-
1
-
-
23644442893
-
Tocilizumab inhibits signal transduction mediated by both mIL-6R and sIL-6R, but not by the receptors of other members of IL-6 cytokine family
-
DOI 10.1016/j.intimp.2005.05.010, PII S1567576905001360
-
M Mihara K Kasutani M Okazaki A Nakamura S Kawai M Sugimoto, et al. 2005 Tocilizumab inhibits signal transduction mediated by both mIL-6R and sIL-6R, but not by the receptors of other members of IL-6 cytokine family Int Immunopharmacol 5 1731 1740 10.1016/j.intimp.2005.05.010 1:CAS:528: DC%2BD2MXns1Wns7Y%3D 16102523 (Pubitemid 41116745)
-
(2005)
International Immunopharmacology
, vol.5
, Issue.12
, pp. 1731-1740
-
-
Mihara, M.1
Kasutani, K.2
Okazaki, M.3
Nakamura, A.4
Kawai, S.5
Sugimoto, M.6
Matsumoto, Y.7
Ohsugi, Y.8
-
2
-
-
34447300492
-
Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): Evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab
-
DOI 10.1136/ard.2006.068064
-
N Nishimoto J Hashimoto N Miyasaka K Yamamoto S Kawai T Takeuchi, et al. 2007 Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an X-ray reader-blinded randomised controlled trial of tocilizumab Ann Rheum Dis 66 1162 1167 10.1136/ard.2006.068064 1:CAS:528:DC%2BD2sXhtVKltL7O 17485422 (Pubitemid 47309731)
-
(2007)
Annals of the Rheumatic Diseases
, vol.66
, Issue.9
, pp. 1162-1167
-
-
Nishimoto, N.1
Hashimoto, J.2
Miyasaka, N.3
Yamamoto, K.4
Kawai, S.5
Takeuchi, T.6
Murata, N.7
Van Heijde, D.D.8
Kishimoto, T.9
-
3
-
-
60149105639
-
Study of active controlled tocilizumab monotherapy for rheumatoid arthritis patients with an inadequate response to methotrexate (SATORI): Significant reduction in disease activity and serum vascular endothelial growth factor by IL-6 receptor inhibition therapy
-
10.1007/s10165-008-0125-1 1:CAS:528:DC%2BD1MXhsFKmsLk%3D 18979150
-
N Nishimoto N Miyasaka K Yamamoto S Kawai T Takeuchi J Azuma, et al. 2009 Study of active controlled tocilizumab monotherapy for rheumatoid arthritis patients with an inadequate response to methotrexate (SATORI): significant reduction in disease activity and serum vascular endothelial growth factor by IL-6 receptor inhibition therapy Mod Rheumatol 19 12 19 10.1007/s10165-008-0125- 1 1:CAS:528:DC%2BD1MXhsFKmsLk%3D 18979150
-
(2009)
Mod Rheumatol
, vol.19
, pp. 12-19
-
-
Nishimoto, N.1
Miyasaka, N.2
Yamamoto, K.3
Kawai, S.4
Takeuchi, T.5
Azuma, J.6
-
4
-
-
52149099504
-
IL-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: Results from a 24-week multicentre randomised placebo-controlled trial
-
10.1136/ard.2008.092932 1:CAS:528:DC%2BD1cXhtl2gsbbI 18625622
-
P Emery E Keystone HP Tony A Cantagrel R van Vollenhoven A Sanchez, et al. 2008 IL-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: results from a 24-week multicentre randomised placebo-controlled trial Ann Rheum Dis 67 1516 1523 10.1136/ard.2008.092932 1:CAS:528: DC%2BD1cXhtl2gsbbI 18625622
-
(2008)
Ann Rheum Dis
, vol.67
, pp. 1516-1523
-
-
Emery, P.1
Keystone, E.2
Tony, H.P.3
Cantagrel, A.4
Van Vollenhoven, R.5
Sanchez, A.6
-
5
-
-
0023945481
-
The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis
-
10.1002/art.1780310302 1:STN:280:DyaL1c7pt1Ohsg%3D%3D 3358796
-
FC Arnett SM Edworthy DA Bloch DJ McShane JF Fries NS Cooper, et al. 1988 The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis Arthritis Rheum 31 315 324 10.1002/art.1780310302 1:STN:280:DyaL1c7pt1Ohsg%3D%3D 3358796
-
(1988)
Arthritis Rheum
, vol.31
, pp. 315-324
-
-
Arnett, F.C.1
Edworthy, S.M.2
Bloch, D.A.3
McShane, D.J.4
Fries, J.F.5
Cooper, N.S.6
-
6
-
-
34447343764
-
Assessing remission in clinical practice
-
DOI 10.1093/rheumatology/kem007
-
M Mierau M Schoels G Gonda J Fuchs D Aletaha JS Smolen 2007 Assessing remission in clinical practice Rheumatology (Oxford) 46 975 979 10.1093/rheumatology/kem007 1:STN:280:DC%2BD2szhsVOjsw%3D%3D (Pubitemid 47062506)
-
(2007)
Rheumatology
, vol.46
, Issue.6
, pp. 975-979
-
-
Mierau, M.1
Schoels, M.2
Gonda, G.3
Fuchs, J.4
Aletaha, D.5
Smolen, J.S.6
-
7
-
-
0023942493
-
Interleukin-6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides
-
DOI 10.1002/art.1780310614
-
FA Houssiau JP Devogelaer J Van Damme CN de Deuxchaisnes J Van Snick 1988 Interleukin-6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides Arthritis Rheum 31 784 788 10.1002/art.1780310614 1:STN:280:DyaL1c3ltFGisA%3D%3D 3260102 (Pubitemid 18171300)
-
(1988)
Arthritis and Rheumatism
, vol.31
, Issue.6
, pp. 784-788
-
-
Houssiau, F.A.1
Devogelaer, J.-P.2
Van Damme, J.3
Nagant De Deuxchaisnes, C.4
Van Snick, J.5
-
8
-
-
0027518860
-
Serum interleukin 6 levels in rheumatoid arthritis: Correlations with clinical and laboratory indices of disease activity
-
10.1136/ard.52.3.232 1:STN:280:DyaK3s3kvFejtw%3D%3D 8484679
-
R Madhok A Crilly J Watson HA Capell 1993 Serum interleukin 6 levels in rheumatoid arthritis: correlations with clinical and laboratory indices of disease activity Ann Rheum Dis 52 232 234 10.1136/ard.52.3.232 1:STN:280:DyaK3s3kvFejtw%3D%3D 8484679
-
(1993)
Ann Rheum Dis
, vol.52
, pp. 232-234
-
-
Madhok, R.1
Crilly, A.2
Watson, J.3
Capell, H.A.4
-
9
-
-
43049162899
-
Treatment response to a second or third TNF-inhibitor in RA: Results from the South Swedish Arthritis Treatment Group Register
-
10.1093/rheumatology/ken034 1:CAS:528:DC%2BD1cXmslKhtbw%3D
-
JA Karlsson LE Kristensen MC Kapetanovic A Gülfe T Saxne P Geborek 2008 Treatment response to a second or third TNF-inhibitor in RA: results from the South Swedish Arthritis Treatment Group Register Rheumatology (Oxford) 47 507 513 10.1093/rheumatology/ken034 1:CAS:528:DC%2BD1cXmslKhtbw%3D
-
(2008)
Rheumatology (Oxford)
, vol.47
, pp. 507-513
-
-
Karlsson, J.A.1
Kristensen, L.E.2
Kapetanovic, M.C.3
Gülfe, A.4
Saxne, T.5
Geborek, P.6
-
10
-
-
0028979703
-
Tumor necrosis factor-alpha is required in the protective immune response against Mycobacterium tuberculosis in mice
-
10.1016/1074-7613(95)90001-2 1:CAS:528:DyaK2MXmsFCnurY%3D 7540941
-
JL Flynn MM Goldstein J Chan KJ Triebold K Pfeffer CJ Lowenstein, et al. 1995 Tumor necrosis factor-alpha is required in the protective immune response against Mycobacterium tuberculosis in mice Immunity 2 561 572 10.1016/1074-7613(95)90001-2 1:CAS:528:DyaK2MXmsFCnurY%3D 7540941
-
(1995)
Immunity
, vol.2
, pp. 561-572
-
-
Flynn, J.L.1
Goldstein, M.M.2
Chan, J.3
Triebold, K.J.4
Pfeffer, K.5
Lowenstein, C.J.6
-
11
-
-
0033559125
-
Structural deficiencies in granuloma formation in TNF gene-targeted mice underlie the heightened susceptibility to aerosol Mycobacterium tuberculosis infection, which is not compensated for by lymphotoxin
-
1:CAS:528:DyaK1MXhvV2ru7k%3D 10092807
-
AG Bean DR Roach H Briscoe MP France H Korner JD Sedgwick, et al. 1999 Structural deficiencies in granuloma formation in TNF gene-targeted mice underlie the heightened susceptibility to aerosol Mycobacterium tuberculosis infection, which is not compensated for by lymphotoxin J Immunol 162 3504 3511 1:CAS:528:DyaK1MXhvV2ru7k%3D 10092807
-
(1999)
J Immunol
, vol.162
, pp. 3504-3511
-
-
Bean, A.G.1
Roach, D.R.2
Briscoe, H.3
France, M.P.4
Korner, H.5
Sedgwick, J.D.6
-
13
-
-
0036745041
-
Frequency of infection in patients with rheumatoid arthritis compared with controls: A population-based study
-
10.1002/art.10524 12355475
-
MF Doran CS Crowson GR Pond WM O'Fallon SE Gabriel 2002 Frequency of infection in patients with rheumatoid arthritis compared with controls: a population-based study Arthritis Rheum 46 2287 2293 10.1002/art.10524 12355475
-
(2002)
Arthritis Rheum
, vol.46
, pp. 2287-2293
-
-
Doran, M.F.1
Crowson, C.S.2
Pond, G.R.3
O'Fallon, W.M.4
Gabriel, S.E.5
-
14
-
-
49549124746
-
Use of nonbiologic disease-modifying antirheumatic drugs and risk of infection in patients with rheumatoid arthritis
-
10.1002/art.23913 18668604
-
D Lacaille DP Guh M Abrahamowicz AH Anis JM Esdaile 2008 Use of nonbiologic disease-modifying antirheumatic drugs and risk of infection in patients with rheumatoid arthritis Arthritis Rheum 59 8 1074 1081 10.1002/art.23913 18668604
-
(2008)
Arthritis Rheum
, vol.59
, Issue.8
, pp. 1074-1081
-
-
Lacaille, D.1
Guh, D.P.2
Abrahamowicz, M.3
Anis, A.H.4
Esdaile, J.M.5
|