Radiation Dose-Volume Effects in the Larynx and Pharynx

International Journal of Radiation Oncology Biology Physics

Volumn 76, Issue 3 SUPPL., 2010, Pages

  Rancati, Tiziana ^a   Schwarz, Marco ^b   Allen, Aaron M ^c   Feng, Felix ^d   Popovtzer, Aron ^c   Mittal, Bharat ^e   Eisbruch, Avraham ^d  

^a NATIONAL CANCER INSTITUTE   (Italy)

^b ATreP Agenzia Provinciale Per la Protonterapia   (Italy)

^c RABIN MEDICAL CENTER   (Israel)

^d UNIVERSITY OF MICHIGAN   (United States)

^e NORTHWESTERN UNIVERSITY   (United States)

Author keywords

dose effect; dysphagia; Larynx; pharynx; radiotherapy

Indexed keywords

ANATOMICAL STRUCTURES; DOSE EFFECT; DOSE EFFECTS; DOSE-VOLUME; RADIATION DOSE;

RADIATION EFFECTS;

RADIOTHERAPY;

ANTINEOPLASTIC AGENT;

ADVANCED CANCER; ARTICLE; ASPIRATION; BIOLOGICAL MODEL; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; DISEASE SEVERITY; DYSPHAGIA; HUMAN; LARYNX CANCER; LARYNX DISORDER; LARYNX EDEMA; MATHEMATICAL MODEL; MOUTH CAVITY; ORGAN SIZE; PRIORITY JOURNAL; QUALITY OF LIFE; RADIATION DOSE; RADIATION HAZARD; RADIATION INJURY; SCORING SYSTEM;

DEGLUTITION DISORDERS; HUMANS; LARYNGEAL EDEMA; LARYNX; PHARYNX; RADIATION INJURIES; RADIOTHERAPY; RADIOTHERAPY DOSAGE;

EID: 76449085827     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2009.03.079     Document Type: Article

References (25)

1. Fung K., Yoo J., Leeper H.A., et al. Effects of head and neck radiation therapy on vocal function. J Otolaryngol 30 (2001) 133-139
2. Forastiere A.A., Goepfert H., Maor M., et al. Concurrent chemotherapy and radiotherapy for organ preservation in advanced laryngeal cancer. N Engl J Med 349 (2003) 2091-2098
3. Eisbruch A., Lyden T., Bradford C.R., et al. Objective assessment of swallowing dysfunction and aspiration after radiation concurrent with chemotherapy for head and neck cancer. Int J Radiat Oncol Biol Phys 53 (2002) 23-28
4. Hirano M. Clinical examination of voice. In: Arnold G.E., Winkel F., and Wyke B.D. (Eds). Disorders of human communication (1981), Springer-Verlag, New York 81-84
5. Fung K., Yoo J., Leeper A., et al. Vocal function following radiation for non-laryngeal versus laryngeal tumors of the head and neck. Laryngoscope 111 (2001) 1920-1924
6. Hocevar-Boltezar I., Zargi M., and Strojan P. Risk factors for voice quality after radiotherapy for early glottic cancer. Radiother Oncol 93 (2009) 524-529
7. Dornfeld K., Simmons J.R., Karnell L., et al. Radiation doses to structures within and adjacent to the larynx are correlated with long-term diet and speech-related quality of life. Int J Radiat Oncol Biol Phys 68 (2007) 750-757
8. Sanguineti G., Adapala P., Endres E.J., et al. Dosimetric predictors of laryngeal edema. Int J Radiat Oncol Biol Phys 68 (2007) 741-749
9. Fu K.K., Woofhouse R.J., Quivey J.M., et al. The significance of laryngeal edema following radiotherapy of carcinoma of the vocal cord. Cancer 49 (1982) 6555-6558
10. Rancati T., Sanguineti G., and Fiorino C. NTCP modeling of subacute/late laryngeal edema scored by fiberoptic examination: evidence of a large volume effect. Int J Radiat Oncol Biol Phys 69 Suppl. 3 (2007) S409-S410
11. Kendall K.A., McKenzie S.W., Leonard R.J., et al. Timing of events in normal swallowing: A videofluroscopic study. Dysphagia 15 (2000) 74-84
12. Logemann J. Mechanism of normal and abnormal swallowing. In: Cummings J.W., Flint P.W., Haughey B.A., et al. (Eds). Otolaryngology: head and neck surgery. 5th ed (2008), St. Louis: Mosby
13. Eisbruch A., Schwartz M., Rasch C., et al. Dysphagia and aspiration after chemoradiotherapy for head and neck cancer: Which anatomic structures are affected and can they be spared by IMRT?. Int J Radiat Oncol Biol Phys 60 (2004) 1425-1439
14. Feng F.Y., Kim H.M., Lyden T.H., et al. Intensity-modulated radiotherapy of head and neck cancer aiming to reduce dysphagia: Early dose-effect relationships for the swallowing structures. Int J Radiat Oncol Biol Phys 68 (2007) 1289-1298
15. Levandag P.C., Teguh D.N., Voet P., et al. Dysphagia disorders in patients with cancer of the oropharynx are significantly affected by the radiation therapy dose to the superior and middle constrictor muscle: A dose-effect relationship. Radiother Oncol 85 (2007) 64-73
16. Jensen K., Lambertsen K., and Grau C. Late swallowing dysfunction and dysphagia after radiotherapy for pharynx cancer: Frequency, intensity, and correlation with dose and volume parameters. Radiother Oncol 85 (2007) 74-82
17. Fua T.F., Corry J., Milner A.D., et al. Intensity-modulated radiotherapy for nasopharyngeal carcinoma: Clinical correlation of dose to the pharyngoesophageal axis and dysphagia. Int J Radiat Oncol Biol Phys 67 (2007) 976-981
18. Doornaert P., Slotman B.J., Rietveld D.H.F., et al. The mean radiation dose in pharyngeal structures is a strong predictor of acute and persistent swallowing dysfunction and quality of life in head and neck radiotherapy. [Abstract]. Int J Radiat Oncol Biol Phys 69 Suppl (2007) 55
19. Caglar H.B., Allen A.M., Othus M., et al. Dose to the larynx predicts for swallowing complications following IMRT and chemotherapy. Int J Radiat Oncol Biol Phys 72 (2008) 1110-1118
20. O'Meara E.A., Machtay M., Moughan J., et al. Association between radiation doses to pharyngeal regions and severe late toxicity in head and neck cancer patients treated with concurrent chemoradiotherapy-An RTOG analysis. [Abstract]. Int J Radiat Oncol Biol Phys 69 Suppl (2007) 54
21. Laurell G., Kraepelien T., Mavroidis P., et al. Stricture of the proximal esophagus in head and neck carcinoma patients after radiotherapy. Cancer 97 (2003) 1693-1700
22. Rosenthal D.I., Lewin J.S., and Eisbruch A. Prevention and treatment of dysphagia and aspiration after chemoradiation for head and neck cancer. J Clin Oncol 24 (2006) 2636-2643
23. Mekhail T.M., Adelstein D.J., Rybicki L.A., et al. Enteral nutrition during the treatment of head and neck carcinoma: Is percutaneous endoscopic gastrostomy tube preferable to a nasogastric tube?. Cancer 91 (2001) 1785-1790
24. Brizel D.M., Wasserman T.H., Henke M., et al. Phase 3 randomized trial of amifostine as a radioprotector in head and neck cancer. J Clin Oncol 18 (2000) 3339-3345
25. Langerman A., MacCracken E., Kasza K., et al. Aspiration in chemoradiated patients with head and neck cancer. Arch Otolaryngol Head Neck Surg 133 (2007) 1289-1295