A "GC-rich" method for mammalian gene expression: A dominant role of non-coding DNA GC content in regulation of mammalian gene expression

Science China Life Sciences

Volumn 53, Issue 1, 2010, Pages 94-100

  Jia, Qian ^a   Wu, HongTao ^a   Zhou, XingJun ^a   Gao, Jian ^a   Zhao, Wei ^a   Aziz, JouDi ^b,d   Wei, JingShuang ^a   Hou, Lihua ^e   Wu, Shuyin ^d   Zhang, Ying ^c   Dong, XiangFeng ^a   Huang, YanMin ^a   Jin, WeiYuan ^d   Zhu, HongJie ^c   Zhao, XinHui ^e   Huang, ChunHua ^f   Xing, LiPing ^d   Li, Liwen ^d   Ma, Jun ^d   Liu, Xiyan ^d   Tao, Ran ^d   Ye, ShuaiDong ^d   Song, YiGao ^d   Song, LingLing ^d   Chen, GuanPing ^d   Du, ChunLing ^d   Zhang, XueTing ^c   Li, Bo ^c   Wang, YanTao ^c   Yang, Wei ^c   Rishton, Gilbert ^b   Teng, YuYang ^c   Leng, GouQing ^c   Li, LuanFeng ^d   Liu, WenXian ^a   Cheng, LiJun ^a   Liang, QiuBo ^c   Li, ZhengWu ^c   Zhang, XiuQin ^c   Zuo, Yajun ^f   Chen, Wei ^e   Li, Huicheng ^c   Hui, Matthew ^a,b,c,d   more..

^a NCPC R and D Center   (China)

^b AmProtein Inc   (United States)

^c Harbin Pharmaceutical Group R and D Center   (China)

^d AmProtein China   (China)

^e BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

^f Academic Sinica   (China)

Author keywords

DNA structure; Expression mechanism; GC content; GC rich; Mammalian cell; Stable expression

Indexed keywords

ACTIN; DNA; CHROMATIN;

ANIMAL; ARTICLE; CELL CULTURE; CHICKEN; CHO CELL; CHROMATIN; CRICETULUS; DNA BASE COMPOSITION; GENE EXPRESSION; GENETIC TRANSFECTION; GENETICS; HAMSTER; INTRON; MAMMAL; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; CHO CELL LINE;

ACTINS; ANIMALS; BASE COMPOSITION; BASE SEQUENCE; CELLS, CULTURED; CHICKENS; CHO CELLS; CHROMATIN; CRICETINAE; CRICETULUS; DNA; GENE EXPRESSION; INTRONS; MAMMALS; MOLECULAR SEQUENCE DATA; TRANSFECTION;

MAMMALIA;

EID: 76649086996     PISSN: 16747305     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11427-010-0003-x     Document Type: Article

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