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Volumn 10, Issue 2, 2010, Pages 123-128

From tumor size and HER2 status to systems oncology for very early breast cancer treatment

Author keywords

[No Author keywords available]

Indexed keywords

BRCA2 PROTEIN; DNA; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR; TRASTUZUMAB;

EID: 76749112093     PISSN: 14737140     EISSN: 17448328     Source Type: Journal    
DOI: 10.1586/ERA.09.177     Document Type: Editorial
Times cited : (86)

References (44)
  • 1
    • 69449090120 scopus 로고    scopus 로고
    • Panel members. Thresholds for therapies: Highlights of the St Gallen International Expert Consensus on the primary therapy of early breast cancer 2009
    • Goldhirsch A, Ingle JN, Gelber RD, Coates AS, Thürlimann B, Senn HJ; Panel members. Thresholds for therapies: highlights of the St Gallen International Expert Consensus on the primary therapy of early breast cancer 2009. Ann. Oncol. 20(8), 1319-1329 (2009).
    • (2009) Ann. Oncol , vol.20 , Issue.8 , pp. 1319-1329
    • Goldhirsch, A.1    Ingle, J.N.2    Gelber, R.D.3    Coates, A.S.4    Thürlimann, B.5    Senn, H.J.6
  • 2
    • 76749089104 scopus 로고    scopus 로고
    • National Comprehensive Cancer Network, National Comprehensive Cancer Network, PA, USA
    • National Comprehensive Cancer Network. Guidelines for Treatment of Cancer by Site. National Comprehensive Cancer Network, PA, USA (2009).
    • (2009) Guidelines for Treatment of Cancer by Site
  • 3
    • 26844457534 scopus 로고    scopus 로고
    • The distinctive nature of HER2-positive breast cancers
    • Burstein HJ. The distinctive nature of HER2-positive breast cancers. N. Engl. J. Med. 353(16), 1652-1654 (2005).
    • (2005) N. Engl. J. Med , vol.353 , Issue.16 , pp. 1652-1654
    • Burstein, H.J.1
  • 4
    • 26844559765 scopus 로고    scopus 로고
    • Trastuzumab in the treatment of breast cancer
    • Hortobagyi GN. Trastuzumab in the treatment of breast cancer. N. Engl. J. Med. 353(16), 1734-1736 (2005).
    • (2005) N. Engl. J. Med , vol.353 , Issue.16 , pp. 1734-1736
    • Hortobagyi, G.N.1
  • 6
    • 53649106195 scopus 로고    scopus 로고
    • Next-generation DNA sequencing
    • Shendure J, Ji H. Next-generation DNA sequencing. Nat. Biotechnol. 26, 1135-1145 (2008).
    • (2008) Nat. Biotechnol , vol.26 , pp. 1135-1145
    • Shendure, J.1    Ji, H.2
  • 7
    • 33846326304 scopus 로고    scopus 로고
    • Genetic screening for signal transduction in the era of network biology
    • Friedman A, Perrimon N. Genetic screening for signal transduction in the era of network biology. Cell 128, 225-231 (2007).
    • (2007) Cell , vol.128 , pp. 225-231
    • Friedman, A.1    Perrimon, N.2
  • 8
    • 62549110855 scopus 로고    scopus 로고
    • Personalizing medicine: A systems biology perspective
    • Deisboeck TS. Personalizing medicine: a systems biology perspective. Mol. Syst. Biol. 5, 249 (2009).
    • (2009) Mol. Syst. Biol , vol.5 , pp. 249
    • Deisboeck, T.S.1
  • 9
    • 74749106342 scopus 로고    scopus 로고
    • Novel clinico-genome network modelling for revolutionizing genotypephenotype-based personalized cancer care
    • 2010
    • Roukos DH. Novel clinico-genome network modelling for revolutionizing genotypephenotype-based personalized cancer care. Exp. Rev. Mol. Diagn. 10(1), 33-48 (2010).
    • Exp. Rev. Mol. Diagn , vol.10 , Issue.1 , pp. 33-48
    • Roukos, D.H.1
  • 10
    • 73349119689 scopus 로고    scopus 로고
    • High risk of recurrence for patients with breast cancer who have human epidermal growth factor receptor 2-positive, node-negative tumors 1 cm or smaller
    • Gonzalez-Angulo AM, Litton JK, Broglio KR et al. High risk of recurrence for patients with breast cancer who have human epidermal growth factor receptor 2-positive, node-negative tumors 1 cm or smaller. J. Clin. Oncol. 27(34), 5700-5706 (2009).
    • (2009) J. Clin. Oncol , vol.27 , Issue.34 , pp. 5700-5706
    • Gonzalez-Angulo, A.M.1    Litton, J.K.2    Broglio, K.R.3
  • 11
    • 73349142700 scopus 로고    scopus 로고
    • Clinical relevance of HER2 overexpression/ amplification in patients with small tumor size and node-negative breast cancer
    • Curigliano G, Viale G, Bagnardi V. Clinical relevance of HER2 overexpression/ amplification in patients with small tumor size and node-negative breast cancer. J. Clin. Oncol. 27(34), 5693-5699 (2009).
    • (2009) J. Clin. Oncol , vol.27 , Issue.34 , pp. 5693-5699
    • Curigliano, G.1    Viale, G.2    Bagnardi, V.3
  • 12
    • 0037341394 scopus 로고    scopus 로고
    • Amplification of erbB2 and erbB2 expression are superior to estrogen receptor status as risk factors for distant recurrence in pT1N0M0 breast cancer: A nationwide population-based study
    • Joensuu H, Isola J, Lundin M et al. Amplification of erbB2 and erbB2 expression are superior to estrogen receptor status as risk factors for distant recurrence in pT1N0M0 breast cancer: a nationwide population-based study. Clin. Cancer Res. 9(3), 923-930 (2003).
    • (2003) Clin. Cancer Res , vol.9 , Issue.3 , pp. 923-930
    • Joensuu, H.1    Isola, J.2    Lundin, M.3
  • 13
    • 34248362598 scopus 로고    scopus 로고
    • Recurrence risk in T1a-b, node-negative, HER2 positive breast cancer, 100(Suppl. 1, S92 , Abstract 2037
    • Black D, Younger J, Martei Y et al. Recurrence risk in T1a-b, node-negative, HER2 positive breast cancer. Breast Cancer Res. Treat. 100(Suppl. 1), S92 (2006) (Abstract 2037).
    • (2006) Breast Cancer Res. Treat
    • Black, D.1    Younger, J.2    Martei, Y.3
  • 14
    • 76749155163 scopus 로고    scopus 로고
    • Rakkhit R, Broglio K, Peintinger F et al. Significant increased recurrence rates among breast cancer patients with HER2 positive, T1a-b,N0M0 tumors. Cancer Therapy and Reseach Center at University of Texas - American Association for Cancer Research Breast Cancer Symposium, San Antonio, TX, December 10-14, (2008). Cancer Res. 69(Suppl.), S96 (2009) (Abstract 701).
    • Rakkhit R, Broglio K, Peintinger F et al. Significant increased recurrence rates among breast cancer patients with HER2 positive, T1a-b,N0M0 tumors. Cancer Therapy and Reseach Center at University of Texas - American Association for Cancer Research Breast Cancer Symposium, San Antonio, TX, December 10-14, (2008). Cancer Res. 69(Suppl.), S96 (2009) (Abstract 701).
  • 15
    • 33344478381 scopus 로고    scopus 로고
    • Adjuvant docetaxel or vinorelbine with or without trastuzumab for breast cancer
    • Joensuu H, Kellokumpu-Lehtinen P-L, Bono P et al. Adjuvant docetaxel or vinorelbine with or without trastuzumab for breast cancer. N. Engl. J. Med. 354(8), 809-820 (2006).
    • (2006) N. Engl. J. Med , vol.354 , Issue.8 , pp. 809-820
    • Joensuu, H.1    Kellokumpu-Lehtinen, P.-L.2    Bono, P.3
  • 16
    • 26844503270 scopus 로고    scopus 로고
    • Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer
    • Piccart-Gebhart MJ, Procter M, Leyland-Jones B et al. Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. N. Engl. J. Med. 353(16), 1659-1672 (2005).
    • (2005) N. Engl. J. Med , vol.353 , Issue.16 , pp. 1659-1672
    • Piccart-Gebhart, M.J.1    Procter, M.2    Leyland-Jones, B.3
  • 17
    • 26844536978 scopus 로고    scopus 로고
    • Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
    • Romond EH, Perez EA, Bryant J et al. Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer. N. Engl. J. Med. 353(16), 1673-1684 (2005).
    • (2005) N. Engl. J. Med , vol.353 , Issue.16 , pp. 1673-1684
    • Romond, E.H.1    Perez, E.A.2    Bryant, J.3
  • 18
    • 34248658992 scopus 로고    scopus 로고
    • BCIRG 006: 2nd interim analysis Phase III randomized trial comparing doxorubicin and cyclophosphamide followed by docetaxel with doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab with docetaxel, carboplatin and trastuzumab in HER2/neu positive early breast cancer patients
    • Presented at:, San Antonio, TX, USA, 14-17 December
    • Slamon D, Eiermann W, Robert N et al. BCIRG 006: 2nd interim analysis Phase III randomized trial comparing doxorubicin and cyclophosphamide followed by docetaxel with doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab with docetaxel, carboplatin and trastuzumab in HER2/neu positive early breast cancer patients. Presented at: 29th Annual San Antonio Breast Cancer Symposium. San Antonio, TX, USA, 14-17 December 2006.
    • (2006) 29th Annual San Antonio Breast Cancer Symposium
    • Slamon, D.1    Eiermann, W.2    Robert, N.3
  • 19
    • 36849075170 scopus 로고    scopus 로고
    • Increasing use of contralateral prophylactic mastectomy for breast cancer patients: A trend toward more aggressive surgical treatment
    • Tuttle TM, Habermann EB, Grund EH, Morris TJ, Virnig BA. Increasing use of contralateral prophylactic mastectomy for breast cancer patients: a trend toward more aggressive surgical treatment. J. Clin. Oncol. 25(33), 5203-5209 (2007).
    • (2007) J. Clin. Oncol , vol.25 , Issue.33 , pp. 5203-5209
    • Tuttle, T.M.1    Habermann, E.B.2    Grund, E.H.3    Morris, T.J.4    Virnig, B.A.5
  • 20
    • 63249084150 scopus 로고    scopus 로고
    • Radiation therapy for breast cancer
    • Roukos DH. Radiation therapy for breast cancer. N. Engl. J. Med. 360(13), 1362 (2009).
    • (2009) N. Engl. J. Med , vol.360 , Issue.13 , pp. 1362
    • Roukos, D.H.1
  • 21
    • 74649083025 scopus 로고    scopus 로고
    • Targeting gastric cancer with trastuzumab: New clinical practice and innovative developments to overcome resistance
    • 2010
    • Roukos DH. Targeting gastric cancer with trastuzumab: new clinical practice and innovative developments to overcome resistance. Ann. Surg. Oncol. 17, 14-17 (2010).
    • Ann. Surg. Oncol , vol.17 , pp. 14-17
    • Roukos, D.H.1
  • 22
    • 34548444589 scopus 로고    scopus 로고
    • Adjuvant trastuzumab in the treatment of HER-2-positive early breast cancer: A meta-analysis of published randomized trials
    • Viani G, Afonso S, Stefano E et al. Adjuvant trastuzumab in the treatment of HER-2-positive early breast cancer: a meta-analysis of published randomized trials. BMC Cancer 7, 153 (2007).
    • (2007) BMC Cancer , vol.7 , pp. 153
    • Viani, G.1    Afonso, S.2    Stefano, E.3
  • 23
    • 68849115626 scopus 로고    scopus 로고
    • Micrometastases or isolated tumor cells and the outcome of breast cancer
    • de Boer M, van Deurzen CH, van Dijck JA et al. Micrometastases or isolated tumor cells and the outcome of breast cancer. N. Engl. J. Med. 361(7), 653-663 (2009).
    • (2009) N. Engl. J. Med , vol.361 , Issue.7 , pp. 653-663
    • de Boer, M.1    van Deurzen, C.H.2    van Dijck, J.A.3
  • 24
    • 70449641339 scopus 로고    scopus 로고
    • Isolated tumor cells in breast cancer
    • Roukos DH. Isolated tumor cells in breast cancer. N. Engl. J. Med. 361, 1994-1995 (2009).
    • (2009) N. Engl. J. Med , vol.361 , pp. 1994-1995
    • Roukos, D.H.1
  • 25
    • 60849097255 scopus 로고    scopus 로고
    • Gene-expression signatures in breast cancer
    • Sotiriou C, Pusztai L. Gene-expression signatures in breast cancer. N. Engl. J. Med. 360(8), 790-800 (2009).
    • (2009) N. Engl. J. Med , vol.360 , Issue.8 , pp. 790-800
    • Sotiriou, C.1    Pusztai, L.2
  • 26
    • 62449163752 scopus 로고    scopus 로고
    • Twenty-one-gene assay: Challenges and promises in translating personal genomics and whole-genome scans into personalized treatment of breast cancer
    • Roukos DH. Twenty-one-gene assay: challenges and promises in translating personal genomics and whole-genome scans into personalized treatment of breast cancer. J. Clin. Oncol. 27(8), 1337-1338 (2009).
    • (2009) J. Clin. Oncol , vol.27 , Issue.8 , pp. 1337-1338
    • Roukos, D.H.1
  • 27
    • 0035900920 scopus 로고    scopus 로고
    • Prognosis and treatment of patients with breast tumors of one centimeter or less and negative axillary lymph nodes
    • Fisher B, Dignam J, Tan-Chiu E et al. Prognosis and treatment of patients with breast tumors of one centimeter or less and negative axillary lymph nodes. J. Natl Cancer Inst. 93, 112-120 (2001).
    • (2001) J. Natl Cancer Inst , vol.93 , pp. 112-120
    • Fisher, B.1    Dignam, J.2    Tan-Chiu, E.3
  • 28
    • 19344364880 scopus 로고    scopus 로고
    • Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomized trials
    • Early Breast Cancer Trialists' Collaborative Group EBCTCG
    • Early Breast Cancer Trialists' Collaborative Group (EBCTCG). Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomized trials. Lancet 365, 1687-1717 (2005).
    • (2005) Lancet , vol.365 , pp. 1687-1717
  • 29
    • 0019183253 scopus 로고
    • On the nature of susceptibility to cancer. The presidential address
    • Miller DG. On the nature of susceptibility to cancer. The presidential address. Cancer 46, 1307-1318 (1980).
    • (1980) Cancer , vol.46 , pp. 1307-1318
    • Miller, D.G.1
  • 30
    • 38449094794 scopus 로고    scopus 로고
    • Oncogenic transformation and experimental models of human cancer
    • Schinzel AC, Hahn WC. Oncogenic transformation and experimental models of human cancer. Front. Biosci. 13, 71-84 (2008).
    • (2008) Front. Biosci , vol.13 , pp. 71-84
    • Schinzel, A.C.1    Hahn, W.C.2
  • 31
    • 36248962105 scopus 로고    scopus 로고
    • The genomic landscapes of human breast and colorectal cancers
    • Wood LD, Parsons DW, Jones S. The genomic landscapes of human breast and colorectal cancers. Science 318(5853), 1108-1113 (2007).
    • (2007) Science , vol.318 , Issue.5853 , pp. 1108-1113
    • Wood, L.D.1    Parsons, D.W.2    Jones, S.3
  • 32
    • 52149123619 scopus 로고    scopus 로고
    • Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
    • Jones S, Zhang X, Parsons DW. Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science 321(5897), 1801-1806 (2008).
    • (2008) Science , vol.321 , Issue.5897 , pp. 1801-1806
    • Jones, S.1    Zhang, X.2    Parsons, D.W.3
  • 33
    • 66249090533 scopus 로고    scopus 로고
    • Systems biology: When it is time to die
    • Bastiaens P. Systems biology: when it is time to die. Nature 459(7245), 334-335 (2009).
    • (2009) Nature , vol.459 , Issue.7245 , pp. 334-335
    • Bastiaens, P.1
  • 34
    • 33745728170 scopus 로고    scopus 로고
    • Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells
    • Liu S, Dontu G, Mantle ID et al. Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells. Cancer Res. 66, 6063-6071 (2006).
    • (2006) Cancer Res , vol.66 , pp. 6063-6071
    • Liu, S.1    Dontu, G.2    Mantle, I.D.3
  • 35
    • 41549152176 scopus 로고    scopus 로고
    • Wnt signaling pathway in invasive ductal carcinoma of the breast: Relationship between b-catenin, disheveled and cyclin D1 expression
    • Prasad CP, Gupta SD, Rath G et al. Wnt signaling pathway in invasive ductal carcinoma of the breast: relationship between b-catenin, disheveled and cyclin D1 expression. Oncology 73, 112-117 (2007).
    • (2007) Oncology , vol.73 , pp. 112-117
    • Prasad, C.P.1    Gupta, S.D.2    Rath, G.3
  • 36
    • 36248953716 scopus 로고    scopus 로고
    • Mammary stem cells and breast cancer - role of notch signaling
    • Farnie G, Clarke R. Mammary stem cells and breast cancer - role of notch signaling. Stem Cell Rev. 3, 169-175 (2007).
    • (2007) Stem Cell Rev , vol.3 , pp. 169-175
    • Farnie, G.1    Clarke, R.2
  • 38
    • 9244241576 scopus 로고    scopus 로고
    • Identification of human brain tumour initiating cells
    • Singh SK, Hawkins C, Clarke ID et al. Identification of human brain tumour initiating cells. Nature 432, 396-401 (2004).
    • (2004) Nature , vol.432 , pp. 396-401
    • Singh, S.K.1    Hawkins, C.2    Clarke, I.D.3
  • 39
    • 33846100356 scopus 로고    scopus 로고
    • A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
    • O'Brien CA, Pollett A, Gallinger S, Dick JE. A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 445, 106-110 (2007).
    • (2007) Nature , vol.445 , pp. 106-110
    • O'Brien, C.A.1    Pollett, A.2    Gallinger, S.3    Dick, J.E.4
  • 40
    • 33846095137 scopus 로고    scopus 로고
    • Identification and expansion of human colon-cancer-initiating cells
    • Ricci-Vitiani L, Lombardi DG, Pilozzi E et al. Identification and expansion of human colon-cancer-initiating cells. Nature 445, 111-115 (2007).
    • (2007) Nature , vol.445 , pp. 111-115
    • Ricci-Vitiani, L.1    Lombardi, D.G.2    Pilozzi, E.3
  • 41
    • 38349165576 scopus 로고    scopus 로고
    • Identification of cells initiating human melanomas
    • Schatton T, Murphy GF, Frank NY et al. Identification of cells initiating human melanomas. Nature 451, 345-349 (2008).
    • (2008) Nature , vol.451 , pp. 345-349
    • Schatton, T.1    Murphy, G.F.2    Frank, N.Y.3
  • 42
    • 77149145162 scopus 로고    scopus 로고
    • Characterizing the HER2/neu status and metastatic potential of breast cancer stem/progenitor cells
    • DOI: 10.1245/s10434-009-0730-z , Epub ahead of print
    • Pommier SJ, Quan GG, Christante D et al. Characterizing the HER2/neu status and metastatic potential of breast cancer stem/progenitor cells. Ann. Surg. Oncol. DOI: 10.1245/s10434-009-0730-z (2009) (Epub ahead of print).
    • (2009) Ann. Surg. Oncol
    • Pommier, S.J.1    Quan, G.G.2    Christante, D.3
  • 43
    • 65349131893 scopus 로고    scopus 로고
    • Cancer stem cells: A guide for skeptics
    • Tomasson MH. Cancer stem cells: a guide for skeptics. J. Cell. Biochem. 106(5), 745-749 (2009).
    • (2009) J. Cell. Biochem , vol.106 , Issue.5 , pp. 745-749
    • Tomasson, M.H.1
  • 44
    • 57349126306 scopus 로고    scopus 로고
    • Cancer stem cells: Here, there, everywhere?
    • Eaves CJ. Cancer stem cells: here, there, everywhere? Nature 456(7222), 581-582 (2008).
    • (2008) Nature , vol.456 , Issue.7222 , pp. 581-582
    • Eaves, C.J.1


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