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Volumn 30, Issue 12, 2009, Pages 2879-2880

Antihyperglycemic effects of methylenedisalicylic acid

Author keywords

Antihyperglycemic; IKK ; Methylenedisalicylic acid; Mouse; PTP1B

Indexed keywords


EID: 76749093185     PISSN: 02532964     EISSN: 12295949     Source Type: Journal    
DOI: 10.5012/bkcs.2009.30.12.2879     Document Type: Article
Times cited : (3)

References (14)
  • 12
    • 76749151901 scopus 로고    scopus 로고
    • Note
    • 2O (50 mL containing 2.0 equivalents of NaOH solution), mixed in powdered food (500 g), and kneaded to form a dough. Body weight and food intake were recorded every 3 d through- out the study. For the glucose tolerance test, mice were fasted for 6 h and glucose (1.0 g/kg of body weight) injected intraperitoneally. Blood glucose levels were measured from tail bleeds with a glu- cometer (Accu check active, Roche diagnostics, Ireland) at 0 (prior to glucose administration), 20, 40, 60, 90, and 120 min after glucose injection. After a 5 d recovery period on their own diet (the test group on HFD plus MDSA), mice were fasted overnight and blood collected by cardiac puncture under secobarbital anesthesia. Liver, lung, kidney, and white adipose tissue were excised and weighed. Plasma was analyzed for glucose, triglyceride, total cholesterol and free fatty acids using diagnostic kits (Glucose C2, TG E, T-Cho E and NEFA C from Wako Pure Chemical Industries, Ltd. Osaka, Japan).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.