Antimicrobials utilization and outcomes of neonatal sepsis among patients admitted to a University Teaching Hospital in Malaysia

Eastern Journal of Medicine

Volumn 12, Issue 1-2, 2007, Pages 6-14

  Awaisu, Ahmed ^a   Sulaiman, Syed Azhar Syed ^a   Ibrahim, Mohamed Izham Mohamed ^a   Saad, Abdulmumin ^a  

^a SCHOOL OF PHARMACEUTICAL SCIENCES   (Malaysia)

Author keywords

Antibiotics utilization; Clinical characteristics; Neonatal sepsis; NICU

Indexed keywords

EID: 76649096718     PISSN: 13010883     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Klein JO, Mercy SM. Bacterial Sepsis disease and meningitis. In Remington JS, Klein JO, eds. Infectious diseases of the fetus and newborn infants. Philadelphia: Saunders, 1990: 601- 656.
2. nd edn. New Delhi: Sagar Publication, 1995: pp 115.
3. Polin RA. The "Ins and Outs" of Neonatal Sepsis. The J of pediatrics 2003; 143: 3-4.
4. Escobar GJ. The neonatal "sepsis work - up": Personal reflections on the development of an evidence - based approach toward newborn infections in a managed care organization. Pediatrics 1999; 103: 360-373.
5. Jaswal RS, Kaushal RK, Goel A. et al. Role of C - reactive protein in deciding duration of antibiotic therapy in neonatal septicemia. Indian Pediatrics 2003; 40: 880 - 883.
6. Dowodu A, Al-Umran K, Twun-Danso K. A case control study of neonatal sepsis: experience from Saudi Arabia. J Trop Pediatr 1997; 43: 84-88.
7. Fish DN. Optimal Antimicrobial therapy for sepsis. Am J Health - Syst Pharm 2002; 59: S13-19.
8. Bochud PY, Glauser MP, Calandra T. Antibiotics in sepsis. Intensive Care Med. 2001; 27: S33 - 48.
9. Simon D, Tranholma G. Antibiotic selection for patients with septic shock. Crit Care Clin. 2000; 16: 215-231.
10. Kollef MH, Sherma G, Ward S. Inadequate antimicrobial treatment of infection. Chest 1999; 115: 462-474.
11. Anwar SK, Mustafa S, Pariyani S, Ashraf S, Taufiq KM. Neonatal sepsis: an etiological study. J Pak. Med Assoc 2000; 50 (3): 91-94.
12. Singh SA, Dutta S, Narang A. Predictive clinical scores for diagnosis of late onset neonatal septicemia. J Trop Pediatr 2003; 49: 235-239.
13. Fanaroff A, Sheldon B, Wright LL, et al. Incidence, presenting feature, risk factors, and significance of late onset septicemia. Pediatr Infect Dis J 1998; 17: 593-598.
14. Gerdes JS, Polin R. Early diagnosis and treatment of neonatal sepsis. Ind J Pediatr 1998; 65: 63 - 78.
15. Aggarwal R, Sarkar N, Deorari AK, Paul VK. Sepsis in the newborn. Indian J Pediatr 2001; 68:1143-1147.
16. Squire E, Favara B, Todd J. Diagnosis of neonatal bacterial infection: hematologic and pathologic findings in fatal and non - fatal cases. Ped 1979; 64: 60-65.
17. Davies PA and Gothefors LA. Bacterial infections in the fetus and newborn. Philadelphia, WB Saunders, 1984.
18. Kuruvilla KA, Pillai S, Jesudason M, Jana AK. Bacterial profile of sepsis in a neonatal unit in south India. Indian Pediatr 1998; 35: 851-858.
19. Ronnestad A, Abrahamsen TG, Gaustad P, Finne PH. Blood culture isolates during 6 years in a tertiary neonatal intensive care unit. Scand J Infect Dis. 1998; 30: 245-51.
20. Baek YW, Brokat S, Padbury JF et al. Inter - α inhibitor proteins in infants and decreased levels in neonatal sepsis. J. Pediatr 2003; 143: 11-15.
21. Benitz WE. Serial serum C - reactive protein determinations in the diagnosis of neonatal infections. Pediatrics 1998; 102: E41 - 55.
22. Dollner V, Austgulen H, Vatten L, Austgulen R. (2001) Early diagnostic markers for neonatal sepsis: comparing C-reactive protein, interleukin-6, soluble tumour necrosis factor receptors and soluble adhesion molecules. J Clin Epidemiol. 2001; 54: 1251-1257.
23. Pulliam PN, Attia MW, Cronan KM. C - reactive protein in febrile children 1 - 36 months of age with clinically undetectable serious bacterial infection. Pediatrics 2001; 108: 1275 - 1279.
24. Yurdokok M. Antibiotics use in neonatal sepsis. Turk J Pediatr 1998; 40: 17-33.
25. Orrett FA, Shurland SM. Neonatal sepsis and mortality in a regional hospital in Trinidad: aetiology and risk factors. Ann Trop Paediatr 2001; 21: 20-36.
26. Guidelines on Rational Antibiotic Utilisation in Selected Paediatric Conditions, Ministry of Health, Malaysia 2004.
27. Edwards MS. Q & A: Antibiotic Therapy of neonates with bacterial sepsis. Ped Infect Dis Journal 1995; 14: 166-167.
28. Klepser DG. Pitfalls associated with commonly used methods for Pharmacoeconomic analyses. Pharmacotherapy 2002; 22: 35S-38S.