Absorption and metabolism of flavonoids in Herba Epimedii via rat intestinal perfusion model

Zhongguo Zhongyao Zazhi

Volumn 34, Issue 22, 2009, Pages 2928-2931

  Chen, Yan ^a   Jia, Xiaobin ^a   Tan, Xiaobin ^a   Fan, Chenyi ^a   Hu, Ming ^b  

^a KEY LABORATORY OF NEW DRUG DELIVERY SYSTEM OF CHINESE MATERIA MEDICA   (China)

^b UNIVERSITY OF HOUSTON   (United States)

Author keywords

Absorption; Flavonoids in Herba Epimedii; Metabolism; Permeability coefficient; Rat intestinal perfusion model

Indexed keywords

BAOHUOSIDE I; EPIMEDIN A; EPIMEDIN B; EPIMEDIN C; EPIMEDIUM EXTRACT; FLAVONOID; ICARIIN; INTESTINE ENZYME; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CHEMICAL STRUCTURE; COLON; COLON ABSORPTION; DRUG ABSORPTION; DRUG HYDROLYSIS; DRUG METABOLISM; DRUG PENETRATION; DUODENUM; EPIMEDIUM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ILEUM; INTESTINE MUCOSA PERMEABILITY; INTESTINE PERFUSION; JEJUNUM; METABOLITE; NONHUMAN; RAT; SMALL INTESTINE ABSORPTION;

ABSORPTION; ANIMALS; EPIMEDIUM; FLAVONOIDS; INTESTINES; MALE; MODELS, ANIMAL; PERFUSION; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 76649090254     PISSN: 10015302     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Chinese source
2. Chinese source
3. Chinese source
4. Chinese source
5. Chinese source
6. Chen Jun, Lin Huimin, Hu Ming. Metabolism of flavonoid via enteric recycling: Role of intestinal disposition [J]. Pharmacol Exp Ther, 2003, 304 (3) : 1228.
7. Yong Liu, Yan Liu, Yang Dai, et al. Enteric disposition an recycling of flavonoids and ginkgo flavonoids [J]. Alter Complement Med, 2003, 9 (5) : 631.
8. Jeong E J, Jia X B, Hu M. Disposition of formononetin via enteric recycling: Metabolism and excretion in mouse intestinal perfusion and Caco-2 cell model[J]. Mol Pharmacol, 2005 , 2 : 319.