메뉴 건너뛰기




Volumn 78, Issue 22, 2004, Pages 12519-12528

Granzymes and caspase 3 play important roles in control of gammaherpesvirus latency

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; GRANZYME A; GRANZYME B; PERFORIN;

EID: 7644240321     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.78.22.12519-12528.2004     Document Type: Article
Times cited : (27)

References (83)
  • 1
    • 0034954419 scopus 로고    scopus 로고
    • Adenovirus L4-100K assembly protein is a granzyme B substrate that potently inhibits granzyme B-mediated cell death
    • Andrade, F., H. G. Bull, N. A. Thornberry, G. W. Ketner, L. A. Casciola-Rosen, and A. Rosen. 2001. Adenovirus L4-100K assembly protein is a granzyme B substrate that potently inhibits granzyme B-mediated cell death. Immunity 14:751-761.
    • (2001) Immunity , vol.14 , pp. 751-761
    • Andrade, F.1    Bull, H.G.2    Thornberry, N.A.3    Ketner, G.W.4    Casciola-Rosen, L.A.5    Rosen, A.6
  • 2
    • 0031091770 scopus 로고    scopus 로고
    • Inhibition of CPP32-like proteases prevents granzyme B- and Fas-, but not granzyme A-based cytotoxicity exerted by CTL clones
    • Anel, A., S. Gamen, M. A. Alava, A. M. Schmitt-Verhulst, A. Pineiro, and J. Naval. 1997. Inhibition of CPP32-like proteases prevents granzyme B- and Fas-, but not granzyme A-based cytotoxicity exerted by CTL clones. J. Immunol. 158:1999-2006.
    • (1997) J. Immunol. , vol.158 , pp. 1999-2006
    • Anel, A.1    Gamen, S.2    Alava, M.A.3    Schmitt-Verhulst, A.M.4    Pineiro, A.5    Naval, J.6
  • 3
    • 0029039291 scopus 로고
    • Loss of cytotoxic T lymphocyte function in Chediak-Higashi syndrome arises from a secretory defect that prevents lytic granule exocytosis
    • Baetz, K., S. Isaaz, and G. M. Griffiths. 1995. Loss of cytotoxic T lymphocyte function in Chediak-Higashi syndrome arises from a secretory defect that prevents lytic granule exocytosis. J. Immunol. 154:6122-6131.
    • (1995) J. Immunol. , vol.154 , pp. 6122-6131
    • Baetz, K.1    Isaaz, S.2    Griffiths, G.M.3
  • 4
    • 0034026759 scopus 로고    scopus 로고
    • Antiapoptotic herpesvirus bcl-2 homologs escape caspase-mediated conversion to proapoptotic proteins
    • Bellows, D. S., B. N. Chau, P. Lee, Y. Lazebnik, W. H. Burns, and J. M. Hardwick. 2000. Antiapoptotic herpesvirus bcl-2 homologs escape caspase-mediated conversion to proapoptotic proteins. J. Virol. 74:5024-5031.
    • (2000) J. Virol. , vol.74 , pp. 5024-5031
    • Bellows, D.S.1    Chau, B.N.2    Lee, P.3    Lazebnik, Y.4    Burns, W.H.5    Hardwick, J.M.6
  • 5
    • 0033137079 scopus 로고    scopus 로고
    • Granzyme A loading induces rapid cytolysis and a novel form of DNA damage independently of caspase activation
    • Beresford, P. J., Z. Xia, A. H. Greenberg, and J. Lieberman. 1999. Granzyme A loading induces rapid cytolysis and a novel form of DNA damage independently of caspase activation. Immunity 10:585-594.
    • (1999) Immunity , vol.10 , pp. 585-594
    • Beresford, P.J.1    Xia, Z.2    Greenberg, A.H.3    Lieberman, J.4
  • 7
    • 0019266011 scopus 로고
    • Isolation of five strains of herpesviruses from two species of free living small rodents
    • Blaskovic, D., M. Stancekova, J. Svobodova, and J. Mistrikova. 1980. Isolation of five strains of herpesviruses from two species of free living small rodents. Acta Virol. 24:468.
    • (1980) Acta Virol. , vol.24 , pp. 468
    • Blaskovic, D.1    Stancekova, M.2    Svobodova, J.3    Mistrikova, J.4
  • 8
    • 0021252881 scopus 로고
    • Experimental pathogenesis of murine herpesvirus in newborn mice
    • Blaskovic, D., D. Stanekova, and J. Rajcani. 1984. Experimental pathogenesis of murine herpesvirus in newborn mice. Acta Virol. 28:225-231.
    • (1984) Acta Virol. , vol.28 , pp. 225-231
    • Blaskovic, D.1    Stanekova, D.2    Rajcani, J.3
  • 10
    • 0033948614 scopus 로고    scopus 로고
    • Disruption of the murine gammaherpesvirus 68 M1 open reading frame leads to enhanced reactivation from latency
    • Clambey, E. T., H. W. Virgin, and S. H. Speck. 2000. Disruption of the murine gammaherpesvirus 68 M1 open reading frame leads to enhanced reactivation from latency. J. Virol. 74:1973-1984.
    • (2000) J. Virol. , vol.74 , pp. 1973-1984
    • Clambey, E.T.1    Virgin, H.W.2    Speck, S.H.3
  • 11
    • 0036281954 scopus 로고    scopus 로고
    • Characterization of a spontaneous 9.5-kilobase-deletion mutant of murine gammaherpesvirus 68 reveals tissue-specific genetic requirements for latency
    • Clambey, E. T., H. W. Virgin, and S. H. Speck. 2002. Characterization of a spontaneous 9.5-kilobase-deletion mutant of murine gammaherpesvirus 68 reveals tissue-specific genetic requirements for latency. J. Virol. 76:6532-6544.
    • (2002) J. Virol. , vol.76 , pp. 6532-6544
    • Clambey, E.T.1    Virgin, H.W.2    Speck, S.H.3
  • 12
    • 0029099845 scopus 로고
    • Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B
    • Darmon, A. J., D. W. Nicholson, and R. C. Bleackley. 1995. Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B. Nature 377:446-448.
    • (1995) Nature , vol.377 , pp. 446-448
    • Darmon, A.J.1    Nicholson, D.W.2    Bleackley, R.C.3
  • 13
    • 0033769857 scopus 로고    scopus 로고
    • Dependence of granzyme B-mediated cell death on a pathway regulated by Bcl-2 or its viral homolog, BHRF1
    • Davis, J. E., V. R. Sutton, M. J. Smyth, and J. A. Trapani. 2000. Dependence of granzyme B-mediated cell death on a pathway regulated by Bcl-2 or its viral homolog, BHRF1. Cell Death Differ. 7:973-983.
    • (2000) Cell Death Differ. , vol.7 , pp. 973-983
    • Davis, J.E.1    Sutton, V.R.2    Smyth, M.J.3    Trapani, J.A.4
  • 14
    • 0035479955 scopus 로고    scopus 로고
    • The role of cytotoxicity in lymphocyte homeostasis
    • de Saint, B. G., and A. Fischer. 2001. The role of cytotoxicity in lymphocyte homeostasis. Curr. Opin. Immunol. 13:549-554.
    • (2001) Curr. Opin. Immunol. , vol.13 , pp. 549-554
    • De Saint, B.G.1    Fischer, A.2
  • 15
    • 0037333391 scopus 로고    scopus 로고
    • Loss of the perform cytotoxic pathway predisposes mice to experimental cytomegalovirus retinitis
    • Dix, R. D., E. R. Podack, and S. W. Cousins. 2003. Loss of the perform cytotoxic pathway predisposes mice to experimental cytomegalovirus retinitis. J. Virol. 77:3402-3408.
    • (2003) J. Virol. , vol.77 , pp. 3402-3408
    • Dix, R.D.1    Podack, E.R.2    Cousins, S.W.3
  • 16
    • 0025979857 scopus 로고
    • In vivo primed mouse T cells selectively express T cell-specific serine proteinase-1 and the proteinase-like molecules granzyme B and C
    • Ebnet, K., J. Chluba-de Tapia, U. Hurtenbach, M. D. Kramer, and M. M. Simon. 1991. In vivo primed mouse T cells selectively express T cell-specific serine proteinase-1 and the proteinase-like molecules granzyme B and C. Int. Immunol. 3:9-19.
    • (1991) Int. Immunol. , vol.3 , pp. 9-19
    • Ebnet, K.1    Chluba-de Tapia, J.2    Hurtenbach, U.3    Kramer, M.D.4    Simon, M.M.5
  • 18
    • 0025313893 scopus 로고
    • Murine herpesvirus 68 is genetically related to the gammaherpesviruses Epstein-Barr virus and herpesvirus saimiri
    • Efstathiou, S., Y. M. Ho, S. Hall, C. J. Styles, S. D. Scott, and U. A. Gompels. 1990. Murine herpesvirus 68 is genetically related to the gammaherpesviruses Epstein-Barr virus and herpesvirus saimiri. J. Gen. Virol. 71:1365-1372.
    • (1990) J. Gen. Virol. , vol.71 , pp. 1365-1372
    • Efstathiou, S.1    Ho, Y.M.2    Hall, S.3    Styles, C.J.4    Scott, S.D.5    Gompels, U.A.6
  • 19
    • 0027179405 scopus 로고
    • Pathogenesis of murine gammaherpesvirus infection in mice deficient in CD4 and CD8 T cells
    • Ehtisham, S., N. P. Sunil-Chandra, and A. A. Nash. 1993. Pathogenesis of murine gammaherpesvirus infection in mice deficient in CD4 and CD8 T cells. J. Virol. 67:5247-5252.
    • (1993) J. Virol. , vol.67 , pp. 5247-5252
    • Ehtisham, S.1    Sunil-Chandra, N.P.2    Nash, A.A.3
  • 20
    • 0034662270 scopus 로고    scopus 로고
    • Latent murine gamma-herpesvirus infection is established in activated B cells, dendritic cells, and macrophages
    • Flano, E., S. M. Husain, J. T. Sample, D. L. Woodland, and M. A. Blackman. 2000. Latent murine gamma-herpesvirus infection is established in activated B cells, dendritic cells, and macrophages. J. Immunol. 165:1074-1081.
    • (2000) J. Immunol. , vol.165 , pp. 1074-1081
    • Flano, E.1    Husain, S.M.2    Sample, J.T.3    Woodland, D.L.4    Blackman, M.A.5
  • 23
    • 0032726606 scopus 로고    scopus 로고
    • Perform pathway is essential for protection of mice against lethal ocular HSV-1 challenge but not corneal scarring
    • Ghiasi, H., S. Cai, G. Perng, A. B. Nesburn, and S. L. Wechsler. 1999. Perform pathway is essential for protection of mice against lethal ocular HSV-1 challenge but not corneal scarring. Virus Res. 65:97-101.
    • (1999) Virus Res. , vol.65 , pp. 97-101
    • Ghiasi, H.1    Cai, S.2    Perng, G.3    Nesburn, A.B.4    Wechsler, S.L.5
  • 24
    • 0032544268 scopus 로고    scopus 로고
    • Apoptotic pathways: The roads to ruin
    • Green, D. R. 1998. Apoptotic pathways: the roads to ruin. Cell 94:695-698.
    • (1998) Cell , vol.94 , pp. 695-698
    • Green, D.R.1
  • 26
    • 0028258577 scopus 로고
    • Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells
    • Heusel, J. W., R. L. Wesselschmidt, S. Shresta, J. H. Russel, and T. J. Ley. 1994. Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells. Cell 76:977-987.
    • (1994) Cell , vol.76 , pp. 977-987
    • Heusel, J.W.1    Wesselschmidt, R.L.2    Shresta, S.3    Russel, J.H.4    Ley, T.J.5
  • 27
    • 0036146179 scopus 로고    scopus 로고
    • Disruption of the M2 gene of murine gammaherpesvirus 68 alters splenic latency following intranasal, but not intraperitoneal, inoculation
    • Jacoby, M. A., H. W. Virgin, I. V., and S. H. Speck. 2002. Disruption of the M2 gene of murine gammaherpesvirus 68 alters splenic latency following intranasal, but not intraperitoneal, inoculation. J. Virol. 76:1790-1801.
    • (2002) J. Virol. , vol.76 , pp. 1790-1801
    • Jacoby, M.A.1    Virgin, H.W.2    V., I.3    Speck, S.H.4
  • 32
    • 0036669274 scopus 로고    scopus 로고
    • Critical role of complement and viral evasion of complement in acute, persistent, and latent gamma-herpesvirus infection
    • Kapadia, S. B., B. Levine, S. H. Speck, and H. W. Virgin. 2002. Critical role of complement and viral evasion of complement in acute, persistent, and latent gamma-herpesvirus infection. Immunity 17:143-155.
    • (2002) Immunity , vol.17 , pp. 143-155
    • Kapadia, S.B.1    Levine, B.2    Speck, S.H.3    Virgin, H.W.4
  • 33
    • 0842264040 scopus 로고    scopus 로고
    • Chronic active Epstein-Barr virus infection associated with mutations in perform that impair its maturation
    • Katano, H., M. A. Ali, A. C. Patera, M. Catalfamo, E. S. Jatte, H. Kimura, J. K. Dale, S. E. Straus, and J. I. Cohen. 2004. Chronic active Epstein-Barr virus infection associated with mutations in perform that impair its maturation. Blood 103:1244-1252.
    • (2004) Blood , vol.103 , pp. 1244-1252
    • Katano, H.1    Ali, M.A.2    Patera, A.C.3    Catalfamo, M.4    Jatte, E.S.5    Kimura, H.6    Dale, J.K.7    Straus, S.E.8    Cohen, J.I.9
  • 36
    • 0000942112 scopus 로고    scopus 로고
    • Epstein-Barr virus and its replication
    • D. M. Knipe and P. Howley (ed.), Lippincott Williams & Wilkins, Philadelphia, Pa.
    • Kieff, E., and A. B. Rickinson. 2001. Epstein-Barr virus and its replication, p. 2511-2573. In D. M. Knipe and P. Howley (ed.), Fields virology. Lippincott Williams & Wilkins, Philadelphia, Pa.
    • (2001) Fields Virology , pp. 2511-2573
    • Kieff, E.1    Rickinson, A.B.2
  • 37
    • 0032751735 scopus 로고    scopus 로고
    • T-cell vaccination alters the course of murine herpesvirus 68 infection and the establishment of viral latency in mice
    • Liu, L., E. J. Usherwood, M. A. Blackman, and D. L. Woodland. 1999. T-cell vaccination alters the course of murine herpesvirus 68 infection and the establishment of viral latency in mice. J. Virol. 73:9849-9857.
    • (1999) J. Virol. , vol.73 , pp. 9849-9857
    • Liu, L.1    Usherwood, E.J.2    Blackman, M.A.3    Woodland, D.L.4
  • 38
    • 0038806366 scopus 로고    scopus 로고
    • Selective gene expression of latent murine gammaherpesvirus 68 in B lymphocytes
    • Marques, S., S. Efstathiou, K. G. Smith, M. Haury, and J. P. Simas. 2003. Selective gene expression of latent murine gammaherpesvirus 68 in B lymphocytes. J. Virol. 77:7308-7318.
    • (2003) J. Virol. , vol.77 , pp. 7308-7318
    • Marques, S.1    Efstathiou, S.2    Smith, K.G.3    Haury, M.4    Simas, J.P.5
  • 39
    • 9344261615 scopus 로고    scopus 로고
    • The cytotoxic cell protease granzyme B initiates apoptosis in a cell-free system by proteolytic processing and activation of the ICE/CED-3 family protease, CPP32, via a novel two-step mechanism
    • Martin, S. J., G. P. Amarante-Mendes, L. Shi, T. H. Chuang, C. A. Casiano, G. A. O'Brien, P. Fitzgerald, E. M. Tan, G. M. Bokoch, A. H. Greenberg, and D. R. Green. 1996. The cytotoxic cell protease granzyme B initiates apoptosis in a cell-free system by proteolytic processing and activation of the ICE/CED-3 family protease, CPP32, via a novel two-step mechanism. EMBO J. 15:2407-2416.
    • (1996) EMBO J. , vol.15 , pp. 2407-2416
    • Martin, S.J.1    Amarante-Mendes, G.P.2    Shi, L.3    Chuang, T.H.4    Casiano, C.A.5    O'Brien, G.A.6    Fitzgerald, P.7    Tan, E.M.8    Bokoch, G.M.9    Greenberg, A.H.10    Green, D.R.11
  • 43
    • 0242608521 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus immunoevasion and tumorigenesis: Two sides of the same coin?
    • Moore, P. S., and Y. Chang. 2003. Kaposi's sarcoma-associated herpesvirus immunoevasion and tumorigenesis: two sides of the same coin? Annu. Rev. Microbiol. 57:609-639.
    • (2003) Annu. Rev. Microbiol. , vol.57 , pp. 609-639
    • Moore, P.S.1    Chang, Y.2
  • 44
    • 0030014911 scopus 로고    scopus 로고
    • Granzyme A is critical for recovery of mice from infection with the natural cytopathic viral pathogen, ectromelia
    • Mullbacher, A., K. Ebnet, R. V. Blanden, R. T. Hla, T. Stehle, C. Museteanu, and M. M. Simon. 1996. Granzyme A is critical for recovery of mice from infection with the natural cytopathic viral pathogen, ectromelia. Proc. Natl. Acad. Sci. USA 93:5783-5787.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 5783-5787
    • Mullbacher, A.1    Ebnet, K.2    Blanden, R.V.3    Hla, R.T.4    Stehle, T.5    Museteanu, C.6    Simon, M.M.7
  • 45
    • 0344097497 scopus 로고    scopus 로고
    • Perform is essential for control of ectromelia virus but not related poxviruses in mice
    • Mullbacher, A., R. T. Hla, C. Museteanu, and M. M. Simon. 1999. Perform is essential for control of ectromelia virus but not related poxviruses in mice. J. Virol. 73:1665-1667.
    • (1999) J. Virol. , vol.73 , pp. 1665-1667
    • Mullbacher, A.1    Hla, R.T.2    Museteanu, C.3    Simon, M.M.4
  • 46
    • 0033598718 scopus 로고    scopus 로고
    • Granzymes are the essential downstream effector molecules for the control of primary virus infections by cytolytic leukocytes
    • Mullbacher, A., P. Waring, H. R. Tha, T. Tran, S. Chin, T. Stehle, C. Museteanu, and M. M. Simon. 1999. Granzymes are the essential downstream effector molecules for the control of primary virus infections by cytolytic leukocytes. Proc. Natl. Acad. Sci. USA 96:13950-13955.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 13950-13955
    • Mullbacher, A.1    Waring, P.2    Tha, H.R.3    Tran, T.4    Chin, S.5    Stehle, T.6    Museteanu, C.7    Simon, M.M.8
  • 47
    • 0036312429 scopus 로고    scopus 로고
    • The differential contribution of granzyme A and granzyme B in cytotoxic T lymphocyte-mediated apoptosis is determined by the quality of target cells
    • Pardo, J., S. Balkow, A. Anel, and M. M. Simon. 2002. The differential contribution of granzyme A and granzyme B in cytotoxic T lymphocyte-mediated apoptosis is determined by the quality of target cells, Eur. J. Immunol. 32:1980-1985.
    • (2002) Eur. J. Immunol. , vol.32 , pp. 1980-1985
    • Pardo, J.1    Balkow, S.2    Anel, A.3    Simon, M.M.4
  • 48
    • 0033986159 scopus 로고    scopus 로고
    • + cell granules, restricts the spread of herpes simplex virus in the peripheral nervous systems of experimentally infected mice
    • + cell granules, restricts the spread of herpes simplex virus in the peripheral nervous systems of experimentally infected mice. J. Virol. 74:1029-1032.
    • (2000) J. Virol. , vol.74 , pp. 1029-1032
    • Pereira, R.A.1    Simon, M.M.2    Simmons, A.3
  • 50
    • 0026657768 scopus 로고
    • Quantitative polymerase chain reaction analysis of cytotoxic cell proteinase gene transcripts in T cells. Pattern of expression is dependent on the nature of the stimulus
    • Prendergast, J. A., C. D. Helgason, and R. C. Bleackley. 1992. Quantitative polymerase chain reaction analysis of cytotoxic cell proteinase gene transcripts in T cells. Pattern of expression is dependent on the nature of the stimulus. J. Biol. Chem. 267:5090-5095.
    • (1992) J. Biol. Chem. , vol.267 , pp. 5090-5095
    • Prendergast, J.A.1    Helgason, C.D.2    Bleackley, R.C.3
  • 51
    • 0028955325 scopus 로고
    • Granzyme B is inhibited by the cowpox virus serpin cytokine response modifier A
    • Quan, L. T., A. Caputo, R. C. Bleackley, D. J. Pickup, and G. S. Salvesen. 1995. Granzyme B is inhibited by the cowpox virus serpin cytokine response modifier A. J. Biol. Chem. 270:10377-10379.
    • (1995) J. Biol. Chem. , vol.270 , pp. 10377-10379
    • Quan, L.T.1    Caputo, A.2    Bleackley, R.C.3    Pickup, D.J.4    Salvesen, G.S.5
  • 54
    • 0000942113 scopus 로고    scopus 로고
    • Epstein-Barr virus
    • D. M. Knipe and P. Howley (ed.), Lippincott Williams & Wilkins, Philadelphia, Pa.
    • Rickinson, A. B. and E. Kieff. 2001. Epstein-Barr virus, p. 2575-2627. In D. M. Knipe and P. Howley (ed.), Fields virology. Lippincott Williams & Wilkins, Philadelphia, Pa.
    • (2001) Fields Virology , pp. 2575-2627
    • Rickinson, A.B.1    Kieff, E.2
  • 55
    • 0034033438 scopus 로고    scopus 로고
    • Murine cytomegalovirus replication in salivary glands is controlled by both perforin and granzymes during acute infection
    • Riera, L., M. Gariglio, G. Valente, A. Mullbacher, C. Museteanu, S. Landolfo, and M. M. Simon. 2000. Murine cytomegalovirus replication in salivary glands is controlled by both perforin and granzymes during acute infection. Eur. J. Immunol. 30:1350-1355.
    • (2000) Eur. J. Immunol. , vol.30 , pp. 1350-1355
    • Riera, L.1    Gariglio, M.2    Valente, G.3    Mullbacher, A.4    Museteanu, C.5    Landolfo, S.6    Simon, M.M.7
  • 56
    • 0034517673 scopus 로고    scopus 로고
    • Murine gammaherpesvirus M11 gene product inhibits apoptosis and is expressed during virus persistence
    • Roy, D. J., B. C. Ebrahimi, B. M. Dutia, A. A. Nash, and J. P. Stewart. 2000. Murine gammaherpesvirus M11 gene product inhibits apoptosis and is expressed during virus persistence. Arch. Virol. 145:2411-2420.
    • (2000) Arch. Virol. , vol.145 , pp. 2411-2420
    • Roy, D.J.1    Ebrahimi, B.C.2    Dutia, B.M.3    Nash, A.A.4    Stewart, J.P.5
  • 57
    • 0036217977 scopus 로고    scopus 로고
    • Lymphocyte-mediated cytotoxicity
    • Russell, J. H., and T. J. Ley. 2002. Lymphocyte-mediated cytotoxicity. Annu. Rev. Immunol. 20:323-370.
    • (2002) Annu. Rev. Immunol. , vol.20 , pp. 323-370
    • Russell, J.H.1    Ley, T.J.2
  • 58
    • 0025868622 scopus 로고
    • Cytotoxic T lymphocytes induce different types of DNA damage in target cells of different origins
    • Sellins, K. S., and J. J. Cohen. 1991. Cytotoxic T lymphocytes induce different types of DNA damage in target cells of different origins. J. Immunol. 147:795-803.
    • (1991) J. Immunol. , vol.147 , pp. 795-803
    • Sellins, K.S.1    Cohen, J.J.2
  • 60
    • 0030892138 scopus 로고    scopus 로고
    • Granzyme B (GraB) autonomously crosses the cell membrane and perforin initiates apoptosis and GraB nuclear localization
    • Shi, L., S. Mai, S. Israels, K. Browne, J. A. Trapani, and A. H. Greenberg. 1997. Granzyme B (GraB) autonomously crosses the cell membrane and perforin initiates apoptosis and GraB nuclear localization. J. Exp. Med. 185:855-866.
    • (1997) J. Exp. Med. , vol.185 , pp. 855-866
    • Shi, L.1    Mai, S.2    Israels, S.3    Browne, K.4    Trapani, J.A.5    Greenberg, A.H.6
  • 61
    • 0030802988 scopus 로고    scopus 로고
    • Residual cytotoxicity and granzyme K expression in granzyme A-deficient cytotoxic lymphocytes
    • Shresta, S., P. Goda, R. Wesselschmidt, and T. J. Ley. 1997. Residual cytotoxicity and granzyme K expression in granzyme A-deficient cytotoxic lymphocytes. J. Biol. Chem. 272:20236-20244.
    • (1997) J. Biol. Chem. , vol.272 , pp. 20236-20244
    • Shresta, S.1    Goda, P.2    Wesselschmidt, R.3    Ley, T.J.4
  • 62
    • 0033136315 scopus 로고    scopus 로고
    • Granzyme A initiates an alternative pathway for granule-mediated apoptosis
    • Shresta, S., T. A. Graubert, D. A. Thomas, S. Z. Raptis, and T. J. Ley. 1999. Granzyme A initiates an alternative pathway for granule-mediated apoptosis. Immunity 10:595-605.
    • (1999) Immunity , vol.10 , pp. 595-605
    • Shresta, S.1    Graubert, T.A.2    Thomas, D.A.3    Raptis, S.Z.4    Ley, T.J.5
  • 63
    • 0029055757 scopus 로고
    • Natural killer and lymphokine-activated killer cells require granzyme B for the rapid induction of apoptosis in susceptible target cells
    • Shresta, S., D. M. Macivor, J. W. Heusel, J. H. Russell, and T. J. Ley. 1995. Natural killer and lymphokine-activated killer cells require granzyme B for the rapid induction of apoptosis in susceptible target cells. Proc. Natl. Acad. Sci. USA 92:5679-5683.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5679-5683
    • Shresta, S.1    Macivor, D.M.2    Heusel, J.W.3    Russell, J.H.4    Ley, T.J.5
  • 64
    • 0030723209 scopus 로고    scopus 로고
    • In vitro- and ex vivo-derived cytolytic leukocytes from granzyme A x B double knockout mice are defective in granule-mediated apoptosis but not lysis of target cells
    • Simon, M. M., M. Hausmann, T. Tran, K. Ebnet, J. Tschopp, R. ThaHla, and A. Mullbacher. 1997. In vitro- and ex vivo-derived cytolytic leukocytes from granzyme A x B double knockout mice are defective in granule-mediated apoptosis but not lysis of target cells. J. Exp. Med. 186:1781-1786.
    • (1997) J. Exp. Med. , vol.186 , pp. 1781-1786
    • Simon, M.M.1    Hausmann, M.2    Tran, T.3    Ebnet, K.4    Tschopp, J.5    Thahla, R.6    Mullbacher, A.7
  • 69
    • 0026693757 scopus 로고
    • Virological and pathological features of mice infected with murine gammaherpesvirus 68
    • Sunil-Chandra, N. P., S. Efstathiou, J. Arno, and A. A. Nash. 1992. Virological and pathological features of mice infected with murine gammaherpesvirus 68. J. Gen. Virol. 73:2347-2356.
    • (1992) J. Gen. Virol. , vol.73 , pp. 2347-2356
    • Sunil-Chandra, N.P.1    Efstathiou, S.2    Arno, J.3    Nash, A.A.4
  • 70
    • 0027043122 scopus 로고
    • Murine gammaherpesvirus 68 establishes a latent infection in mouse B lymphocytes in vivo
    • Sunil-Chandra, N. P., S. Efstathiou, and A. A. Nash. 1992. Murine gammaherpesvirus 68 establishes a latent infection in mouse B lymphocytes in vivo. J. Gen. Virol. 73:3275-3279.
    • (1992) J. Gen. Virol. , vol.73 , pp. 3275-3279
    • Sunil-Chandra, N.P.1    Efstathiou, S.2    Nash, A.A.3
  • 71
    • 0033673428 scopus 로고    scopus 로고
    • DFF45/ICAD can be directly processed by granzyme B during the induction of apoptosis
    • Thomas, D. A., C. Du, M. Xu, X. Wang, and T. J. Ley. 2000. DFF45/ICAD can be directly processed by granzyme B during the induction of apoptosis. Immunity 12:621-632.
    • (2000) Immunity , vol.12 , pp. 621-632
    • Thomas, D.A.1    Du, C.2    Xu, M.3    Wang, X.4    Ley, T.J.5
  • 72
    • 0036635343 scopus 로고    scopus 로고
    • Immune control of the number and reactivation phenotype of cells latently infected with a gammaherpesvirus
    • Tibbetts, S. A., L. Van Dyk, S. H. Speck, and H. W. Virgin. 2002. Immune control of the number and reactivation phenotype of cells latently infected with a gammaherpesvirus. J. Virol. 76:7125-7132.
    • (2002) J. Virol. , vol.76 , pp. 7125-7132
    • Tibbetts, S.A.1    Van Dyk, L.2    Speck, S.H.3    Virgin, H.W.4
  • 75
    • 0033867628 scopus 로고    scopus 로고
    • The murine gammaherpesvirus 68 v-cyclin is a critical regulator of reactivation from latency
    • Van Dyk, L. F., H. W. Virgin, and S. H. Speck. 2000. The murine gammaherpesvirus 68 v-cyclin is a critical regulator of reactivation from latency. J. Virol. 74:7451-7461.
    • (2000) J. Virol. , vol.74 , pp. 7451-7461
    • Van Dyk, L.F.1    Virgin, H.W.2    Speck, S.H.3
  • 77
    • 0032978606 scopus 로고    scopus 로고
    • Three distinct regions of the murine gammaherpesvirus 68 genome are transcriptionally active in latently infected mice
    • Virgin, H. W., R. M. Presti, X.-Y. Li, C. Liu, and S. H. Speck. 1999. Three distinct regions of the murine gammaherpesvirus 68 genome are transcriptionally active in latently infected mice. J. Virol. 73:2321-2332.
    • (1999) J. Virol. , vol.73 , pp. 2321-2332
    • Virgin, H.W.1    Presti, R.M.2    Li, X.-Y.3    Liu, C.4    Speck, S.H.5
  • 79
    • 0032861298 scopus 로고    scopus 로고
    • The murine gammaherpesvirus-68 M11 protein inhibits Fas- and TNF-induced apoptosis
    • Wang, G. H., T. L. Garvey, and J. I. Cohen. 1999. The murine gammaherpesvirus-68 M11 protein inhibits Fas- and TNF-induced apoptosis. J. Gen. Virol. 80:2737-2740.
    • (1999) J. Gen. Virol. , vol.80 , pp. 2737-2740
    • Wang, G.H.1    Garvey, T.L.2    Cohen, J.I.3
  • 80
    • 0029817996 scopus 로고    scopus 로고
    • Mature B cells are required for acute splenic infection, but not for establishment of latency, by murine gammaherpesvirus 68
    • Week, K. E., M. L. Barkon, L. I. Yoo, S. H. Speck, and H. W. Virgin. 1996. Mature B cells are required for acute splenic infection, but not for establishment of latency, by murine gammaherpesvirus 68. J. Virol. 70: 6775-6780.
    • (1996) J. Virol. , vol.70 , pp. 6775-6780
    • Week, K.E.1    Barkon, M.L.2    Yoo, L.I.3    Speck, S.H.4    Virgin, H.W.5
  • 81
    • 0033061214 scopus 로고    scopus 로고
    • B cells regulate murine gammaherpesvirus 68 latency
    • Week, K. E., S. S. Kim, H. W. Virgin, and S. H. Speck. 1999. B cells regulate murine gammaherpesvirus 68 latency. J. Virol. 73:4651-4661.
    • (1999) J. Virol. , vol.73 , pp. 4651-4661
    • Week, K.E.1    Kim, S.S.2    Virgin, H.W.3    Speck, S.H.4
  • 82
    • 0032975256 scopus 로고    scopus 로고
    • Macrophages are the major reservoir of latent murine gammaherpesvirus 68 in peritoneal cells
    • Week, K. E., S. S. Kim, H. W. Virgin, and S. H. Speck. 1999. Macrophages are the major reservoir of latent murine gammaherpesvirus 68 in peritoneal cells. J. Virol. 73:3273-3283.
    • (1999) J. Virol. , vol.73 , pp. 3273-3283
    • Week, K.E.1    Kim, S.S.2    Virgin, H.W.3    Speck, S.H.4
  • 83
    • 0036177484 scopus 로고    scopus 로고
    • Epstein-Barr virus-specific T-cell cytotoxicity is mediated through the perform pathway in patients with lymphoproliferative disorders after allogeneic bone marrow transplantation
    • Yoshimi, A., I. Tsuge, H. Namizaki, Y. Hoshino, H. Kimura, Y. Takahashi, N. Watanabe, K. Kuzushima, and S. Kojima. 2002. Epstein-Barr virus-specific T-cell cytotoxicity is mediated through the perform pathway in patients with lymphoproliferative disorders after allogeneic bone marrow transplantation. Br. J. Haematol. 116:710-715.
    • (2002) Br. J. Haematol. , vol.116 , pp. 710-715
    • Yoshimi, A.1    Tsuge, I.2    Namizaki, H.3    Hoshino, Y.4    Kimura, H.5    Takahashi, Y.6    Watanabe, N.7    Kuzushima, K.8    Kojima, S.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.