A multicenter randomized controlled trial to assess the feasibility of testing modified ultrafiltration as a blood conservation technology in cardiac surgery

Journal of Thoracic and Cardiovascular Surgery

Volumn 139, Issue 3, 2010, Pages 701-706

  Boodhwani, Munir ^a   Hamilton, Andrew ^b   de Varennes, Benoit ^c   Mesana, Thierry ^a   Williams, K ^d   Wells, George A ^d   Nathan, H ^a   Dupuis, Jean Yves ^a   Babaev, A ^a   Wells, P ^d   Rubens, Fraser D ^a  

^a UNIVERSITY OF OTTAWA HEART INSTITUTE   (Canada)

^b QUEEN S UNIVERSITY   (Canada)

^c ROYAL VICTORIA HOSPITAL   (Canada)

^d UNIVERSITY OF OTTAWA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN; HYPERTENSIVE FACTOR; TRANEXAMIC ACID;

ADULT; AGED; ARTICLE; BLOOD CONSERVATION; BODY WEIGHT; CARDIOPULMONARY BYPASS; CLINICAL ASSESSMENT; CLINICAL PROTOCOL; CLINICAL TRIAL; CONFIDENCE INTERVAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ERYTHROCYTE TRANSFUSION; FEMALE; HEART SURGERY; HEMOCONCENTRATION; HUMAN; MALE; MULTICENTER STUDY; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; SHAM PROCEDURE; ULTRAFILTRATION;

AGED; BLOOD LOSS, SURGICAL; CARDIOPULMONARY BYPASS; DOUBLE-BLIND METHOD; FEASIBILITY STUDIES; FEMALE; HUMANS; MALE; PROSPECTIVE STUDIES; ULTRAFILTRATION;

EID: 76749109323     PISSN: 00225223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jtcvs.2009.11.056     Document Type: Article

References (10)

1. Ootaki Y., Yamaguchi M., Oshima Y., Yoshimura N., and Oka S. Effects of modified ultrafiltration on coagulation factors in pediatric cardiac surgery. Surg Today 32 (2002) 203-206
2. Friesen R.H., Campbell D.N., Clarke D.R., and Tornabene M.A. Modified ultrafiltration attenuates dilutional coagulopathy in pediatric open heart operations. Ann Thorac Surg 64 (1997) 1787-1789
3. Leyh R.G., Bartels C., Joubert-Hubner E., Bechtel J.F., and Sievers H.H. Influence of modified ultrafiltration on coagulation, fibrinolysis and blood loss in adult cardiac surgery. Eur J Cardiothorac Surg 19 (2001) 145-151
4. Chew M.S., Brix-Christensen V., Ravn H.B., Brandslund I., Ditlevsen E., Pedersen J., et al. Effect of modified ultrafiltration on the inflammatory response in paediatric open-heart surgery: a prospective, randomized study. Perfusion 17 (2002) 327-333
5. Tassani P., Richter J.A., Eising G.P., Barankay A., Braun S.L., Haehnel C.H., et al. Influence of combined zero-balanced and modified ultrafiltration on the systemic inflammatory response during coronary artery bypass grafting. J Cardiothorac Vasc Anesth 13 (1999) 285-291
6. Boodhwani M., Williams K., Babaev A., Gill G., Saleem N., and Rubens F.D. Ultrafiltration reduces blood transfusions following cardiac surgery: a meta-analysis. Eur J Cardiothorac Surg 30 (2006) 892-897
7. Luciani G.B., Menon T., Vecchi B., Auriemma S., and Mazzucco A. Modified ultrafiltration reduces morbidity after adult cardiac operations: a prospective, randomized clinical trial. Circulation 104 12 Suppl. 1 (2001) I253-I259
8. Boldt J., Zickmann B., Fedderson B., Herold C., Dapper F., and Hempelmann G. Six different hemofiltration devices for blood conservation in cardiac surgery. Ann Thorac Surg 51 (1991) 747-753
9. Bang H., Ni L., and Davis C.E. Assessment of blinding in clinical trials. Control Clin Trials 25 (2004) 143-156
10. Shevde K., Pagala M., Kashikar A., Tyagaraj C., Shahbaz N., Iqbal M., et al. Gender is an essential determinant of blood transfusion in patients undergoing coronary artery bypass graft procedure. J Clin Anesth 12 (2000) 109-116