Effects of labetalol on hemodynamic parameters and soluble biomarkers of inflammation in acute coronary syndrome in patients with active cocaine use

Journal of Cardiovascular Pharmacology and Therapeutics

Volumn 15, Issue 1, 2010, Pages 47-52

  Hoskins, Michael H ^a   Leleiko, Rebecca M ^a   Ramos, Julie J ^a   Sola, Srikanth ^a   Caneer, Patrick M ^a   Khan, Bobby V ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

blocker; Acute coronary syndrome; Cocaine; Ischemia

Indexed keywords

BIOLOGICAL MARKER; CD40 LIGAND; CHOLINE; COCAINE; CREATINE KINASE; CREATININE; DILTIAZEM; GLUCOSE; HIGH DENSITY LIPOPROTEIN; INTERLEUKIN 6; LABETALOL; LOW DENSITY LIPOPROTEIN; TRIACYLGLYCEROL; TROPONIN;

ACUTE CORONARY SYNDROME; ADULT; ARTICLE; CARDIAC PATIENT; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIASTOLIC BLOOD PRESSURE; DRUG EFFECT; ECHOCARDIOGRAPHY; FEMALE; GLUCOSE BLOOD LEVEL; HEART MOVEMENT; HEART RATE; HOSPITALIZATION; HUMAN; INFLAMMATION; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL; URINALYSIS;

ACUTE CORONARY SYNDROME; ADRENERGIC ALPHA-ANTAGONISTS; ADULT; AGED; BIOLOGICAL MARKERS; CARDIOVASCULAR AGENTS; CD40 LIGAND; COCAINE-RELATED DISORDERS; DILTIAZEM; FEMALE; GEORGIA; HEMODYNAMICS; HUMANS; INFLAMMATION; INTERLEUKIN-6; LABETALOL; MALE; MIDDLE AGED; TREATMENT OUTCOME;

EID: 76649121168     PISSN: 10742484     EISSN: 19404034     Source Type: Journal    
DOI: 10.1177/1074248409358409     Document Type: Article

References (20)

1. National Institute of Drug Abuse. National household survey on drug abuse: prevalence estimates 2003. http://oas.samhsa.gov. Accessed August 12, 2005.
2. Hollander JE, Todd KH, Green G., et al. Chest pain associated with cocaine: an assessment of prevalence in suburban and urban emergency departments. Ann Emerg Med. 1995 ; 26 (6). 671-676.
3. Mittleman MA, Mintzer D., Maclure M., Tofler GH, Sherwood JB, Muller JE Triggering of myocardial infarction by cocaine. Circulation. 1999 ; 99 (21). 2737-2741.
4. Kloner RA, Rezkallah SH Cocaine and the heart. NEJM. 2003 ; 248 (6). 487-488.
5. Erwin MB, Hoyle JR, Smith CH, Deliargyris EN Cocaine and accelerated atherosclerosis: insights from intravascular ultrasound. Int J Cardiol. 2004 ; 93 (3). 301-303.
6. Havranek EP, Nademanee K., Grayburn PA, Eichhorn EJ Endothelium dependent vasorelaxation is impaired in cocaine arteriopathy. J Am Coll Cardiol. 1996 ; 28 (5). 1168-1174.
7. Qingyi M., Lima JA, Lai H., et al. Elevated C-reactive protein levels are associated with endothelial dysfunction in chronic cocaine users. Int J Cardiol. 2003 ; 88 (2-3). 191-198.
8. Anderson JL, Adams CD, Antman EM, et al. ACC/AHA 2007 guidelines for the management of patients with unstable angina/ Non-ST-segment elevation myocardial infarction. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on the Management of Patients with Unstable Angina/ Non-ST-segment elevation myocardial infarction). J Am Coll Cardiol. 2007 ; 50 (7). e1 - e157.
9. Leikin JB Cocaine and beta adrenergic blockers: a remarriage after a decade-long divorce ? Crit Care Med. 1999 ; 27 (4). 688-689.
10. Hollander JE The management of cocaine-associated myocardial ischemia. N Engl J Med. 1995 ; 333 (19). 1267-1272.
11. Ramoska E., Sacchetti AD Propranolol-induced hypertension in treatment of cocaine intoxication. Ann Emerg Med. 1985 ; 14 (11). 1112-1113.
12. Lange RA, Cigarroa RG, Flores RG, et al. Potentiation of cocaine-induced coronary vasoconstriction by beta-adrenergic blockade. Ann Intern Med. 1990 ; 112 (12). 897-903.
13. Gay GR, Lopez KA The use of labetalol in the management of cocaine crisis. Ann Emerg Med. 1988 ; 17 (3). 282-283.
14. Merigian KS, Park LJ, Leeper KV, Browning RG, Giometi R. Adrenergic crisis from crack cocaine ingestion: report of five cases. J Emerg Med. 1994 ; 12 (4). 485-490.
15. Biasucci LM, Liuzzo G., Fantuzzi G., et al. Increasing levels of interleukin (IL)-1Ra and IL-6 during the first 2 days of hospitalization in unstable angina are associated with increased risk of in-hospital coronary events. Circulation. 1999 ; 99 (16). 2079-2084.
16. Brody DL, Slovis CM, Wrenn KD Cocaine-related medical problems: consecutive series of 233 patients. Am J Med. 1990 ; 88 (4). 325-331.
17. Sand IC, Brody DL, Wrenn KD, Slovis CM Experience with esmolol for the treatment of cocaine-associated cardiovascular complications. Am J Emerg Med. 1991 ; 9 (2). 161-163.
18. Boehrer JD, Moliterno DJ, Willard JE, Hillis LD, Lange RA Influence of labetalol on cocaine-induced coronary vasoconstriction in humans. Am J Med. 1993 ; 94 (6). 608-610.
19. Blake GJ, Ridker PM C-reactive protein and other inflammatory risk markers in acute coronary syndromes. JACC. 2003 ; 41: 37S - 42S.
20. Weber M., Hamm C. Novel biomarkers-the long march from bench to bedside. Eur Heart J. 2008 ; 29 (9). 1079-1081.