Comparison of enzymatic properties of DNA-abzymes and human DNAses

Nucleosides, Nucleotides and Nucleic Acids

Volumn 23, Issue 6-7, 2004, Pages 1053-1056

  Baranovskii, A G ^a   Odintsova, E S ^b   Buneva, V N ^a,b   Doronin, B M ^c   Nevinsky, G A ^a,b  

^a INSTITUTE OF CHEMICAL BIOLOGY AND FUNDAMENTAL MEDICINE   (Russian Federation)

^b NOVOSIBIRSK STATE UNIVERSITY   (Russian Federation)

^c NOVOSIBIRSK STATE MEDICAL UNIVERSITY   (Russian Federation)

Author keywords

Catalytic IgG; DNase activity; Multiple sclerosis; Substrate specificity

Indexed keywords

ANTIBODY; DEOXYRIBONUCLEASE; DNA ABZYME; DOUBLE STRANDED DNA; METAL ION; POLYCLONAL ANTIBODY; SINGLE STRANDED DNA; UNCLASSIFIED DRUG;

AUTOIMMUNE DISEASE; CONFERENCE PAPER; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SPECIFICITY; HUMAN; HYDROLYSIS; MULTIPLE SCLEROSIS; SYSTEMIC LUPUS ERYTHEMATOSUS;

ANTIBODIES, CATALYTIC; BASE SEQUENCE; DEOXYRIBONUCLEASES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; HYDROLYSIS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MULTIPLE SCLEROSIS; SUBSTRATE SPECIFICITY;

EID: 7644242452     PISSN: 15257770     EISSN: None     Source Type: Journal    
DOI: 10.1081/NCN-200026068     Document Type: Conference Paper

References (3)

1. Nevinsky, G.A.; Favorova, O.O.; Buneva, B.N. Catalytic antibodies: new characters in the protein repertoire. In Protein-Protein Interactions; Golemis, E., Ed.; Cold Spring Harbor Lab. Press: New York, 2002; 523-534.
2. Boiko, A.N.; Favorova, O.O. Multiple sclerosis: molecular and cellular mechanisms. Mol. Biol. (Mosk.) 1995, 29 (4), 727-749.
3. Baranovskii, A.G.; Kanyshkova, T.G.; Mogelnitskii, A.S.; Naumov, V.A.; Buneva, V.N.; Gusev, E.I.; Boiko, A.N.; Zargarova, T.A.; Favorova, O.O.; Nevinsky, G.A. Polyclonal antibodies from blood and cerebrospinal fluid of patients with multiple sclerosis effectively hydrolyze DNA and RNA. Biochemistry (Mosc.) 1998, 63 (11), 1239-1248.