Adjunctive dexamethasone in meningitis: does value depend on clinical setting?

The Lancet Neurology

Volumn 9, Issue 3, 2010, Pages 229-231

  McIntyre, Peter ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; DEXAMETHASONE; PLACEBO;

ADJUVANT THERAPY; BACTERIAL MENINGITIS; CLINICAL PRACTICE; CLINICAL TRIAL; COCHRANE LIBRARY; CONSCIOUSNESS; CORTICOSTEROID THERAPY; DISABILITY; EVIDENCE BASED MEDICINE; HEALTH CARE ACCESS; HEALTH STATUS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYPERGLYCEMIA; LETTER; LIFE EXPECTANCY; LOWEST INCOME GROUP; MALAWI; MORTALITY; MYCOBACTERIUM TUBERCULOSIS; OUTCOME ASSESSMENT; PREVALENCE; PRIORITY JOURNAL; REGRESSION ANALYSIS; TREATMENT OUTCOME; UNSPECIFIED SIDE EFFECT; VIET NAM; WESTERN EUROPE;

CLINICAL TRIALS AS TOPIC; DEXAMETHASONE; DRUG THERAPY, COMBINATION; HUMANS; MENINGITIS, BACTERIAL;

EID: 76649093903     PISSN: 14744422     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1474-4422(10)70022-3     Document Type: Letter

References (11)

1. Murray C.J., Lopez A.D., Mathers C.D., and Stein C. The Global Burden of Disease 2000 project: aims, methods and data sources (2001), World Health Organization. http://www.who.int/healthinfo/paper36.pdf (accessed 18 Jan, 2010).
2. van de Beek D., de Gans J., McIntyre P., and Prasad K. Corticosteroids for acute bacterial meningitis. Cochrane Database Syst Rev 3 (2003) CD004405.
3. van de Beek D., Farrar J.J., de Gans J., et al. Adjunctive dexamethasone in bacterial meningitis: a meta-analysis of individual patient data. Lancet Neurol (2010) 10.1016/S1474-4422(10)70023-5 online publication February 4.
4. Higgins J.P.T., Thompson S.G., Deeks J.J., and Altman D.G. Measuring inconsistency in meta-analyses. Br Med J 327 (2003) 557-560
5. Molyneux E., Walsh A., Phiri A., and Molyneux M. Acute bacterial meningitis in children admitted to the Queen Elizabeth central hospital Blantyre Malawi, 1996-97. Trop Med Int Health 3 (1998) 610-618
6. Kilpi T., Anttila M., Kallio M.J.T., and Peltola H. Severity of childhood bacterial meningitis and duration of illness before diagnosis. Lancet 338 (1991) 406-409
7. Thwaites G.E., Chau T.T.H., Stepniewska K., et al. Diagnosis of adult tuberculous meningitis by use of clinical and laboratory features. Lancet 360 (2002) 1287-1292
8. Gordon S.B., Walsh A.L., Chaponda M., et al. Bacterial meningitis in Malawian adults: pneumococcal disease is common, severe and seasonal. Clin Inf Dis 31 (2000) 53-57
9. Nguyen T.H., Tran T.H., Thwaites G., et al. Dexamethasone in Vietnamese adolescents and adults with bacterial meningitis. N Engl J Med 357 (2007) 2431-2440
10. Peltola H., Roine I., Fernandez J., et al. Adjuvant glycerol and/or dexamethasone to improve the outcomes of childhood bacterial meningitis: a prospective, randomized, double-blind, placebo-controlled trial. Clin Infect Dis 45 (2007) 1277-1286
11. Korshin A., Koster-Rasmussen R., and Meyer C.N. Adjunctive steroid treatment: local guidelines and patient outcome in adult bacterial meningitis. Scand J Infect Dis 39 (2007) 963-968