-
1
-
-
0030902127
-
Effects of xanomeline, a selective muscarinic receptor agonist, on cognitive function and behavioral symptoms in Alzheimer's disease
-
Bodick NC, Offen WW, Levey AI, Cutler NR, Gauthier SG, Satlin A et al (1997). Effects of xanomeline, a selective muscarinic receptor agonist, on cognitive function and behavioral symptoms in Alzheimer's disease. Arch Neurol 54: 465-473.
-
(1997)
Arch Neurol
, vol.54
, pp. 465-473
-
-
Bodick, N.C.1
Offen, W.W.2
Levey, A.I.3
Cutler, N.R.4
Gauthier, S.G.5
Satlin, A.6
-
2
-
-
49449108109
-
Allosteric modulation of the muscarinic M4 receptor as an approach to treating schizophrenia
-
Chan WY, McKinzie DL, Bose S, Mitchell SN, Witkin JM, Thompson RC et al (2008). Allosteric modulation of the muscarinic M4 receptor as an approach to treating schizophrenia. Proc Natl Acad Sci USA 105: 10978-10983.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 10978-10983
-
-
Chan, W.Y.1
McKinzie, D.L.2
Bose, S.3
Mitchell, S.N.4
Witkin, J.M.5
Thompson, R.C.6
-
3
-
-
0036490942
-
Allosteric binding sites on cell-surface receptors: Novel targets for drug discovery
-
Christopoulos A (2002). Allosteric binding sites on cell-surface receptors: novel targets for drug discovery. Nat Rev Drug Discov 1: 198-210.
-
(2002)
Nat Rev Drug Discov
, vol.1
, pp. 198-210
-
-
Christopoulos, A.1
-
4
-
-
16844363204
-
The highly efficacious actions of N-desmethylclozapine at muscarinic receptors are unique and not a common property of either typical or atypical antipsychotic drugs: Is M1 agonism a pre-requisite for mimicking clozapine's actions?
-
Davies MA, Compton-Toth BA, Hufeisen SJ, Meltzer HY, Roth BL (2005). The highly efficacious actions of N-desmethylclozapine at muscarinic receptors are unique and not a common property of either typical or atypical antipsychotic drugs: is M1 agonism a pre-requisite for mimicking clozapine's actions? Psycho-pharmacology (Berl) 178: 451-460.
-
(2005)
Psycho-pharmacology (Berl)
, vol.178
, pp. 451-460
-
-
Davies, M.A.1
Compton-Toth, B.A.2
Hufeisen, S.J.3
Meltzer, H.Y.4
Roth, B.L.5
-
5
-
-
0035910050
-
Hyperactivity, elevated dopaminergic transmission, and response to amphetamine in M1 muscarinic acetylcholine receptor-deficient mice
-
Gerber DJ, Sotnikova TD, Gainetdinov RR, Huang SY, Caron MG, Tonegawa S (2001). Hyperactivity, elevated dopaminergic transmission, and response to amphetamine in M1 muscarinic acetylcholine receptor-deficient mice. Proc Natl Acad Sci USA 98: 15312-15317.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 15312-15317
-
-
Gerber, D.J.1
Sotnikova, T.D.2
Gainetdinov, R.R.3
Huang, S.Y.4
Caron, M.G.5
Tonegawa, S.6
-
6
-
-
13044283415
-
Enhancement of D1 dopamine receptor-mediated locomotor stimulation in M(4) muscarinic acetylcholine receptor knockout mice
-
Gomeza J, Zhang L, Kostenis E, Felder C, Bymaster F, Brodkin J et al (1999). Enhancement of D1 dopamine receptor-mediated locomotor stimulation in M(4) muscarinic acetylcholine receptor knockout mice. Proc Natl Acad Sci USA 96: 10483-10488.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 10483-10488
-
-
Gomeza, J.1
Zhang, L.2
Kostenis, E.3
Felder, C.4
Bymaster, F.5
Brodkin, J.6
-
7
-
-
76749144987
-
Molecular mechanisms of action and in vivo validation of an M4 muscarinic acetylcholine receptor allosteric modulator with potential antipsychotic properties
-
Leach K, Loiacono RE, Felder CC, McKinzie DL, Mogg A, Shaw DB et al (2010). Molecular mechanisms of action and in vivo validation of an M4 muscarinic acetylcholine receptor allosteric modulator with potential antipsychotic properties. Neuro-psychopharmacology 35: 855-869.
-
Neuro-psychopharmacology
, vol.35
, pp. 855-869
-
-
Leach, K.1
Loiacono, R.E.2
Felder, C.C.3
McKinzie, D.L.4
Mogg, A.5
Shaw, D.B.6
-
8
-
-
4644271084
-
Magic shotguns versus magic bullets: Selectively non-selective drugs for mood disorders and schizophrenia
-
Roth BL, Sheffler DJ, Kroeze WK (2004). Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia. Nat Rev Drug Discov 3: 353-359.
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 353-359
-
-
Roth, B.L.1
Sheffler, D.J.2
Kroeze, W.K.3
-
9
-
-
78651013959
-
The effects of diiso-propylfluorophosphate in schizophrenia and manic-depressive psychosis
-
Rowntree DW, Nevin S, Wilson A (1950). The effects of diiso-propylfluorophosphate in schizophrenia and manic-depressive psychosis. J Neurol Neurosurg 13: 47-62.
-
(1950)
J Neurol Neurosurg
, vol.13
, pp. 47-62
-
-
Rowntree, D.W.1
Nevin, S.2
Wilson, A.3
-
10
-
-
0034607566
-
Xanomeline an M(1)/ M(4) preferring muscarinic cholinergic receptor agonist, produces antipsychotic-like activity in rats and mice
-
Shannon HE, Rasmussen K, Bymaster FP, Hart JC, Peters SC, Swedberg MD et al (2000). Xanomeline, an M(1)/M(4) preferring muscarinic cholinergic receptor agonist, produces antipsychotic-like activity in rats and mice. Schizophr Res 42: 249-259.
-
(2000)
Schizophr Res
, vol.42
, pp. 249-259
-
-
Shannon, H.E.1
Rasmussen, K.2
Bymaster, F.P.3
Hart, J.C.4
Peters, S.C.5
Swedberg, M.D.6
-
11
-
-
0016138354
-
Antischizophrenic drugs and brain cholinergic receptors affinity for muscarinic sites predicts extrapyramidal effects
-
Snyder S, Greenberg D, Yamamura HI (1974). Antischizophrenic drugs and brain cholinergic receptors affinity for muscarinic sites predicts extrapyramidal effects. Arch Gen Psychiatry 31: 58-61.
-
(1974)
Arch Gen Psychiatry
, vol.31
, pp. 58-61
-
-
Snyder, S.1
Greenberg, D.2
Yamamura, H.I.3
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