Oxidative stress in the pathogenesis of abdominal aortic aneurysms: A possible pathway for the effect of statins?

Angiology

Volumn 61, Issue 2, 2010, Pages 226-227

  Paraskevas, Kosmas I ^a   Andrikopoulou, Maria ^b   Anastasakis, Eleftherios ^c   Perrea, Despina ^b   Mikhailidis, Dimitri P ^d  

^a RED CROSS HOSPITAL   (Greece)

^b UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^c ATHENS NAVAL HOSPITAL   (Greece)

^d ROYAL FREE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; REACTIVE OXYGEN METABOLITE;

ABDOMINAL AORTA ANEURYSM; ALLELE; APOPTOSIS; DNA POLYMORPHISM; DRUG EFFECT; GENOTYPE; HOMOZYGOTE; LETTER; MORBIDITY; MORTALITY; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PROTEIN DEGRADATION;

AORTIC ANEURYSM, ABDOMINAL; GENE FREQUENCY; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; NITRIC OXIDE SYNTHASE TYPE III; OXIDATIVE STRESS; POLYMORPHISM, GENETIC;

EID: 76649120535     PISSN: 00033197     EISSN: None     Source Type: Journal    
DOI: 10.1177/0003319709353168     Document Type: Letter

References (11)

1. Atli FH, Manduz S., Katrancioglu N., et al. eNOS G894T polymorphism and abdominal aortic aneurysms. Angiology. 2009 [Epub ahead of print].
2. McCormick ML, Gavrila D., Weintraub NL Role of oxidative stress in the pathogenesis of abdominal aortic aneurysms. Arterioscler Thromb Vasc Biol. 2007 ; 27 (3). 461-469.
3. Miller FJ Jr, Sharp WJ, Fang X., Oberley LW, Oberley TD, Weintraub NL Oxidative stress in human abdominal aortic aneurysms: a potential mediator of aneurysmal remodeling. Arterioscler Thromb Vasc Biol. 2002 ; 22 (4). 560-565.
4. Xiong W., Mactaggart J., Knispel R., et al. Inhibition of reactive oxygen species attenuates aneurysm formation in a murine model. Atherosclerosis 2009; 202 (1). 128-134.
5. Paraskevas KI, Tzovaras AA, Briana DD, Mikhailidis DP Emerging indications for statins: a pluripotent family of agents with several potential applications. Curr Pharm Des. 2007 ; 13 (35). 3622-3636.
6. Athyros VG, Kakafika AI, Tziomalos K., Karagiannis A., Mikhailidis DP Pleiotropic effects of statins-clinical evidence. Curr Pharm Des. 2009; 15 (5). 479-489.
7. Steinmetz EF, Buckley C., Shames ML, et al. Treatment with simvastatin suppresses the development of experimental abdominal aortic aneurysms in normal and hypercholesterolemic mice. Ann Surg. 2005 ; 241 (1). 92-101.
8. Kalyanasundaram A., Elmore JR, Manazer JR, et al. Simvastatin suppresses experimental aortic aneurysm expansion. J Vasc Surg. 2006 ; 43 (1). 117-124.
9. Paraskevas KI, Liapis CD, Hamilton G., Mikhailidis DP Are statins an option in the management of abdominal aortic aneurysms ? Vasc Endovascular Surg. 2008 ; 42 (2). 128-134.
10. Paraskevas KI, Liapis CD, Hamilton G., Mikhailidis DP Can statins reduce perioperative morbidity and mortality in patients undergoing non-cardiac vascular surgery ? Eur J Vasc Endovasc Surg. 2006 ; 32 (3). 286-293.
11. Saratzis A., Saratzis N., Melas N., Kiskinis D. Pharmacotherapy before and after endovascular repair of abdominal aortic aneurysms. Curr Vasc Pharmacol. 2008 ; 6 (4). 240-249.