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Volumn 105, Issue 2, 2010, Pages 275-279

Gut microbes: From bugs to drugs

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[No Author keywords available]

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PROBIOTIC AGENT;

EID: 76349083598     PISSN: 00029270     EISSN: 15720241     Source Type: Journal    
DOI: 10.1038/ajg.2009.729     Document Type: Review
Times cited : (43)

References (35)
  • 1
    • 68049100846 scopus 로고    scopus 로고
    • Risk factor epidemiology:Science or non-science?
    • Taragon Press:Whithorn
    • Skrabanek P. Risk factor epidemiology:Science or non-science? In:False Premises False Promises. Taragon Press:Whithorn, 1999, pp 153-63.
    • (1999) False Premises False Promises , pp. 153-63
    • Skrabanek, P.1
  • 2
    • 44349124113 scopus 로고    scopus 로고
    • The genetics and immunopathogenesis of infl ammatory bowel disease
    • Cho JH. The genetics and immunopathogenesis of infl ammatory bowel disease. Nat Rev Immunol 2008;8:458-466
    • (2008) Nat Rev Immunol , vol.8 , pp. 458-466
    • Cho, J.H.1
  • 3
    • 37249006192 scopus 로고    scopus 로고
    • New links to the pathogenesis of Crohn disease provided by genome-wide association scans
    • Mathew CG. New links to the pathogenesis of Crohn disease provided by genome-wide association scans. Nat Rev Genet 2008;9:9-14.
    • (2008) Nat Rev Genet , vol.9 , pp. 9-14
    • Mathew, C.G.1
  • 4
    • 50249143099 scopus 로고    scopus 로고
    • Disorders of a modern lifestyle:reconciling the epidemiology of infl ammatory bowel diseases
    • Bernstein CN, Shanahan F. Disorders of a modern lifestyle:reconciling the epidemiology of infl ammatory bowel diseases. Gut 2008;57:1185-1191
    • (2008) Gut , vol.57 , pp. 1185-1191
    • Bernstein, C.N.1    Shanahan, F.2
  • 5
    • 33745594044 scopus 로고    scopus 로고
    • The gutflora as a forgotten organ
    • O'Hara AM, Shanahan F. The gutflora as a forgotten organ. EMBO Rep, 2006, 7, 688-693
    • (2006) EMBO Rep , vol.7 , pp. 688-693
    • O'Hara, A.M.1    Shanahan, F.2
  • 6
    • 69949110703 scopus 로고    scopus 로고
    • Therapeutic implications of manipulating and mining the microbiota
    • Shanahan F. Therapeutic implications of manipulating and mining the microbiota. J Physiol 2009;587 (Pt 17):4175-4179
    • (2009) J Physiol , vol.587 , Issue.PART 17 , pp. 4175-4179
    • Shanahan, F.1
  • 7
    • 67349250428 scopus 로고    scopus 로고
    • The gut microbiota shapes intestinal immune responses during health and disease
    • Round JL, Mazmanian SK. The gut microbiota shapes intestinal immune responses during health and disease. Nat Rev Immunol 2009;9:313-323
    • (2009) Nat Rev Immunol , vol.9 , pp. 313-323
    • Round, J.L.1    Mazmanian, S.K.2
  • 8
    • 35348968286 scopus 로고    scopus 로고
    • The human microbiome project
    • Turnbaugh PJ, Ley RE, Hamady M et al. The human microbiome project. Nature 2007;449:804-810
    • (2007) Nature , vol.449 , pp. 804-810
    • Turnbaugh, P.J.1    Ley, R.E.2    Hamady, M.3
  • 9
    • 8144226856 scopus 로고    scopus 로고
    • The gut microbiota as an environmental factor that regulates fat storage
    • Backhed F, Ding H, Wang T et al. The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci USA 2004;101:15718-15723
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 15718-15723
    • Backhed, F.1    Ding, H.2    Wang, T.3
  • 10
    • 54549122338 scopus 로고    scopus 로고
    • Innate immunity and intestinal microbiota in the development of Type 1 diabetes
    • Wen L, Ley RE, Volchkov PY et al. Innate immunity and intestinal microbiota in the development of Type 1 diabetes. Nature 2008;455:1109-1113
    • (2008) Nature , vol.455 , pp. 1109-1113
    • Wen, L.1    Ley, R.E.2    Volchkov, P.Y.3
  • 11
    • 67650604595 scopus 로고    scopus 로고
    • The role of the gut microbiota in energy metabolism and metabolic disease
    • Cani PD, Delzenne NM. The role of the gut microbiota in energy metabolism and metabolic disease. Curr Pharm Design 2009;15:1546-1558
    • (2009) Curr Pharm Design , vol.15 , pp. 1546-1558
    • Cani, P.D.1    Delzenne, N.M.2
  • 12
    • 41149099000 scopus 로고    scopus 로고
    • Symbiotic gut microbes modulate human metabolic phenotypes
    • Li M, Wang B, Zhang M et al. Symbiotic gut microbes modulate human metabolic phenotypes. Proc Natl Acad Sci USA 2008;105:2117-2122
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 2117-2122
    • Li, M.1    Wang, B.2    Zhang, M.3
  • 13
    • 77957601459 scopus 로고    scopus 로고
    • Pharmabiotics:bioactives from mining host-microbe-dietary interactions
    • Shanahan F, Stanton C, Ross P et al. Pharmabiotics:bioactives from mining host-microbe-dietary interactions. Funct Food Rev 2009;1:1-6.
    • (2009) Funct Food Rev , vol.1 , pp. 1-6
    • Shanahan, F.1    Stanton, C.2    Ross, P.3
  • 14
    • 34447517430 scopus 로고    scopus 로고
    • Evidence for the use of probiotics and prebiotics in infl ammatory bowel disease:a review of clinical trials
    • Hedin C, Whelan K, Lindsay JO. Evidence for the use of probiotics and prebiotics in infl ammatory bowel disease:a review of clinical trials. Proc Nutr Soc 2007;66:307-315
    • (2007) Proc Nutr Soc , vol.66 , pp. 307-315
    • Hedin, C.1    Whelan, K.2    Lindsay, J.O.3
  • 15
    • 34250622074 scopus 로고    scopus 로고
    • Bacteriocin production as a mechanism for the antiinfective activity of Lactobacillus salivarius UCC118
    • Corr SC, Li Y, Riedel CU et al. Bacteriocin production as a mechanism for the antiinfective activity of Lactobacillus salivarius UCC118. Proc Natl Acad Sci USA 2007;104:7617-7621
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 7617-7621
    • Corr, S.C.1    Li, Y.2    Riedel, C.U.3
  • 16
    • 39449089584 scopus 로고    scopus 로고
    • Probiotic prophylaxis in predicted severe acute pancreatitis:a randomised, double-blind, placebocontrolled trial
    • Erratum in:Lancet 2008;371
    • Besselink MG, van Santvoort HC, Buskens E et al. Probiotic prophylaxis in predicted severe acute pancreatitis:a randomised, double-blind, placebocontrolled trial. Lancet 2008;371:651-9. Erratum in:Lancet 2008;371:1246.
    • (2008) Lancet , vol.371 , pp. 651-659
    • Besselink, M.G.1    Van Santvoort, H.C.2    Buskens, E.3
  • 17
    • 33845508443 scopus 로고    scopus 로고
    • Genomic and metabolic studies of the impact of probiotics on a model gut symbiont and host
    • Sonnenburg JL, Chen CTL, Gordon JI. Genomic and metabolic studies of the impact of probiotics on a model gut symbiont and host. PLoS Biol 2006;4:2213-2226
    • (2006) PLoS Biol , vol.4 , pp. 2213-2226
    • Sonnenburg, J.L.1    Chen, C.T.L.2    Gordon, J.I.3
  • 18
    • 65249149643 scopus 로고    scopus 로고
    • Characterizing a model human gut microbiota composed of members of its two dominant bacterial phyla
    • Mahowald MA, Rey FE, Seedorf H et al. Characterizing a model human gut microbiota composed of members of its two dominant bacterial phyla. Proc Natl Acad Sci USA 2009;106:5859-5864
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 5859-5864
    • Mahowald, M.A.1    Rey, F.E.2    Seedorf, H.3
  • 19
    • 65549108323 scopus 로고    scopus 로고
    • The metabolic activity of the enteric microbiota infl uences the fatty acid composition of murine and porcine liver and adipose tissues
    • Wall R, Ross RP, Shanahan F et al. The metabolic activity of the enteric microbiota infl uences the fatty acid composition of murine and porcine liver and adipose tissues. Am J Clin Nutr 2009;89:1393-1401
    • (2009) Am J Clin Nutr , vol.89 , pp. 1393-1401
    • Wall, R.1    Ross, R.P.2    Shanahan, F.3
  • 20
    • 0029926387 scopus 로고    scopus 로고
    • Epidemiologic analysis of Crohn disease in Japan:increased dietary intake of n-6 polyunsaturated fatty acids and animal protein relates to the increased incidence of Crohn disease in Japan
    • Shoda R, Matsueda K, Yamato S et al. Epidemiologic analysis of Crohn disease in Japan:increased dietary intake of n-6 polyunsaturated fatty acids and animal protein relates to the increased incidence of Crohn disease in Japan. Am J Clin Nutr 1996;63:741-745
    • (1996) Am J Clin Nutr , vol.63 , pp. 741-745
    • Shoda, R.1    Matsueda, K.2    Yamato, S.3
  • 21
    • 34047127580 scopus 로고    scopus 로고
    • The drug development crisis:effi ciency and safety
    • Caskey CT. The drug development crisis:effi ciency and safety. Annu Rev Med 2007;58:1-16.
    • (2007) Annu Rev Med , vol.58 , pp. 1-16
    • Caskey, C.T.1
  • 22
    • 0028789199 scopus 로고
    • Drug development in gastroenterology-the changing view of industry
    • Parsons ME, Garner A. Drug development in gastroenterology-the changing view of industry. Aliment Pharmacol Ther 1995;9:457-463
    • (1995) Aliment Pharmacol Ther , vol.9 , pp. 457-463
    • Parsons, M.E.1    Garner, A.2
  • 23
    • 56649115765 scopus 로고    scopus 로고
    • The importance of biodiversity to medicine
    • Bernstein AS, Ludwig DS. The importance of biodiversity to medicine. JAMA 2008;200:2297-2299
    • (2008) JAMA , vol.200 , pp. 2297-2299
    • Bernstein, A.S.1    Ludwig, D.S.2
  • 24
    • 46149125505 scopus 로고    scopus 로고
    • The gut microbiota and disease-an inner repository for drug discovery
    • Shanahan F, Kiely B. The gut microbiota and disease-an inner repository for drug discovery. Drug Discov Today Th er Strateg 2007;4:195-200.
    • (2007) Drug Discov Today Th Er Strateg , vol.4 , pp. 195-200
    • Shanahan, F.1    Kiely, B.2
  • 25
    • 53349173070 scopus 로고    scopus 로고
    • Specifi c microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine
    • Ivanov II, Frutos Rde L, Manel N et al. Specifi c microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine. Cell Host Microbe 2008;4:337-349
    • (2008) Cell Host Microbe , vol.4 , pp. 337-349
    • Ivanov, I.I.1    Frutos Rde, L.2    Manel, N.3
  • 26
    • 56749146467 scopus 로고    scopus 로고
    • Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis
    • Bouskra D, Bré zillon C, Bérard M et al. Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis. Nature 2008;456:507-510
    • (2008) Nature , vol.456 , pp. 507-510
    • Bouskra, D.1    Brézillon, C.2    Bérard, M.3
  • 27
    • 22144490199 scopus 로고    scopus 로고
    • An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system
    • Mazmanian SK, Liu CH, Tzianabos AO et al. An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system. Cell 2005;122:107-118
    • (2005) Cell , vol.122 , pp. 107-118
    • Mazmanian, S.K.1    Liu, C.H.2    Tzianabos, A.O.3
  • 28
    • 10744233159 scopus 로고    scopus 로고
    • Toll-like receptor 9 signaling mediates the anti-infl ammatory eff ects of probiotics in murine experimental colitis
    • Rachmilewitz D, Katakura K, Karmeli F et al. Toll-like receptor 9 signaling mediates the anti-infl ammatory eff ects of probiotics in murine experimental colitis. Gastroenterology 2004;126:520-528
    • (2004) Gastroenterology , vol.126 , pp. 520-528
    • Rachmilewitz, D.1    Katakura, K.2    Karmeli, F.3
  • 29
    • 34249893108 scopus 로고    scopus 로고
    • The Bacillus subtilis quorum-sensing molecule CSF contributes to intestinal homeostasis via OCTN2, a host cell membrane transporter
    • Fujiya M, Musch MW, Nakagawa Y et al. The Bacillus subtilis quorum-sensing molecule CSF contributes to intestinal homeostasis via OCTN2, a host cell membrane transporter. Cell Host Microbe 2007;1:299-308.
    • (2007) Cell Host Microbe , vol.1 , pp. 299-308
    • Fujiya, M.1    Musch, M.W.2    Nakagawa, Y.3
  • 30
    • 33847021973 scopus 로고    scopus 로고
    • Soluble proteins produced by probiotic bacteria regulate intestinal epithelial cell survival and growth
    • Yan F, Cao H, Cover TL, Whitehead R et al. Soluble proteins produced by probiotic bacteria regulate intestinal epithelial cell survival and growth. Gastroenterology 2007;132:562-575
    • (2007) Gastroenterology , vol.132 , pp. 562-575
    • Yan, F.1    Cao, H.2    Cover, T.L.3    Whitehead, R.4
  • 31
    • 44449106055 scopus 로고    scopus 로고
    • A microbial symbiosis factor prevents intestinal infl ammatory disease
    • Mazmanian SK, Round JL, Kasper DL. A microbial symbiosis factor prevents intestinal infl ammatory disease. Nature 2008;453:620-625
    • (2008) Nature , vol.453 , pp. 620-625
    • Mazmanian, S.K.1    Round, J.L.2    Kasper, D.L.3
  • 32
    • 27244436751 scopus 로고    scopus 로고
    • Bacteriocins:developing innate immunity for food
    • Cotter PD, Hill C, Ross RP. Bacteriocins:developing innate immunity for food. Nat Rev Microbiol 2005;3:777-788
    • (2005) Nat Rev Microbiol , vol.3 , pp. 777-788
    • Cotter, P.D.1    Hill, C.2    Ross, R.P.3
  • 33
    • 33645099061 scopus 로고    scopus 로고
    • A preliminary study of the eff ect of probiotic Streptococcus salivarius K12 on oral malodour parameters
    • Burton JP, Chilcott CN, Moore CJ et al. A preliminary study of the eff ect of probiotic Streptococcus salivarius K12 on oral malodour parameters. J Appl Microbiol 2006;100:754-764
    • (2006) J Appl Microbiol , vol.100 , pp. 754-764
    • Burton, J.P.1    Chilcott, C.N.2    Moore, C.J.3
  • 34
    • 34447250021 scopus 로고    scopus 로고
    • O ' Connor PM et al. Antimicrobial activity of lacticin 3147 against clinical Clostridium diffi cile strains
    • Rea MC, Clayton E, O ' Connor PM et al. Antimicrobial activity of lacticin 3147 against clinical Clostridium diffi cile strains. J Med Microbiol 2007;56:940-946
    • (2007) J Med Microbiol , vol.56 , pp. 940-946
    • Rea, M.C.1    Clayton, E.2
  • 35
    • 55249105923 scopus 로고    scopus 로고
    • Clostridium diffi cile-more difficult than ever
    • Kelly CP, LaMont JT. Clostridium diffi cile-more difficult than ever. N Engl J Med 2009;359:1932-1940
    • (2009) N Engl J Med , vol.359 , pp. 1932-1940
    • Kelly, C.P.1    Lamont, J.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.