Sensorimotor cortical activation in patients with cervical spinal cord injury with persisting paralysis

Neurorehabilitation and Neural Repair

Volumn 24, Issue 2, 2010, Pages 136-140

  Jurkiewicz, Michael T ^a,b   Mikulis, David J ^b   Fehlings, Michael G ^b   Verrier, Mary C ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b TORONTO WESTERN HOSPITAL   (Canada)

Author keywords

Cortical activation; Movement; Paralysis; Plasticity; Recovery; Serial fMRI

Indexed keywords

ADULT; ARTICLE; CASE REPORT; CERVICAL SPINAL CORD INJURY; CONTROLLED STUDY; CONVALESCENCE; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; MALE; MOTOR CORTEX; MOTOR PERFORMANCE; NERVE CELL PLASTICITY; NERVOUS SYSTEM; QUADRIPLEGIA; SENSORIMOTOR CORTEX; SPINAL PARALYSIS;

ADULT; ANKLE; BRAIN MAPPING; CASE-CONTROL STUDIES; FEMALE; FUNCTIONAL LATERALITY; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MOTOR CORTEX; OXYGEN; PARALYSIS; RECOVERY OF FUNCTION; REFLEX; SOMATOSENSORY CORTEX; SPINAL CORD INJURIES; TIME FACTORS; YOUNG ADULT;

EID: 76649084900     PISSN: 15459683     EISSN: 15526844     Source Type: Journal    
DOI: 10.1177/1545968309347680     Document Type: Article

References (19)

1. Mikulis DJ, Jurkiewicz MT, McIlroy WE, et al. Adaptation in the motor cortex following cervical spinal cord injury. Neurology. 2002 ; 58: 794-801.
2. Cramer SC, Lastra L., Lacourse MG, Cohen MJ Brain motor system function after chronic, complete spinal cord injury. Brain. 2005 ; 128: 2941-2950.
3. Turner JA, Lee JS, Martinez O., Medlin AL, Schandler SL, Cohen MJ Somatotopy of the motor cortex after long-term spinal cord injury or amputation. IEEE Trans Neural Syst Rehabil Eng. 2001 ; 9: 154-160.
4. Sabbah P., De Schonen S., Leveque C., et al. Sensorimotor cortical activity in patients with complete spinal cord injury: a functional magnetic resonance imaging study. J Neurotrauma. 2002 ; 19: 53-60.
5. Jurkiewicz MT, Mikulis DJ, McIlroy WE, Fehlings MG, Verrier MC Sensorimotor cortical plasticity during recovery following spinal cord injury: a longitudinal fMRI study. Neurorehabil Neural Repair. 2007 ; 21: 527-538.
6. Marino RJ, Barros T., Biering-Sorensen F., et al. International standards for neurological classification of spinal cord injury. J Spinal Cord Med. 2003 ; 26 (suppl 1). S50 - S56.
7. Marino RJ, Graves DE Metric properties of the ASIA motor score: subscales improve correlation with functional activities. Arch Phys Med Rehabil. 2004 ; 85: 1804-1810.
8. Little JW, Ditunno JF Jr, Steins SA, Harris RM Incomplete spinal cord injury: neuronal mechanisms of motor recovery and hyperreflexia. Arch Phys Med Rehabil. 1999 ; 80: 587-599.
9. Waters RL, Adkins RH, Yakura JS, Sie I. Motor and sensory recovery following complete tetraplegia. Arch Phys Med Rehabil. 1993 ; 74: 242-247.
10. Jurkiewicz M., McIlroy W., Verrier M., Mikulis D. Serial fMRI of the tongue and wrist motor cortex: reproducibility of cortical activation. Neuroimage. 2003 ; 19: S51.
11. Talairach J., Tournoux P. Co-planar Stereotactic Atlas of the Human Brain. New York, NY: Thieme Medical Publishers ; 1998.
12. Ciccarelli O., Toosy AT, Marsden JF, et al. Identifying brain regions for integrative sensorimotor processing with ankle movements. Exp Brain Res. 2005 ; 166: 31-42.
13. MacIntosh BJ, Mraz R., Baker N., Tam F., Staines WR, Graham SJ Optimizing the experimental design for ankle dorsiflexion fMRI. Neuroimage. 2004 ; 22: 1619-1627.
14. Holly LT, Dong Y., Albistegui-DuBois R., Marehbian J., Dobkin B. Cortical reorganization in patients with cervical spondylotic myelopathy. J Neurosurg Spine. 2007 ; 6: 544-551.
15. Yoo SS, Wei X., Dickey CC, Guttmann CRG, Panych LP Long-term reproducibility analysis of fMRI using hand motor task. Int J Neurosci. 2005 ; 115: 55-77.
16. Liepert J., Tegenthoff M., Malin J. -P. Changes of cortical motor area size during immobilization. Electroencephalogr Clin Neurophysiol. 1995 ; 97: 382-386.
17. Crawley AP, Jurkiewicz MT, Yim A., et al. Absence of localized grey matter volume changes in the motor cortex following spinal cord injury. Brain Res. 2004 ; 1028: 19-25.
18. Corbetta M., Burton H., Sinclair RJ, Conturo TE, Akbudak E. Functional reorganization and stability of somatosensory-motor cortical topography in a tetraplegic subject with late recovery. Proc Natl Acad Sci U S A. 2002 ; 99: 17066-17071.
19. Lotze M., Laubis-Herrmann U., Topka H., Erb M., Grodd W. Reorganization in the primary motor cortex after spinal cord injury: a functional magnetic resonance (fMRI) study. Restor Neurol Neurosci. 1999 ; 14: 183-187.