Phosphatidylethanolamine synthesized by four different pathways is supplied to the plasma membrane of the yeast Saccharomyces cerevisiae

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1801, Issue 4, 2010, Pages 480-486

  Schuiki, Irmgard ^a   Schnabl, Martina ^a   Czabany, Tibor ^a   Hrastnik, Claudia ^a   Daum, Günther ^a  

^a GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

Author keywords

Fatty acid; Phosphatidylethanolamine; Phospholipid; Plasma membrane; Yeast

Indexed keywords

ACYL COENZYME A; ETHANOLAMINE; FATTY ACID; PHOSPHATIDYLETHANOLAMINE; PHOSPHATIDYLSERINE; PHOSPHATIDYLSERINE DECARBOXYLASE; PHOSPHATIDYLSERINE DECARBOXYLASE 1; PHOSPHATIDYLSERINE DECARBOXYLASE 2; PHOSPHOETHANOLAMINE; PHOSPHOLIPID; SPHINGOLIPID; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; BIOGENESIS; CATALYSIS; CELL MEMBRANE; DECARBOXYLATION; ENDOPLASMIC RETICULUM; GENE DELETION; LIPID ANALYSIS; MITOCHONDRION; MUTANT; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SACCHAROMYCES CEREVISIAE; WILD TYPE; YEAST;

CARBOXY-LYASES; CELL MEMBRANE; ENDOPLASMIC RETICULUM; GOLGI APPARATUS; MUTATION; PHOSPHATIDYLETHANOLAMINES; SACCHAROMYCES CEREVISIAE;

SACCHAROMYCES CEREVISIAE;

EID: 76549105133     PISSN: 13881981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbalip.2009.12.008     Document Type: Article

References (43)

1. Daum G., and Vance J.E. Import of lipids into mitochondria. Prog. Lipid Res. 36 (1997) 103-130
2. Leber A., Hrastnik C., and Daum G. Phospholipid-synthesizing enzymes in Golgi membranes of the yeast, Saccharomyces cerevisiae. FEBS Lett. 377 (1995) 271-274
3. Trotter P.J., and Voelker D.R. Lipid transport processes in eukaryotic cells. Biochim. Biophys. Acta 1213 (1994) 241-262
4. Zinser E., Sperka-Gottlieb C.D.M., Fasch E.-V., Kohlwein S.D., Paltauf F., and Daum G. Phospholipid synthesis and lipid composition of subcellular membranes in the unicellular eukaryote Saccharomyces cerevisiae. J. Bacteriol. 173 (1991) 2026-2034
5. Birner R., and Daum G. Biogenesis and cellular dynamics of aminoglycerophospholipids. Int. Rev. Cytol. 225 (2003) 273-323
6. Daum G., Lees N.D., Bard M., and Dickson R. Biochemistry, cell biology and molecular biology of lipids of Saccharomyces cerevisiae. Yeast 14 (1998) 1471-1510
7. Voelker D.R. Genetic analysis of intracellular aminoglycerophospholipid traffic. Biochem. Cell. Biol. 82 (2004) 165-169
8. Trotter P.J., and Voelker D.R. Identification of a non-mitochondrial phosphatidylserine decarboxylase activity in the yeast Saccharomyces cerevisiae. J. Biol. Chem. 270 (1995) 6062-6070
9. Kennedy E.P., and Weiss S.B. The function of cytidine coenzymes in the biosynthesis of phospholipids. J. Biol. Chem. 222 (1956) 193-214
10. Riekhof W.R., and Voelker D.R. Uptake and utilization of lyso-phosphatidylethanolamine by Saccharomyces cerevisiae. J. Biol. Chem. 281 (2006) 36588-36596
11. Riekhof W.R., Wu J., Jones J.L., and Voelker D.R. Identification and characterization of the major lysophosphatidylethanolamine acyltransferase in Saccharomyces cerevisiae. J. Biol. Chem. 282 (2007) 28344-28352
12. Gaigg B., Simbeni R., Hrastnik C., Paltauf F., and Daum G. Characterization of a microsomal subfraction associated with mitochondria of the yeast, Saccharomyces cerevisiae. Involvement in synthesis and import of phospholipids into mitochondria. Biochim. Biophys. Acta 1234 (1995) 214-220
13. Kuchler K., Daum G., and Paltauf F. Subcellular and submitochondrial localization of phospholipid-synthesizing enzymes in Saccharomyces cerevisiae. J. Bacteriol. 165 (1986) 901-910
14. Gottlieb D., Heideman W., and Saba J.D. The DPL1 gene is involved in mediating the response to nutrient deprivation in Saccharomyces cerevisiae. Mol. Cell. Biol. Res. Commun. 1 (1999) 66-71
15. Saba J.D., Nara F., Bielawska A., Garrett S., and Hannun Y.A. The BST1 gene of Saccharomyces cerevisiae is the sphingosine-1-phosphate lyase. J. Biol. Chem. 272 (1997) 26087-26090
16. Sherman F., Fink G., and Hicks J. Methods in yeast genetics: a laboratory course manual (1986), Cold Spring Harbor, NY
17. Birner R., Bürgermeister M., Schneiter R., and Daum G. Roles of phosphatidylethanolamine and of its several biosynthetic pathways in Saccharomyces cerevisiae. Mol. Biol. Cell 12 (2001) 997-1007
18. Longtine M.S., McKenzie A., Demarini D.J., Shah N.G., Wach A., Brachat A., Philippsen P., and Pringle J.R. Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae. Yeast 14 (1998) 953-961
19. Gietz D., St.Jean A., Woods R.A., and Schiestl R.H. Improved method for high efficiency transformation of intact yeast cells. Nucleic Acids Res. 20 (1992) 1425
20. +-ATPase from plasma membranes of Saccharomyces cerevisiae and Avena sativa roots: purification and reconstitution. Methods Enzymol. 157 (1988) 523-544
21. van den Hazel H.B., Pichler H., do Valle Matta M.A., Leitner E., Goffeau A., and Daum G. PDR16 and PDR17, two homologous genes of Saccharomyces cerevisiae, affect lipid biosynthesis and resistance to multiple drugs. J. Biol. Chem. 274 (1999) 1934-1941
22. Pichler H., Gaigg B., Hrastnik C., Achleitner G., Kohlwein S.D., Zellnig G., Perktold A., and Daum G. A subfraction of the yeast endoplasmic reticulum associates with the plasma membrane and has a high capacity to synthesize lipids. Eur. J. Biochem. 268 (2001) 2351-2361
23. Lowry O.H., Rosebrough N.J., Farr A.L., and Randall R.J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193 (1951) 265-275
24. Folch J., Lees M., and Sloane Stanley G.H. A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 226 (1957) 497-509
25. Broekhuyse R.M. Phospholipids in tissues of the eye. I. Isolation, characterization and quantitative analysis by two-dimensional thin-layer chromatography of diacyl and vinyl-ether phospholipids. Biochim. Biophys. Acta 152 (1968) 307-315
26. Morrison W.R., and Smith L.M. Preparation of fatty acid methyl esters and dimethylacetals from lipids with boron fluoride-methanol. J. Lipid Res. 53 (1964) 600-608
27. Zinser E., and Daum G. Isolation and biochemical characterization of organelles from the yeast. Yeast 11 (1995) 493-536
28. Birner R., Nebauer R., Schneiter R., and Daum G. Synthetic lethal interaction of the mitochondrial phosphatidylethanolamine biosynthetic machinery with the prohibitin complex of Saccharomyces cerevisiae. Mol. Biol. Cell 14 (2003) 370-383
29. Bürgermeister M., Birner-Grünberger R., Nebauer R., and Daum G. Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae. Biochim. Biophys. Acta 1686 (2004) 161-168
30. Gohil V.M., Thompson M.N., and Greenberg M.L. Synthetic lethal interaction of the mitochondrial phosphatidylethanolamine and cardiolipin biosynthetic pathways in Saccharomyces cerevisiae. J. Biol. Chem. 280 (2005) 35410-35416
31. Nebauer R., Schuiki I., Kulterer B., Trajanoski Z., and Daum G. The phosphatidylethanolamine level of yeast mitochondria is affected by the mitochondrial components Oxa1p and Yme1p. FEBS J. 274 (2007) 6180-6190
32. Storey M.K., Clay K.L., Kutateladze T., Murphy R.C., Overduin M., and Voelker D.R. Phosphatidylethanolamine has an essential role in Saccharomyces cerevisiae that is independent of its ability to form hexagonal phase structures. J. Biol. Chem. 276 (2001) 48539-48548
33. Opekarová M., Malínská K., Nováková L., and Tanner W. Differential effect of phosphatidylethanolamine depletion on raft proteins: further evidence for diversity of rafts in Saccharomyces cerevisiae. Biochim. Biophys. Acta 1711 (2005) 87-95
34. Opekarová M., Robl I., and Tanner W. Phosphatidylethanolamine is essential for targeting the arginine transporter Can1p to the plasma membrane of yeast. Biochim. Biophys. Acta 19 (2002) 9-13
35. Robl I., Grassl R., Tanner W., and Opekarová M. Construction of phosphatidylethanolamine-less strain of Saccharomyces cerevisiae. Effect on amino acid transport. Yeast 18 (2001) 251-260
36. Hechtberger P., Zinser E., Saf R., Hummel K., Paltauf F., and Daum G. Characterization, quantification and subcellular localization of inositol-containing sphingolipids of the yeast, Saccharomyces cerevisiae. Eur. J. Biochem. 225 (1994) 641-649
37. Schnabl M., Daum G., and Pichler H. Multiple lipid transport pathways to the plasma membrane in yeast. Biochim. Biophys. Acta 1687 (2005) 130-140
38. Baumann N.A., Sullivan D.P., Ohvo-Rekilä H., Simonot C., Pottekat A., Klaassen Z., Beh C.T., and Menon A.K. Transport of newly synthesized sterol to the sterol-enriched plasma membrane occurs via nonvesicular equilibration. Biochemistry 44 (2005) 5816-5826
39. Sullivan D.P., Ohvo-Rekilä H., Baumann N.A., Beh C.T., and Menon A.K. Sterol trafficking between the endoplasmic reticulum and plasma membrane in yeast. Biochem. Soc. Trans. 34 (2006) 356-358
40. Holthuis J.C.M., and Levine T. Lipid traffic: floppy drives and a superhighway. Nat. Rev. Mol. Cell. Biol. 6 (2005) 209-220
41. Achleitner G., Gaigg B., Krasser A., Kainersdorfer E., Kohlwein S.D., Perktold A., Zellnig G., and Daum G. Association between the endoplasmic reticulum and mitochondria of yeast facilitates interorganelle transport of phospholipids through membrane contact. Eur. J. Biochem. 264 (1999) 545-553
42. Vance J.E. Phospholipid synthesis in a membrane fraction associated with mitochondria. J. Biol. Chem. 265 (1990) 7248-7256
43. Kornmann B., Currie E., Collins S.R., Schuldiner M., Nunnari J., Weissman J.S., and Walter P. An ER-mitochondria tethering complex revealed by a synthetic biology screen. Science 325 (2009) 477-481