Histone code in the cross-talk during DNA damage signaling

Cell Research

Volumn 20, Issue 2, 2010, Pages 113-115

  Vaissière, Thomas ^a   Herceg, Zdenko ^a  

^a INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE; HISTONE ACETYLTRANSFERASE; HTATIP PROTEIN, HUMAN;

ANIMAL; ARTICLE; DNA DAMAGE; DOUBLE STRANDED DNA BREAK; GENETICS; HISTONE CODE; HUMAN; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; DNA BREAKS, DOUBLE-STRANDED; DNA DAMAGE; HISTONE ACETYLTRANSFERASES; HISTONE CODE; HISTONES; HUMANS; SIGNAL TRANSDUCTION;

EID: 76449099935     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2010.14     Document Type: Article

References (10)

1. Loizou JI, Murr R, Finkbeiner MG et al. Epigenetic information in chromatin: the code of entry for DNA repair. Cell Cycle 2006; 5:696-701.
2. Murr R, Loizou JI, Yang YG et al. Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks. Nat Cell Biol 2006; 8:91-99.
3. Robert F, Hardy S, Nagy Z et al. The transcriptional histone acetyltransferase cofactor TRRAP associates with the MRN repair complex and plays a role in DNA double-strand break repair. Mol Cell Biol 2006; 26:402-412.
4. Sun Y, Jiang X, Chen S, Fernandes N, Price BD. A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM. Proc Natl Acad Sci USA 2005; 102:13182-13187.
5. Sun Y, Jiang X, Xu Y et al. Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60. Nat Cell Biol 2009; 11:1376-1382.
6. Jiang X, Sun Y, Chen S, Roy K, Price BD. The FATC domains of PIKK proteins are functionally equivalent and participate in the Tip60-dependent activation of DNA-PKcs and ATM. J Biol Chem 2006; 281:15741-15746.
7. Uziel T, Lerenthal Y, Moyal L et al. Requirement of the MRN complex for ATM activation by DNA damage. EMBO J 2003; 22:5612-5621.
8. Huyen Y, Zgheib O, Ditullio RA, Jr. et al. Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks. Nature 2004; 432:406-411.
9. Goodarzi AA, Noon AT, Deckbar D et al. ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin. Mol Cell 2008; 31:167-177.
10. Goodarzi AA, Noon AT, Jeggo PA. The impact of heterochromatin on DSB repair. Biochem Soc Trans 2009; 37 (Pt 3):569-576.