Genetic comparison of a croatian isolate and CEPH European founders

Genetic Epidemiology

Volumn 34, Issue 2, 2010, Pages 140-145

  Navarro, Pau ^a   Vitart, Véronique ^a   Hayward, Caroline ^a   Tenesa, Albert ^b   Zgaga, Lina ^c   Juricic, Danica ^d   Polasek, Ozren ^b,c   Hastie, Nicholas D ^a   Rudan, Igor ^b,e   Campbell, Harry ^b   Wright, Alan F ^a   Haley, Chris S ^a   Knott, Sara A ^b  

^a WESTERN GENERAL HOSPITAL   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c UNIVERSITY OF ZAGREB   (Croatia)

^d UNIVERSITY OF ZAGREB   (Croatia)

^e UNIVERSITY OF SPLIT   (Croatia)

Author keywords

Linkage disequilibrium; Mapping; Population isolate

Indexed keywords

ARTICLE; CROATIA; EUROPE; GENE FREQUENCY; GENE ISOLATION; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENE MAPPING; GENETIC ASSOCIATION; GENOTYPE; HOMOZYGOTE; HUMAN; HUMAN EXPERIMENT; QUANTITATIVE TRAIT LOCUS; SINGLE NUCLEOTIDE POLYMORPHISM;

CHROMOSOME MAPPING; CROATIA; EUROPEAN CONTINENTAL ANCESTRY GROUP; FOUNDER EFFECT; GENE FREQUENCY; GENETIC VARIATION; GENETICS, POPULATION; GENOTYPE; HUMANS; LINKAGE DISEQUILIBRIUM; MODELS, GENETIC; MODELS, STATISTICAL; QUANTITATIVE TRAIT LOCI; UTAH;

EID: 76649128055     PISSN: 07410395     EISSN: 10982272     Source Type: Journal    
DOI: 10.1002/gepi.20443     Document Type: Article

References (24)

1. Bakija-Konsuo A, Basta-Juzbasic A, Rudan I, Situm M, Nardelli-Kovacic M, Levanat S, Fischer J, Hohl D, Loncaric D, Seiwert S, Campbell H. 2002. Mal de Meleda: genetic haplotype analysis and clinicopathological findings in cases originating from the island of Mljet (Meleda), Croatia. Dermatology 205:32-39.
2. Barac L, Pericic M, Klaric IM, Rootsi S, Janicijevic B, Kivisild T, Parik J, Rudan I, Villems R, Rudan P. 2003. Y chromosomal heritage of Croatian population and its island isolates. Eur J Hum Genet 11:535-542.
3. Bennett LA, Angel JL, Roberts DF, Rudan P. 1983. Joint study of biological and cultural variation in Dalmatian village populations-project description. Coll Antropol 7:195-198.
4. Bersaglieri T, Sabeti PC, Patterson N, Vanderploeg T, Schaffner SF, Drake JA, Rhodes M, Reich DE, Hirschhorn JN. 2004. Genetic signatures of strong recent positive selection at the lactase gene. Am J Hum Genet 74:1111-1120.
5. Borot N, Arnaud J, Rudan P, Chaventre A, Sevin J. 1991. Phosphoglucomutase-1 subtypes in 2 populations in Adriatic Islands-presence of Pgm1-Star-W3 (Pgm1-Star-7+) allele. Hum Hered 41:309-315.
6. Burton PR, Clayton DG, Cardon LR, Craddock N, Deloukas P, Duncanson A, Kwiatkowski DP, McCarthy MI, Ouwehand WH, Samani NJ, Todd JA, Donnelly P, Barrett JC, Davison D, Easton D, Evans D, Leung HT, Marchini JL, Morris AP, Spencer CCA, Tobin MD, Attwood AP, Boorman JP, Cant B, Everson U, Hussey JM, Jolley JD, Knight AS, Koch K, Meech E, Nutland S, Prowse CV, Stevens HE, Taylor NC, Walters GR, Walker NM, Watkins NA, Winzer T, Jones RW, McArdle WL, Ring SM, Strachan DP, Pembrey M, Breen G, St Clair D, Caesar S, Gordon-Smith K, Jones L, Fraser C, Green EK, Grozeva D, Hamshere ML, Holmans PA, Jones IR, Kirov G, Moskvina V, Nikolov I, O'Donovan MC, Owen MJ, Collier DA, Elkin A, Farmer A, Williamson R, McGuffin P, Young AH, Ferrier IN, Ball SG, Balmforth AJ, Barrett JH, Bishop DT, Iles MM, Maqbool A, Yuldasheva N, Hall AS, Braund PS, Dixon RJ, Mangino M, Stevens S, Thompson JR, Bredin F, Tremelling M, Parkes M, Drummond H, Lees CW, Nimmo ER, Satsangi J, Fisher SA, Forbes A, Lewis CM, Onnie CM, Prescott NJ, Sanderson J, Mathew CG, Barbour J, Mohiuddin MK, Todhunter CE, Mansfield JC, Ahmad T, Cummings FR, Jewell DP, Webster J, Brown MJ, Lathrop GM, Connell J, Dominiczak A, Marcano CAB, Burke B, Dobson R, Gungadoo J, Lee KL, Munroe PB, Newhouse SJ, Onipinla A, Wallace C, Xue MZ, Caulfield M, Farrall M, Barton A, Bruce IN, Donovan H, Eyre S, Gilbert PD, Hider SL, Hinks AM, John SL, Potter C, Silman AJ, Symmons DPM, Thomson W, Worthington J, Dunger DB, Widmer B, Frayling TM, Freathy RM, Lango H, Perry JRB, Shields BM, Weedon MN, Hattersley AT, Elliott KS, Groves CJ, Lindgren CM, Rayner NW, Timpson NJ, Zeggini E, Newport M, Sirugo G, Lyons E, Vannberg F, Brown MA, Franklyn JA, Heward JM, Simmonds MJ, Hill AVS, Bradbury LA, Farrar C, Pointon JJ, Wordsmith P, Gough SCL, Seal S, Stratton MR, Rahman N, Ban M, Goris A, Sawcer SJ, Compston A, Conway D, Jallow M, Bumpstead SJ, Chaney A, Downes K, Ghori MJR, Gwilliam R, InouyeM, Keniry A, King E, McGinnis R, Potter S, Ravindrarajah R, Whittaker P, Withers D, Easton D, Pereira-Gale J, Hallgrimsdottir IB, Howie BN, Su Z, Teo YY, Vukcevic D, Bentley D, Caulfield M, Mathew CG, Worthington J, Wellcome Trust Case Control Consortium, Biol RA Genet & Genom Study Syndicate, Breast Canc SC. 2007. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447:661-678.
7. R Development Core Team. 2008. R: A Language and Environment for Statistical Computing. Vienna, Austria.
8. Gibson J, Morton NE, Collins A. 2006. Extended tracts of homozygosity in outbred human populations. Hum Mol Genet 15:789-795.
9. Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MAR, Bender D, Maller J, Sklar P, de Bakker PIW, Daly MJ, Sham PC. 2007. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 81:559-575.
10. Rudan I, Campbell H, Rudan P. 1999. Genetic epidemiological studies of Eastern Adriatic island isolates, Croatia: objectives and strategies. CollAntropol 23:531-546.
11. Rudan P, Sujoldzic A, Simic D, Bennett LA, Roberts DF. 1992. Population-structure in the Eastern Adriatic - the influence of historical processes, migration patterns, isolation and ecological pressures, and their interaction. Isolation Migration Health 33:204-218.
12. Saftic V, Rudan D, Zgaga L. 2006. Mendelian diseases and conditions in Croatian island populations: historic records and new insights. Croat Med J 47:543-552.
13. Service S, DeYoung J, Karayiorgou M, Roos JL, Pretorious H, Bedoya G, Ospina J, Ruiz-Linares A, Macedo A, Palha JA, Heutink P, Aulchenko Y, Oostra B, van Duijn C, Jarvelin MR, Varilo T, Peddle L, Rahman P, Piras G, Monne M, Murray S, Galver L, Peltonen L, Sabatti C, Collins A, Freimer N. 2006. Magnitude and distribution of linkage disequilibrium in population isolates and implications for genome-wide association studies. Nat Genet 38:556-560.
14. Tenesa A, Navarro P, Hayes BJ, Duffy DL, Clarke GM, Goddard ME, Visscher PM. 2007. Recent human effective population size estimated from linkage disequilibrium. Genome Res 17:520-526.
15. Thompson EE, Sun Y, Nicolae D, Ober C. 2009. Shades of gray: a comparison of linkage disequilibrium between Hutterites and Europeans. Genetic Epidemiology, DOI: 10.1002/gepi.20442.
16. Tolk HV, Barac L, Pericic M, Klaric IM, Janicijevic B, Campbell H, Rudan I, Kivisild T, Villems R, Rudan P. 2001. The evidence of mtDNA haplogroup F in a European population and its ethnohistoric implications. Eur J Hum Genet 9:717-723.
17. Turcinov D, Krishnamoorthy R, Janicijevic B, Markovic I, Mustac M, Lapoumeroulie C, Chaventre A, Rudan P. 2000. Anthropogenetical analysis of abnormal human alpha-globin gene cluster arrangement on chromosome 16. Coll Antropol 24:295-301.
18. Van Hout CV, Levin AM, Rampersaud E, Shen H, O'Connell J, Mitchell BD, Shuldiner AR, Douglas JA. 2009. Extent and distribution of linkage disequilibrium in the old order Amish. Genetic Epidemiology, DOI: 10.1002/gepi.20444.
19. Vitart V, Biloglav Z, Hayward C, Janicijevic B, Smolej-Narancic N, Barac L, Pericic M, Klaric IM, Skaric-Juric T, Barbalic M, Polasek O, Kolcic I, Carothers A, Rudan P, Hastie N, Wright A, Campbell H, Rudan I. 2006. 3000 years of solitude: extreme differentiation in the island isolates of Dalmatia, Croatia. Eur J Hum Genet 14:478-487.
20. Vitart V, Rudan I, Hayward C, Gray NK, Floyd J, Palmer CN, Knott SA, Kolcic I, Polasek O, Graessler J, Wilson JF, Marinaki A, Riches PL, Shu X, Janicijevic B, Smolej-Narancic N, Gorgoni B, Morgan J, Campbell S, Biloglav Z, Barac-Lauc L, Pericic M, Klaric IM, Zgaga L, Skaric-Juric T, Wild SH, Richardson WA, Hohenstein P, Kimber CH, Tenesa A, Donnelly LA, Fairbanks LD, Aringer M, McKeigue PM, Ralston SH, Morris AD, Rudan P, Hastie ND, Campbell H, Wright AF. 2008. SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout. Nat Genet 40:437-442.
21. Weir BS, Cardon LR, Anderson AD, Nielsen DM, Hill WG. 2005. Measures of human population structure show heterogeneity among genomic regions. Genome Res 15:1468-1476.
22. Wigginton JE, Cutler DJ, Abecasis GR. 2005. A note on exact tests of Hardy-Weinberg equilibrium. Am J Hum Genet 76:887-893.
23. Wright AF, Carothers AD, Pirastu M. 1999. Population choice in mapping genes for complex diseases. Nat Genet 23:397-404.
24. Wright S. 1978. Evolution and the Genetics of Populations. Variability Within and Among Natural Populations. Chicago, IL, USA: University of Chicago Press.