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Volumn 35, Issue 4, 2010, Pages 851-852

Allosteric antipsychotics: M4 muscarinic potentiators as novel treatments for schizophrenia

Author keywords

[No Author keywords available]

Indexed keywords

ATYPICAL ANTIPSYCHOTIC AGENT; G PROTEIN COUPLED RECEPTOR; LY 2033298; MUSCARINIC AGENT; MUSCARINIC M4 RECEPTOR; NEUROLEPTIC AGENT; NORCLOZAPINE; OXOTREMORINE; UNCLASSIFIED DRUG; XANOMELINE;

EID: 76749091482     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/npp.2009.206     Document Type: Note
Times cited : (19)

References (11)
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  • 3
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    • Christopoulos, A.1
  • 4
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    • The highly efficacious actions of N-desmethylclozapine at muscarinic receptors are unique and not a common property of either typical or atypical antipsychotic drugs: Is M1 agonism a pre-requisite for mimicking clozapine's actions?
    • Davies MA, Compton-Toth BA, Hufeisen SJ, Meltzer HY, Roth BL (2005). The highly efficacious actions of N-desmethylclozapine at muscarinic receptors are unique and not a common property of either typical or atypical antipsychotic drugs: is M1 agonism a pre-requisite for mimicking clozapine's actions? Psycho-pharmacology (Berl) 178: 451-460.
    • (2005) Psycho-pharmacology (Berl) , vol.178 , pp. 451-460
    • Davies, M.A.1    Compton-Toth, B.A.2    Hufeisen, S.J.3    Meltzer, H.Y.4    Roth, B.L.5
  • 5
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    • Hyperactivity, elevated dopaminergic transmission, and response to amphetamine in M1 muscarinic acetylcholine receptor-deficient mice
    • Gerber DJ, Sotnikova TD, Gainetdinov RR, Huang SY, Caron MG, Tonegawa S (2001). Hyperactivity, elevated dopaminergic transmission, and response to amphetamine in M1 muscarinic acetylcholine receptor-deficient mice. Proc Natl Acad Sci USA 98: 15312-15317.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 15312-15317
    • Gerber, D.J.1    Sotnikova, T.D.2    Gainetdinov, R.R.3    Huang, S.Y.4    Caron, M.G.5    Tonegawa, S.6
  • 6
    • 13044283415 scopus 로고    scopus 로고
    • Enhancement of D1 dopamine receptor-mediated locomotor stimulation in M(4) muscarinic acetylcholine receptor knockout mice
    • Gomeza J, Zhang L, Kostenis E, Felder C, Bymaster F, Brodkin J et al (1999). Enhancement of D1 dopamine receptor-mediated locomotor stimulation in M(4) muscarinic acetylcholine receptor knockout mice. Proc Natl Acad Sci USA 96: 10483-10488.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 10483-10488
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  • 7
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    • Leach K, Loiacono RE, Felder CC, McKinzie DL, Mogg A, Shaw DB et al (2010). Molecular mechanisms of action and in vivo validation of an M4 muscarinic acetylcholine receptor allosteric modulator with potential antipsychotic properties. Neuro-psychopharmacology 35: 855-869.
    • Neuro-psychopharmacology , vol.35 , pp. 855-869
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  • 8
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  • 10
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.