Homologous recombination in the antibiotic producer Penicillium chrysogenum: Strain Δpcku70 shows up-regulation of genes from the HOG pathway

Applied Microbiology and Biotechnology

Volumn 85, Issue 4, 2010, Pages 1081-1094

  Hoff, Birgit ^a   Kamerewerd, Jens ^a   Sigl, Claudia ^b   Zadra, Ivo ^b   Kück, Ulrich ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Lactam biosynthesis; Array analysis; Gene targeting; HOG signalling pathway; Non homologous end joining; PcbC; Pcku70; Pcrfx1; Penicillium chrysogenum; Velvet

Indexed keywords

ARRAY ANALYSIS; GENE TARGETING; NONHOMOLOGOUS END JOINING; PCBC; PENICILLIUM CHRYSOGENUM; SIGNALLING PATHWAYS;

ANTIBIOTICS; BIOCHEMISTRY; BIOSYNTHESIS; GENETIC ENGINEERING; JOINING; PLANTS (BOTANY); SILK;

GENE ENCODING;

BETA LACTAM ANTIBIOTIC; DNA BINDING PROTEIN;

ANTIBIOTICS; BIOCHEMISTRY; BIOTECHNOLOGY; FUNGUS; GENE EXPRESSION; OSMOSIS; PROTEIN;

ANTIBIOTIC BIOSYNTHESIS; ARTICLE; BACTERIAL GENE; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; DELETION MUTANT; GENE CASSETTE; GENE DELETION; GENE DISRUPTION; GENE EXPRESSION REGULATION; GENE ISOLATION; GENE SEQUENCE; GENE TARGETING; GENETIC STRAIN; GENETIC TRANSDUCTION; HOMOLOGOUS RECOMBINATION; KNOCKOUT GENE; MICROARRAY ANALYSIS; NONHUMAN; OSMOTIC STRESS; PENICILLIUM CHRYSOGENUM; PENICILLIUM CHRYSOGENUM DELTA70; SENSITIVITY ANALYSIS; SEQUENCE ANALYSIS; UPREGULATION; VEGETATIVE GROWTH;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; BIOSYNTHETIC PATHWAYS; DNA, FUNGAL; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, FUNGAL; GENE KNOCKOUT TECHNIQUES; GENETIC MARKERS; GLYCEROL; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OSMOLAR CONCENTRATION; PENICILLINS; PENICILLIUM CHRYSOGENUM; SPECIES SPECIFICITY; UP-REGULATION;

EUKARYOTA; PENICILLIUM CHRYSOGENUM;

EID: 76649128069     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-009-2168-4     Document Type: Article

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