-
1
-
-
68049100846
-
Risk factor epidemiology:Science or non-science?
-
Taragon Press:Whithorn
-
Skrabanek P. Risk factor epidemiology:Science or non-science? In:False Premises False Promises. Taragon Press:Whithorn, 1999, pp 153-63.
-
(1999)
False Premises False Promises
, pp. 153-63
-
-
Skrabanek, P.1
-
2
-
-
44349124113
-
The genetics and immunopathogenesis of infl ammatory bowel disease
-
Cho JH. The genetics and immunopathogenesis of infl ammatory bowel disease. Nat Rev Immunol 2008;8:458-466
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 458-466
-
-
Cho, J.H.1
-
3
-
-
37249006192
-
New links to the pathogenesis of Crohn disease provided by genome-wide association scans
-
Mathew CG. New links to the pathogenesis of Crohn disease provided by genome-wide association scans. Nat Rev Genet 2008;9:9-14.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 9-14
-
-
Mathew, C.G.1
-
4
-
-
50249143099
-
Disorders of a modern lifestyle:reconciling the epidemiology of infl ammatory bowel diseases
-
Bernstein CN, Shanahan F. Disorders of a modern lifestyle:reconciling the epidemiology of infl ammatory bowel diseases. Gut 2008;57:1185-1191
-
(2008)
Gut
, vol.57
, pp. 1185-1191
-
-
Bernstein, C.N.1
Shanahan, F.2
-
5
-
-
33745594044
-
The gutflora as a forgotten organ
-
O'Hara AM, Shanahan F. The gutflora as a forgotten organ. EMBO Rep, 2006, 7, 688-693
-
(2006)
EMBO Rep
, vol.7
, pp. 688-693
-
-
O'Hara, A.M.1
Shanahan, F.2
-
6
-
-
69949110703
-
Therapeutic implications of manipulating and mining the microbiota
-
Shanahan F. Therapeutic implications of manipulating and mining the microbiota. J Physiol 2009;587 (Pt 17):4175-4179
-
(2009)
J Physiol
, vol.587
, Issue.PART 17
, pp. 4175-4179
-
-
Shanahan, F.1
-
7
-
-
67349250428
-
The gut microbiota shapes intestinal immune responses during health and disease
-
Round JL, Mazmanian SK. The gut microbiota shapes intestinal immune responses during health and disease. Nat Rev Immunol 2009;9:313-323
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 313-323
-
-
Round, J.L.1
Mazmanian, S.K.2
-
9
-
-
8144226856
-
The gut microbiota as an environmental factor that regulates fat storage
-
Backhed F, Ding H, Wang T et al. The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci USA 2004;101:15718-15723
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 15718-15723
-
-
Backhed, F.1
Ding, H.2
Wang, T.3
-
10
-
-
54549122338
-
Innate immunity and intestinal microbiota in the development of Type 1 diabetes
-
Wen L, Ley RE, Volchkov PY et al. Innate immunity and intestinal microbiota in the development of Type 1 diabetes. Nature 2008;455:1109-1113
-
(2008)
Nature
, vol.455
, pp. 1109-1113
-
-
Wen, L.1
Ley, R.E.2
Volchkov, P.Y.3
-
11
-
-
67650604595
-
The role of the gut microbiota in energy metabolism and metabolic disease
-
Cani PD, Delzenne NM. The role of the gut microbiota in energy metabolism and metabolic disease. Curr Pharm Design 2009;15:1546-1558
-
(2009)
Curr Pharm Design
, vol.15
, pp. 1546-1558
-
-
Cani, P.D.1
Delzenne, N.M.2
-
12
-
-
41149099000
-
Symbiotic gut microbes modulate human metabolic phenotypes
-
Li M, Wang B, Zhang M et al. Symbiotic gut microbes modulate human metabolic phenotypes. Proc Natl Acad Sci USA 2008;105:2117-2122
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 2117-2122
-
-
Li, M.1
Wang, B.2
Zhang, M.3
-
13
-
-
77957601459
-
Pharmabiotics:bioactives from mining host-microbe-dietary interactions
-
Shanahan F, Stanton C, Ross P et al. Pharmabiotics:bioactives from mining host-microbe-dietary interactions. Funct Food Rev 2009;1:1-6.
-
(2009)
Funct Food Rev
, vol.1
, pp. 1-6
-
-
Shanahan, F.1
Stanton, C.2
Ross, P.3
-
14
-
-
34447517430
-
Evidence for the use of probiotics and prebiotics in infl ammatory bowel disease:a review of clinical trials
-
Hedin C, Whelan K, Lindsay JO. Evidence for the use of probiotics and prebiotics in infl ammatory bowel disease:a review of clinical trials. Proc Nutr Soc 2007;66:307-315
-
(2007)
Proc Nutr Soc
, vol.66
, pp. 307-315
-
-
Hedin, C.1
Whelan, K.2
Lindsay, J.O.3
-
15
-
-
34250622074
-
Bacteriocin production as a mechanism for the antiinfective activity of Lactobacillus salivarius UCC118
-
Corr SC, Li Y, Riedel CU et al. Bacteriocin production as a mechanism for the antiinfective activity of Lactobacillus salivarius UCC118. Proc Natl Acad Sci USA 2007;104:7617-7621
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 7617-7621
-
-
Corr, S.C.1
Li, Y.2
Riedel, C.U.3
-
16
-
-
39449089584
-
Probiotic prophylaxis in predicted severe acute pancreatitis:a randomised, double-blind, placebocontrolled trial
-
Erratum in:Lancet 2008;371
-
Besselink MG, van Santvoort HC, Buskens E et al. Probiotic prophylaxis in predicted severe acute pancreatitis:a randomised, double-blind, placebocontrolled trial. Lancet 2008;371:651-9. Erratum in:Lancet 2008;371:1246.
-
(2008)
Lancet
, vol.371
, pp. 651-659
-
-
Besselink, M.G.1
Van Santvoort, H.C.2
Buskens, E.3
-
17
-
-
33845508443
-
Genomic and metabolic studies of the impact of probiotics on a model gut symbiont and host
-
Sonnenburg JL, Chen CTL, Gordon JI. Genomic and metabolic studies of the impact of probiotics on a model gut symbiont and host. PLoS Biol 2006;4:2213-2226
-
(2006)
PLoS Biol
, vol.4
, pp. 2213-2226
-
-
Sonnenburg, J.L.1
Chen, C.T.L.2
Gordon, J.I.3
-
18
-
-
65249149643
-
Characterizing a model human gut microbiota composed of members of its two dominant bacterial phyla
-
Mahowald MA, Rey FE, Seedorf H et al. Characterizing a model human gut microbiota composed of members of its two dominant bacterial phyla. Proc Natl Acad Sci USA 2009;106:5859-5864
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 5859-5864
-
-
Mahowald, M.A.1
Rey, F.E.2
Seedorf, H.3
-
19
-
-
65549108323
-
The metabolic activity of the enteric microbiota infl uences the fatty acid composition of murine and porcine liver and adipose tissues
-
Wall R, Ross RP, Shanahan F et al. The metabolic activity of the enteric microbiota infl uences the fatty acid composition of murine and porcine liver and adipose tissues. Am J Clin Nutr 2009;89:1393-1401
-
(2009)
Am J Clin Nutr
, vol.89
, pp. 1393-1401
-
-
Wall, R.1
Ross, R.P.2
Shanahan, F.3
-
20
-
-
0029926387
-
Epidemiologic analysis of Crohn disease in Japan:increased dietary intake of n-6 polyunsaturated fatty acids and animal protein relates to the increased incidence of Crohn disease in Japan
-
Shoda R, Matsueda K, Yamato S et al. Epidemiologic analysis of Crohn disease in Japan:increased dietary intake of n-6 polyunsaturated fatty acids and animal protein relates to the increased incidence of Crohn disease in Japan. Am J Clin Nutr 1996;63:741-745
-
(1996)
Am J Clin Nutr
, vol.63
, pp. 741-745
-
-
Shoda, R.1
Matsueda, K.2
Yamato, S.3
-
21
-
-
34047127580
-
The drug development crisis:effi ciency and safety
-
Caskey CT. The drug development crisis:effi ciency and safety. Annu Rev Med 2007;58:1-16.
-
(2007)
Annu Rev Med
, vol.58
, pp. 1-16
-
-
Caskey, C.T.1
-
22
-
-
0028789199
-
Drug development in gastroenterology-the changing view of industry
-
Parsons ME, Garner A. Drug development in gastroenterology-the changing view of industry. Aliment Pharmacol Ther 1995;9:457-463
-
(1995)
Aliment Pharmacol Ther
, vol.9
, pp. 457-463
-
-
Parsons, M.E.1
Garner, A.2
-
23
-
-
56649115765
-
The importance of biodiversity to medicine
-
Bernstein AS, Ludwig DS. The importance of biodiversity to medicine. JAMA 2008;200:2297-2299
-
(2008)
JAMA
, vol.200
, pp. 2297-2299
-
-
Bernstein, A.S.1
Ludwig, D.S.2
-
24
-
-
46149125505
-
The gut microbiota and disease-an inner repository for drug discovery
-
Shanahan F, Kiely B. The gut microbiota and disease-an inner repository for drug discovery. Drug Discov Today Th er Strateg 2007;4:195-200.
-
(2007)
Drug Discov Today Th Er Strateg
, vol.4
, pp. 195-200
-
-
Shanahan, F.1
Kiely, B.2
-
25
-
-
53349173070
-
Specifi c microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine
-
Ivanov II, Frutos Rde L, Manel N et al. Specifi c microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine. Cell Host Microbe 2008;4:337-349
-
(2008)
Cell Host Microbe
, vol.4
, pp. 337-349
-
-
Ivanov, I.I.1
Frutos Rde, L.2
Manel, N.3
-
26
-
-
56749146467
-
Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis
-
Bouskra D, Bré zillon C, Bérard M et al. Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis. Nature 2008;456:507-510
-
(2008)
Nature
, vol.456
, pp. 507-510
-
-
Bouskra, D.1
Brézillon, C.2
Bérard, M.3
-
27
-
-
22144490199
-
An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system
-
Mazmanian SK, Liu CH, Tzianabos AO et al. An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system. Cell 2005;122:107-118
-
(2005)
Cell
, vol.122
, pp. 107-118
-
-
Mazmanian, S.K.1
Liu, C.H.2
Tzianabos, A.O.3
-
28
-
-
10744233159
-
Toll-like receptor 9 signaling mediates the anti-infl ammatory eff ects of probiotics in murine experimental colitis
-
Rachmilewitz D, Katakura K, Karmeli F et al. Toll-like receptor 9 signaling mediates the anti-infl ammatory eff ects of probiotics in murine experimental colitis. Gastroenterology 2004;126:520-528
-
(2004)
Gastroenterology
, vol.126
, pp. 520-528
-
-
Rachmilewitz, D.1
Katakura, K.2
Karmeli, F.3
-
29
-
-
34249893108
-
The Bacillus subtilis quorum-sensing molecule CSF contributes to intestinal homeostasis via OCTN2, a host cell membrane transporter
-
Fujiya M, Musch MW, Nakagawa Y et al. The Bacillus subtilis quorum-sensing molecule CSF contributes to intestinal homeostasis via OCTN2, a host cell membrane transporter. Cell Host Microbe 2007;1:299-308.
-
(2007)
Cell Host Microbe
, vol.1
, pp. 299-308
-
-
Fujiya, M.1
Musch, M.W.2
Nakagawa, Y.3
-
30
-
-
33847021973
-
Soluble proteins produced by probiotic bacteria regulate intestinal epithelial cell survival and growth
-
Yan F, Cao H, Cover TL, Whitehead R et al. Soluble proteins produced by probiotic bacteria regulate intestinal epithelial cell survival and growth. Gastroenterology 2007;132:562-575
-
(2007)
Gastroenterology
, vol.132
, pp. 562-575
-
-
Yan, F.1
Cao, H.2
Cover, T.L.3
Whitehead, R.4
-
31
-
-
44449106055
-
A microbial symbiosis factor prevents intestinal infl ammatory disease
-
Mazmanian SK, Round JL, Kasper DL. A microbial symbiosis factor prevents intestinal infl ammatory disease. Nature 2008;453:620-625
-
(2008)
Nature
, vol.453
, pp. 620-625
-
-
Mazmanian, S.K.1
Round, J.L.2
Kasper, D.L.3
-
32
-
-
27244436751
-
Bacteriocins:developing innate immunity for food
-
Cotter PD, Hill C, Ross RP. Bacteriocins:developing innate immunity for food. Nat Rev Microbiol 2005;3:777-788
-
(2005)
Nat Rev Microbiol
, vol.3
, pp. 777-788
-
-
Cotter, P.D.1
Hill, C.2
Ross, R.P.3
-
33
-
-
33645099061
-
A preliminary study of the eff ect of probiotic Streptococcus salivarius K12 on oral malodour parameters
-
Burton JP, Chilcott CN, Moore CJ et al. A preliminary study of the eff ect of probiotic Streptococcus salivarius K12 on oral malodour parameters. J Appl Microbiol 2006;100:754-764
-
(2006)
J Appl Microbiol
, vol.100
, pp. 754-764
-
-
Burton, J.P.1
Chilcott, C.N.2
Moore, C.J.3
-
34
-
-
34447250021
-
O ' Connor PM et al. Antimicrobial activity of lacticin 3147 against clinical Clostridium diffi cile strains
-
Rea MC, Clayton E, O ' Connor PM et al. Antimicrobial activity of lacticin 3147 against clinical Clostridium diffi cile strains. J Med Microbiol 2007;56:940-946
-
(2007)
J Med Microbiol
, vol.56
, pp. 940-946
-
-
Rea, M.C.1
Clayton, E.2
-
35
-
-
55249105923
-
Clostridium diffi cile-more difficult than ever
-
Kelly CP, LaMont JT. Clostridium diffi cile-more difficult than ever. N Engl J Med 2009;359:1932-1940
-
(2009)
N Engl J Med
, vol.359
, pp. 1932-1940
-
-
Kelly, C.P.1
Lamont, J.T.2
|