New insights into changes in corneal thickness in healthy mountaineers during a very-high-altitude climb to Mount Muztagh Ata

Archives of Ophthalmology

Volumn 128, Issue 2, 2010, Pages 184-189

  Bosch, Martina Monika ^a   Barthelmes, Daniel ^a   Merz, Tobias Michael ^b   Knecht, Pascal Bruno ^a   Truffer, Frederic ^c   Bloch, Konrad E ^a,d   Thiel, Michael A ^e   Petrig, Benno L ^c   Turk, Alexander J ^a   Schoch, Otto D ^f   Hefti, Urs ^g   Landau, Klara ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b UNIVERSITY OF BERN   (Switzerland)

^c Institut de Recherche en Ophtalmologie   (Switzerland)

^d UNIVERSITY OF ZURICH   (Switzerland)

^e State Hospital Lucerne   (Switzerland)

^f Children's Hospital St Gallen   (Switzerland)

^g Liestal Hospital   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAZOLAMIDE; DEXAMETHASONE; NIFEDIPINE; NONSTEROID ANTIINFLAMMATORY AGENT;

ADULT; ALTITUDE; ALTITUDE ACCLIMATIZATION; ALTITUDE DISEASE; ANTERIOR EYE CHAMBER; ARTICLE; CHINA; COHORT ANALYSIS; CONTACT LENS; CONTROLLED STUDY; CORNEA EDEMA; CORNEA THICKNESS; EYE SWELLING; FEMALE; HEADACHE; HUMAN; HUMAN EXPERIMENT; HYPOXIA; KERATOMILEUSIS; MALE; MEDICAL RESEARCH; MOUNTAINEERING; NORMAL HUMAN; OBSERVATIONAL STUDY; OUTCOME ASSESSMENT; OXYGEN SATURATION; PRIORITY JOURNAL; PROSPECTIVE STUDY; SCORING SYSTEM; TISSUE OXYGENATION; VISUAL ACUITY;

ACCLIMATIZATION; ADULT; ALTITUDE; ALTITUDE SICKNESS; ATMOSPHERIC PRESSURE; CORNEA; CORNEAL EDEMA; FEMALE; HUMANS; MALE; MIDDLE AGED; MOUNTAINEERING; OXYGEN CONSUMPTION; PROSPECTIVE STUDIES; VISUAL ACUITY;

EID: 76349126362     PISSN: 00039950     EISSN: 15383601     Source Type: Journal    
DOI: 10.1001/archophthalmol.2009.385     Document Type: Article

References (29)

1. Hackett PH, Roach RC. High-altitude illness. N Engl J Med. 2001;345(2):107-114.
2. Krakauer J. Into thin air. Outside Magazine. September 1996:46-66.
3. Morris DS, Somner JE, Scott KM, McCormick IJ, Aspinall P, Dhillon B. Corneal thickness at high altitude. Cornea. 2007;26(3):308-311.
4. Morris DS, Somner J, Donald MJ, et al. The eye at altitude. Adv Exp Med Biol. 2006;588:249-270.
5. Bloch KE, Turk AJ, Maggiorini M, et al. Effect of ascent protocol on acute mountain sickness and success at Muztagh Ata 7546 m. High Alt Med Biol. 2009;10(1):25-32.
6. Bosch MM, Barthelmes D, Merz T, et al. High incidence of optic disc swelling at very high altitudes. Arch Ophthalmol. 2008;126(5):644-650.
7. Bosch MM, Merz TM, Barthelmes D, et al. New insights into ocular blood flow at very high altitudes. J Appl Physiol. 2009;106(2):454-460.
8. Ferris FL III, Kassoff A, Bresnick GH, Bailey I. New visual acuity charts for clinical research. Am J Ophthalmol. 1982;94(1):91-96.
9. Sampson JB, Cymerman A, Burse RL, Maher JT, Rock PB. Procedures for the measurement of acute mountain sickness. Aviat Space Environ Med. 1983;54(12, pt 1):1063-1073.
10. Davson H. Hydration of the cornea. J Physiol. 1954;125(1):15-16P.
11. Bonanno JA. Effects of contact lens-induced hypoxia on the physiology of the corneal endothelium. Optom Vis Sci. 2001;78(11):783-790.
12. O'Leary DJ, Wilson G, Henson DB. The effect of anoxia on the human corneal epithelium. Am J Optom Physiol Opt. 1981;58(6):472-476.
13. Wilson G, Fatt I. Thickness of the corneal epithelium during anoxia. Am J Optom Physiol Opt. 1980;57(7):409-412.
14. Wang J, Fonn D, Simpson TL, Jones L. The measurement of corneal epithelial thickness in response to hypoxia using optical coherence tomography. Am J Ophthalmol. 2002;133(3):315-319.
15. Klyce SD. Stromal lactate accumulation can account for corneal oedema osmotically following epithelial hypoxia in the rabbit. J Physiol. 1981;321:49-64.
16. Huff JW. Contact lens-induced edema in vitro: pharmacology and metabolic considerations. Invest Ophthalmol Vis Sci. 1991;32(2):346-353.
17. Huff JW. Effects of sodium lactate on isolated rabbit corneas. Invest Ophthalmol Vis Sci. 1990;31(5):942-947.
18. Cohen SR, Polse KA, Brand RJ, Bonanno JA. Stromal acidosis affects corneal hydration control. Invest Ophthalmol Vis Sci. 1992;33(1):134-142.
19. Weissman BA, Fatt I. External hypoxia and corneal hydration dynamics. Am J Optom Physiol Opt. 1982;59(1):1-4.
20. Klyce SD, Farris RL, Dabezies OH. Corneal oxygenation in contact lens wearers. In: Dabezies OH, ed. Contact Lenses: The CLAO Guide to Basic Science and Clinical Practice. Orlando, FL: Grune & Stratton; 1984.
21. McLaren JW, Dinslage S, Dillon JP, Roberts JE, Brubaker RF. Measuring oxygen tension in the anterior chamber of rabbits. Invest Ophthalmol Vis Sci. 1998;39(10):1899-1909.
22. Polse KA, Brand R, Mandell R, Vastine D, Demartini D, Flom R. Age differences in corneal hydration control. Invest Ophthalmol Vis Sci. 1989;30(3):392-399.
23. Cheung AK, Siu AW, Cheung DW, Mo EC. Production of hypoxia-induced corneal edema in aged eyes. Yan Ke Xue Bao. 2004;20(1):1-5.
24. Sun XC, Li J, Cui M, Bonanno JA. Role of carbonic anhydrase IV in corneal endothelial HCO3-transport. Invest Ophthalmol Vis Sci. 2008;49(3):1048-1055.
25. Nielsen CB. The effect of carbonic anhydrase inhibition on central corneal thickness after cataract extraction. Acta Ophthalmol (Copenh). 1980;58(6):985-990.
26. Srinivas SP, Ong A, Zhai CB, Bonanno JA. Inhibition of carbonic anhydrase activity in cultured bovine corneal endothelial cells by dorzolamide. Invest Ophthalmol Vis Sci. 2002;43(10):3273-3278.
27. Wirtitsch MG, Findl O, Heinzl H, Drexler W. Effect of dorzolamide hydrochloride on central corneal thickness in humans with cornea guttata. Arch Ophthalmol. 2007;125(10):1345-1350.
28. Marsich MW, Bullimore MA. The repeatability of corneal thickness measures. Cornea. 2000;19(6):792-795.
29. Christensen A, Narvaez J, Zimmerman G. Comparison of central corneal thickness measurements by ultrasound pachymetry, konan noncontact optical pachymetry, and orbscan pachymetry. Cornea. 2008;27(8):862-865.