Small intestinal bacterial overgrowth Histopathologic features and clinical correlates in an underrecognized entity

Archives of Pathology and Laboratory Medicine

Volumn 134, Issue 2, 2010, Pages 264-270

  Lappinga, Paul J ^a   Abraham, Susan C ^c,d   Murray, Joseph A ^b   Vetter, Emily A ^a   Patel, Robin ^a   Wu, Tsung Teh ^a  

^a Departments of Laboratory Medicine and Pathology   (United States)

^b Departments of Laboratory Medicine and Pathology and Gastroenterology

^c MAYO CLINIC   (United States)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; BACTERIUM; BIOPSY; CHILD; DIARRHEA; FEMALE; GROWTH, DEVELOPMENT AND AGING; HUMAN; INFANT; MALE; MICROBIOLOGY; MIDDLE AGED; NEWBORN; PATHOLOGY; PRESCHOOL CHILD; SMALL INTESTINE;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BACTERIA; BIOPSY; CHILD; CHILD, PRESCHOOL; DIARRHEA; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; INTESTINE, SMALL; MALE; MIDDLE AGED;

EID: 76449114803     PISSN: 00039985     EISSN: 15432165     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Teo M, Chung S, Chitti L, et al. Small bowel bacterial overgrowth is a common cause of chronic diarrhea. J Gastroenterol Hepatol. 2004;19(8):904-909.
2. Domsic R, Fasanella K, Bielefeldt K. Gastrointestinal manifestations of systemic sclerosis. Dig Dis Sci. 2008;53(5):1163-1174.
3. Meagher AP, Porter AJ, Rowland R, Ma G, Hoffmann DC. Jejunal diverticulosis. Aust N Z J Surg. 1993;63(5):360-366.
4. Gunnarsdottir SA, Sadik R, Shev S, et al. Small intestinal motility disturbances and bacterial overgrowth in patients with liver cirrhosis and portal hypertension. Am J Gastroenterol. 2003;98(6):1362-1370.
5. Strid H, Simrén M, Stotzer PO, Ringström G, Abrahamsson H, Bjö rnsson ES. Patients with chronic renal failure have abnormal small intestinal motility and a high prevalence of small intestinal bacterial overgrowth. Digestion. 2003;67(3): 129-137.
6. Tursi A, Brandimarte G, Giorgetti GM, Elisei W. Assessment of small intestinal bacterial overgrowth in uncomplicated acute diverticulitis of the colon. World J Gastroenterol. 2005;11(18):2773-2776.
7. Lauritano EC, Bilotta AL, Gabrielli M, et al. Association between hypothyroidism and small intestinal bacterial overgrowth. J Clin Endocrinol Metab. 2007;92(11):4180-4184. (Pubitemid 350074729)
8. Resmini E, Parodi A, Savarino V, et al. Evidence of prolonged orocecal transit time and small intestinal bacterial overgrowth in acromegalic patients. J Clin Endocrinol Metab. 2007;92(6):2119-2124.
9. Mishkin D, Boston FM, Blank D, Yalovsky M, Mishkin S. The glucose breath test: a diagnostic test for small bowel stricture(s) in Crohn's disease. Dig Dis Sci. 2002;47(3):489-494.
10. dos Reis JC, de Morais MB, Oliva CA, Fagundes-Neto U. Breath hydrogen test in the diagnosis of environmental enteropathy in children living in an urban slum. Dig Dis Sci. 2007;52(5):1253-1258.
11. Fridge JL, Conrad C, Gerson L, Castillo RO, Cox K. Risk factors for small bowel bacterial overgrowth in cystic fibrosis. J Pediatr Gastroenterol Nutr. 2007; 44(2):212-218.
12. Kaufman SS, Loseke CA, Lupo JV, et al. Influence of bacterial overgrowth and intestinal inflammation on duration of parenteral nutrition in children with short bowel syndrome. J Pediatr. 1997;131(3):356-361.
13. Maestri L, Fava G, Fontana M, et al. Small bowel overgrowth: a frequent complication after abdominal surgery in newborns. Pediatr Med Chir. 2002; 24(5):374-376.
14. Elphick HL, Elphick DA, Sanders DS. Small bowel bacterial overgrowth: an underrecognized cause of malnutrition in older adults.Geriatrics. 2006;61(9):21-26.
15. Lobo B, Casellas F, de Torres I, Chicharro L, Malagelada JR. Usefulness of jejunal biopsy in the study of intestinal malabsorption in the elderly. Rev Esp Enferm Dig. 2004;96(4):259-264.
16. Mitsui T, Shimaoka K, Goto Y, et al. Small bowel bacterial overgrowth is not seen in healthy adults but is in disabled older adults. Hepatogastroenterology. 2006;53(67):82-85.
17. O'Mahony S, Shanahan F. Enteric bacterial flora and bacterial overgrowth. In: Feldman M, Friedman LS, Brandt LJ, Sleisenger MH, eds. Feldman: Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 8th ed. Philadelphia, PA: Saunders Elsevier; 2006:2247-2252.
18. Riordan SM, McIver CJ, Duncombe VM, Bolin TD. Bacteriologic analysis of mucosal biopsy specimens for detecting small-intestinal bacterial overgrowth. Scand J Gastroenterol. 1995;30(7):681-685.
19. Simrén M, Stotzer PO. Use and abuse of hydrogen breath tests. Gut. 2006; 55(3):297-303.
20. Su J, Smith MB, Rerknimitr R, Morrow D. Small intestine bacterial overgrowth presenting as protein-losing enteropathy. Dig Dis Sci. 1998;43(3):679-681.
21. 14C-xylose breath tests. Cancer Biother Radiopharm. 2007;22(6):762-771.
22. Fagundes-Neto U, De Martini-Costa S, Pedroso MZ, Scaletsky IC. Studies of the small bowel surface by scanning electron microscopy in infants with persistent diarrhea. Braz J Med Biol Res. 2000;33(12):1437-1442.
23. Riordan SM, McIver CJ, Wakefield D, Duncombe VM, Thomas MC, Bolin TD. Small intestinal mucosal immunity and morphometry in luminal overgrowth of indigenous get flora. Am J Gastroenterol. 2001;96(2):494-500.
24. Ament ME, Shimoda SS, Saunders DR, Rubin CE. Pathogenesis of steatorrhea in three cases of small intestinal stasis syndrome. Gastroenterology. 1972;63(5):728-747.
25. Haboubi NY, Lee GS, Montgomery RD. Duodenal mucosal morphometry of elderly patients with small intestinal bacterial overgrowth: response to antibiotic treatment. Age Ageing. 1991;20(1):29-32.
26. King CE, Toskes PP. Small intestine bacterial overgrowth. Gastroenterology. 1979;76(5, pt 1):1035-1055.
27. Paulley JW. Gut damage in human blind-loop syndrome. Gastroenterology. 1981;81(1):195.
28. Riordan SM, McIver CJ, Wakefield D, Duncombe VM, Bolin TD, Thomas MC. Luminal antigliadin antibodies in small intestinal bacterial overgrowth. Am J Gastroenterol. 1997;92(8):1335-1338.
29. Roberts SH, James O, Jarvis EH. Bacterial overgrowth without "blind loop": a cause for malnutrition in the elderly. Lancet. 1977;2(8050):1193-1195.
30. McEvoy A, Dutton J, James OF. Bacterial contamination of the small intestine is an important cause of occult malabsorption in the elderly. Br Med J. 1983;287(6395):789-793.
31. Donald IP, Kitchingmam G, Donald F, Kupfer RM. The diagnosis of small bowel bacterial overgrowth in elderly patients. J Am Geriatr Soc. 1992;40(7): 692-696.
32. Lewis SJ, Potts LF, Malhotra R, Mountford R. Small bowel bacterial overgrowth in subjects living in residential care homes. Age Ageing. 1999;28(2): 181-185.
33. Parlesak A, Klein B, Schecher K, Bode JC, Bode C. Prevalence of small bowel bacterial overgrowth and its association with nutrition intake in nonhospitalized older adults. J Am Geriatr Soc. 2003;51(6):768-773.
34. Posserud I, Stotzer PO, Björnsson ES, Abrahamsson H, Simrén M. Small intestinal bacterial overgrowth in patients with irritable bowel syndrome. Gut. 2007;56(6):802-808.
35. Lin HC, Pimentel M. Bacterial concepts in irritable bowel syndrome. Rev Gastroenterol Disord. 2005;5(suppl 3):S3-S9.
36. Esposito I, de Leone A, Di Gregorio G, et al. Breath test for differential diagnosis between small intestinal bacterial overgrowth and irritable bowel disease: an observation on non-absorbable antibiotics. World J Gastroenterol. 2007;13(45):6016-6021.
37. Pimentel M, Chow EJ, Lin HC. Eradication of small intestinal bacterial overgrowth reduces symptoms of irritable bowel syndrome. Am J Gastroenterol. 2000;95(12):3503-3506.
38. Majewski M, Reddymasu SC, Sostarich S, Foran P, McCallum RW. Efficacy of rifaximin, a nonabsorbed oral antibiotic, in the treatment of small intestinal bacterial overgrowth. Am J Med Sci. 2007;333(5):266-270.
39. Fagundes-Neto U, Kallas MR, Patricio FR. Morphometric study of the small bowel mucosa in infants with diarrhea due to enteropathogenic Escherichia coli strains. Hepatogastroenterology. 1997;44(16):1051-1056.
40. Tursi A, Brandimarte G, Giorgetti G. High prevalence of small intestinal bacterial overgrowth in celiac patients with persistence of gastrointestinal symptoms after gluten withdrawal. Am J Gastroenterol. 2003;98(4):839-843.