced susceptibility-weighted echo-planar perfusion MR imaging. Radiology 2002; 223: 11-29.
10. Barbier EL, Lamalle L, Decorps M. Methodology of brain perfusion imaging. J Magn Reson Imaging 2001; 13: 496-520.
11. Meier P, Zierler K. On the theory of the indicator-dilution method for measurement of blood flow and volume. J Appl Physiol 1954; 6: 731-744.
12. Cha S. Update of brain tumor imaging: from anatomy to physiology. AJNR Am J Neuroradiol 2006; 27: 475-87.
13. Jackson A. Perfusion MR imaging in adult neoplasia. In Gillard J, Waldman A, Barker P, eds. Clinical MR neuroimaging: diffusion, perfusion and spectroscopy. 1 ed. Cambridge: Cambridge University Press; 2005. p. 329-44.
14. Tress MB. Cerebrovascular disease: overview. In Gillard J, Waldman A, Barker P, eds. Clinical MR neuroimaging: diffusion, perfusion and spectroscopy. 1 ed. Cambridge: Cambridge University Press; 2005. p. 163-166.
15. National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group T. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med 1995; 333: 1581-7.
16. González RG. Imaging-guided acute ischemic stroke therapy: from 'time is brain' to 'physiology is brain'. AJNR Am J Neuroradiol 2006; 27: 728-35.
17. Karonen JO, Liu Y, Vanninen RL, Ostergaard L, Kaarina-Partanen PL, Vainio PA, et al. Combined perfusion- and diffusion-weighted MR imaging in acute ischemic stroke during the 1st week: a longitudinal study. Radiology 2000; 217: 886-94.
18. Powers WJ, Grubb RL Jr, Darriet D, Raichle ME. Cerebral blood flow and cerebral metabolic rate of oxygen requirements for cerebral function and viability in humans. J Cereb Blood Flow Metab 1985; 5: 600-8.
19. Baron JC. Perfusion thresholds in human cerebral ischemia: historical perspective and therapeutic implications. Cerebrovasc Dis 2001; 11 (Suppl 1): S2-8.
20. Sorensen AG, Buonanno FS, González RG, Schwamm LH, Lev MH, Huang-Hellinger FR, et al. Hyperacute stroke: evaluation with combined multisection diffusion-weighted and hemodynamically weighted echo-planar MR imaging. Radiology 1996; 199: 391-401.
21. Kidwell CS, Saver JL, Starkman S, Duckwiler G, Jahan R, Vespa P, et al. Late secondary ischemic injury in patients receiving intraarterial thrombolysis. Ann Neurol 2002; 52: 698-703.
22. Karonen JO, Vanninen RL, Liu Y, Ostergaard L, Kuikka JT, Nuutinen J, et al. Combined diffusion and perfusion MRI with correlation to single-photon emission CT in acute ischemic stroke. Ischemic penumbra predicts infarct growth. Stroke 1999; 30: 1583-90.
23. Ueda T, Yuh WT, Maley JE, Quets JP, Hahn PY, Magnotta VA. Outcome of acute ischemic lesions evaluated by diffusion and perfusion MR imaging. AJNR Am J Neuroradiol 1999; 20: 983-9.
24. Grandin CB, Duprez TP, Smith AM, Mataigne F, Peeters A, Oppenheim C, et al. Which MR-derived perfusion parameters are the best predictors of infarct growth in hyperacute stroke? Comparative study between relative and quantitative measurements. Radiology 2002; 223: 361-70.
25. Shih LC, Saver JL, Alger JR, Starkman S, Leary MC, Vinuela F, et al. Perfusion-weighted magnetic resonance imaging thresholds identifying core, irreversibly infracted tissue. Stroke 2003; 34: 1425-30.
26. Schaefer PW, Ozsunar Y, He J, Hamberg LM, Hunter GJ, Sorensen AG, et al. Assessing tissue viability with MR diffusion and perfusion imaging. AJNR Am J Neuroradiol 2003; 24: 436-43.
27. Neumann-Haefelin T, Wittsack HJ, Wenserski F, Siebler M, Seitz RJ, Modder U, et al. Diffusion- and perfusion-weighted MRI. The DWI/PWI mismatch region in acute stroke. Stroke 1999; 30: 1591-7.
28. Rosen BR, Belliveau JW, Vevea JM, Brady TJ. Perfusion imaging with NMR contrast agents. Magn Reson Med 1990; 14: 249-65.
29. Ueda T, Sakaki S, Yuh WT, Nochide I, Ohta S. Outcome in acute stroke with successful intra-arterial thrombolysis and predictive value of initial single-photon emission-computed tomography. J Cereb Blood Flow Metab 1999; 19: 99-108.
30. Wardlaw JM. Diffusion and perfusion MR in stroke. In Gaillard J, Waldman A, Barker P, eds. Clinical MR neuroimaging: diffusion, perfusion and spectroscopy. 1 ed. Cambridge: Cambridge University Press; 2005. p. 192-6.
31. Tsuchida C, Yamada H, Maeda M, Sadato N, Matsuda T, Kawamura Y, et al. Evaluation of peri-infarcted hypoperfusion with T2*-weighted dynamic MRI. J Magn Reson Imaging 1997; 7: 518-22.
32. Kassner A, Roberts T, Taylor K, Silver F, Mikulis D. Prediction of hemorraghe in acute ischemic stroke using permeability MR imaging. AJNR Am J Neuroradiol 2005; 26: 2213-7.
33. Guckel FJ, Brix G, Schmiedek P, Piepgras Z, Becker G, Kopke J, et al. Cerebrovascular reserve capacity in patients with occlusive cerebrovascular disease: assessment with dynamic susceptibility contrast-enhanced MR imaging and the acetazolamide stimulation test. Radiology 1996; 201: 405-12.
34. Duyn JH, Van Gelderen P, Barker P, Frank JA, Mattay VS, Moonen CT. 3D bolus tracking with frequency-shifted BURST MRI. J Comput Assist Tomogr 1994; 18: 680-7.
35. Fayed N, Morales H, Modrego P. Resonancia magnética con espectroscopia, perfusión y difusión cerebral en el diagnóstico de los tumores cerebrales. Rev Neurol 2006; 42: 735-42.
36. Folkman J. New perspectives in clinical oncology from angiogenesis research. Eur J Cancer 1996; 32A: 2534-9.
37. Tofts PS, Kermode AG. Measurement of the blood-brain barrier permeability and leakage space using dynamic MR imaging. 1. Fundamental concepts. Magn Reson Med 1991; 17: 357-67.
38. Weisskoff RM, Boxerman JL, Sorensen AG, Kulke SM, Campbell TA, Rosen BR. Simultaneous blood volume and permeability mapping using a single GD-based contrast injection. Proceedings of the First Meeting of the Society of Magnetic Resonance. Berkeley: Society of Magnetic Resonance; 1994. p. 279.
39. Cha S. Perfusion MR imaging of brain tumors. Top Magn Reson Imaging 2004; 15: 279-89.
40. Siegal T, Rubinstein R, Tzuk-Shima T, Gomori J. M. Utility of relative cerebral blood volume mapping derived from perfusion magnetic resonance imaging in the routine follow up of brain tumors. J Neurosurg 1997; 6: 22-7.
41. Knopp EA, Cha S, Johnson G, Mazumdar A, Golfinos JG, Zagzag D, et al. Glial neoplasms: dynamic contrast-enhanced T2*-weighted MR imaging. Radiology 1999; 211: 791-8.
42. Fayed N, Dávila J, Medrano J, Olmos S. Malignancy assessment of brain tumours with magnetic resonance spectroscopy and dynamic susceptibility contrast MRI. Eur J Radiol 2008; 67: 427-33.
43. Martin AJ, Cha S, Higashida RT, Cullen SP, Halbach V, Dowd CF, et al. Assessment of vasculature of meningiomas and the effects of embolization with intra-arterial MR perfusion imaging: a feasibility study. AJNR Am J Neuroradiol 2007; 28: 1771-7.
44. Cha S, Knopp EA, Johnson G, Wetzel S, Litt A, Zagzag D. Intracranial mass lesions: dynamic contrast-enhanced susceptibility-weighted echo-planar perfusion MR imaging. Radiology 2002; 223: 11-29.
45. Ernst T, Chang L, Witt M, Aronow H, Cornford M, Walot I, et al. Cerebral toxoplasmosis and lymphoma in AIDS: perfusion MR imaging experience in 13 patients. Radiology 1998; 208: 663-9.
46. Erdogan C, Hakyemez B, Yildirim N, Parlak M. Brain abscess and cystic brain tumor: discrimination with dynamic susceptibility contrast perfusion-weighted MRI. J Comput Assist Tomogr 2005; 29: 663-7.
47. Sugahara T, Korigi Y, Tomguchi S, Shigematus Y, Ikushima I, Kira T, et al. Postherapeutic intraaxial brain tumor: the value of perfusion-sensitive contrast-enhanced MR imaging for differentiating tumor recurrence from nonneoplastic contrast-enhancing tissue. AJNR Am J Neuroradiol 2000; 21: 901-9.
48. Zhu XP, Li KL, Kamaly-Asl ID, Checkley DR, Tessier JJ, Waterton JC, et al. Quantification of endothelial permeability, leakage space, and blood volume in brain tumors using combined T1 and T2* contrast-enhanced dynamic MR imaging. J Magn Reson Imaging 2000; 11: 575-85.
49. Arfanakis K, Hermann BP. Diffusion and perfusion MR imaging in seizure disorders. In Gaillard J, Waldman A, Barker P, eds. Clinical MR neuroimaging: diffusion, perfusion and spectroscopy. 1 ed. Cambridge: Cambridge University Press; 2005. p. 509-16.
50. Imperio W. Cerebral blood flow differs in adults with ADHD. Clin Psychiatry News 2000; 1: 10.
51. Kim BN, Lee JS, Shin MS, Cho SC, Lee DS. Regional cerebral perfusion abnormalities in attention deficit/hyperactivity disorder. Statistical parametric mapping analysis. Eur Arch Psychiatry Clin Neurosci 2002; 252: 219-25.
52. Cohen BM, Yurgelun TD, English CD, Renshaw P. Abnormalities of regional distribution of cerebral vasculature in schizophrenia detected by dynamic susceptibility contrast MRI. Am J Psychiatry 1995; 152: 1801-3.
53. Suzuki M, Nohara S, Hagino H, Takahashi T, Kawasaki Y, Yamashita I, et al. Prefrontal abnormalities in patients with simple schizophrenia: structural and functional brain-imaging studies in five cases. Psychiatry Res 2005; 140: 157-71.
54. Tsushima Y, Endo K. MR Imaging in the evaluation of chronic or recurrent headache. Radiology 2005; 235: 575-9.
55. De Benedittis G, Ferrari Da Passano C, Granata G, Lorenzetti A. CBF changes during headache-free periods and spontaneous/induced attacks in migraine with and without aura: a TCD and SPECT comparison study. J Neurosurg Sci 1999; 43: 141-6.
56. Sánchez del Río M, Bakker D, Wu O, Agosti R, Mitsikostas DD, Ostergaard L, et al. Perfusion weighted imaging during migraine: spontaneous visual aura and headache. Cephalalgia 1999; 19: 701-7.
57. Jager HR, Giffin NJ, Goadsby PJ. Diffusion- and perfusion-weighted MR imaging in persistent migrainous visual disturbances. Cephalalgia 2005; 25: 323-32.
58. Putnam TJ. The pathogenesis of multiple sclerosis: a possible vascular factor. N Engl J Med 1933; 209: 786-90.
59. Dawson JW. The histology of disseminated sclerosis. Transactions of the Royal Society of Edinburgh 1916; 50: 517-740.
60. Tanaka R, Iwasaki Y, Koprowski H. Ultrastructural studies of perivascular cuffing cells in multiple sclerosis brain. Am J Pathol 1975; 81: 467-78.
61. Ge Y, Law M, Johnson G, Herbert J, Babb JS, Lois J, et al. Dynamic susceptibility contrast perfusion MR imaging of multiple sclerosis lesions: characterizing hemodynamic impairment and inflammatory activity. AJNR Am J Neuroradiol 2005; 26: 1539-47.
62. Cha S, Pierce S, Knopp EA, Johnson G, Yang C, Ton A, et al. Dynamic contrast-enhanced T2*-weighted MR imaging of tumefactive demyelinating lesions. AJNR Am J Neuroradiol 2001; 22: 1109-16.
63. Brun A, Englund E. Regional pattern of degeneration in Alzheimer's disease: neuronal loss and histopathological grading. Histopathology 1981; 5: 549-64.
64. Modrego PJ, Fayed N, Pina MA. Conversion from mild cognitive impairment to probable Alzheimer's disease predicted by brain magnetic resonance spectroscopy. Am J Psychiatry 2005; 162: 667-75.
65. Modrego PJ, Pina MA, Fayed N, Díaz M. Changes in metabolite ratios after treatment with rivastigmine in Alzheimer's disease: a nonrandomised controlled trial with magnetic resonance spectroscopy. CNS Drugs 2006; 20: 867-77.
66. Renshaw PF, Levin JM, Kaufman MJ, Ross MH, Lewis RF, Harris GJ. Dynamic susceptibility contrast magnetic resonance imaging in neuropsychiatry: present utility and future promise. Eur Radiol 1997; 7: 216-21.
67. Harris GJ, Lewis RF, Satlin A, English CD, Scott TM, Yurgelun-Todd DA, et al. Dynamic susceptibility contrast MR imaging of regional cerebral blood volume in Alzheimer disease: a promising alternative to nuclear medicine. AJNR Am J Neuroradiol 1998; 19: 1727-32.
68. Bozzao A, Floris R, Baviera ME, Apruzzese A, Simonetti G. Diffusion and perfusion MR imaging in cases of Alzheimer's disease: correlations with cortical atrophy and lesion load. AJNR Am J Neuroradiol 2001; 22: 1030-6.
69. Johnson NA, Jahng GH, Weiner MW, Miller BL, Chui HC, Jagust WJ, et al. Pattern of cerebral hypoperfusion in Alzheimer disease and mild cognitive impairment measured with arterial spin-labeling MR imaging: initial experience. Radiology 2005; 234: 851-9.
70. Callen DJ, Black SE, Caldwell CB. Limbic system perfusion in Alzheimer's disease measured by MRI-coregistered HMPAO SPECT. Eur J Nucl Med Mol Imaging 2002; 29: 899-906.
71. Hanada K, Hosono M, Kudo T, Hitomi Y, Yagyu Y, Kirime E, et al. Regional cerebral blood flow in the assessment of major depression and Alzheimer's disease in the early elderly. Nucl Med Commun 2006; 27: 535-41.
72. Nobili F, Koulibaly M, Vitali P, Migneco O, Mariani G, Ebmeier K, et al. Brain perfusion follow-up in Alzheimer's patients during treatment with acetylcholinesterase inhibitors. J Nucl Med 2002; 43: 983-90.
73. Hanyu H, Shimizu S, Hirao K, Kanetaka H, Sakurai H, Iwamoto T, et al. Differentiation of dementia with Lewy bodies from Alzheimer's disease using Mini-Mental State Examination and brain perfusion SPECT. J Neurol Sci 2006; 250: 97-102.
74. Kasama S, Tachibana H, Kawabata K, Yoshikawa H. Cerebral blood flow in Parkinson's disease, dementia with Lewy bodies, and Alzheimer's disease according to three-dimensional stereotactic surface projection imaging. Dement Geriatr Cogn Disord 2005; 19: 266-75.
75. Defebvre LJ, Leduc V, Duhamel A, Lecouffe P, Pasquier F, Lamy-Lhullier C, et al. Technetium HMPAO SPECT study in dementia with Lewy bodies, Alzheimer's disease and idiopathic Parkinson's disease. J Nucl Med 1999; 40: 956-62.
76. Charpentier P, Lavenu I, Defebvre L, Duhamel A, Lecouffe P, Pasquier F, et al. Alzheimer's disease and frontotemporal dementia are differentiated by discriminant analysis applied to (99m)Tc HmPAO SPECT data. J Neurol Neurosurg Psychiatry 2000; 69: 661-3.