Protein interactions and ligand binding: From protein subfamilies to functional specificity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 5, 2010, Pages 1995-2000

  Rausell, Antonio ^a   Juan, David ^a   Pazos, Florencio ^b   Valencia, Alfonso ^a  

^a Centro Nacional de Investigaciones Oncológicas   (Spain)

^b CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

Author keywords

Functional residues; Protein family evolution; Protein function; Protein protein interfaces; Specificity determining positions

Indexed keywords

LIGAND; PROTEIN;

ARTICLE; BINDING SITE; COMPLEX FORMATION; CONTROLLED STUDY; LIGAND BINDING; MOLECULAR EVOLUTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN INTERACTION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; BIOPHYSICAL PHENOMENA; CONSERVED SEQUENCE; DATABASES, PROTEIN; EVOLUTION, MOLECULAR; HUMANS; LIGANDS; MODELS, MOLECULAR; MULTIPROTEIN COMPLEXES; PROTEIN CONFORMATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 76649113438     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0908044107     Document Type: Article

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