Late Effects After Radiotherapy for Locally Advanced Cervical Cancer: Comparison of Two Brachytherapy Schedules and Effect of Dose Delivered Weekly

International Journal of Radiation Oncology Biology Physics

Volumn 76, Issue 3, 2010, Pages 713-718

  Hellebust, Taran Paulsen ^a,c   Kristensen, Gunnar B ^a,b   Olsen, Dag Rune ^b,c  

^a INSTITUTE OF CANCER RESEARCH   (Norway)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

^c UNIVERSITY OF OSLO   (Norway)

Author keywords

Cervical cancer; consequential late effects; high dose rate brachytherapy; late complications

Indexed keywords

BRACHYTHERAPY; CERVICAL CANCERS; CUMULATIVE INCIDENCE; DOSE LEVELS; DOSE RESPONSE RELATIONSHIPS; DOSE-VOLUME HISTOGRAMS; EQUIVALENT DOSE; EXTERNAL BEAM RADIOTHERAPY; HIGH DOSE RATE; HIGH-DOSE RATE BRACHYTHERAPY; INTERNATIONAL COMMISSION; KAPLAN-MEIER; LATE EFFECTS; RADIATION UNIT; SURVIVAL ANALYSIS; THREE DIMENSIONAL IMAGING; THREE-DIMENSIONAL DATA; TOLERANCE LEVELS;

ONCOLOGY; PATIENT MONITORING; THREE DIMENSIONAL;

RADIOTHERAPY;

ADULT; ADVANCED CANCER; AGED; ARTICLE; BRACHYTHERAPY; CANCER PATIENT; COMPARATIVE STUDY; CONTROLLED STUDY; DOSIMETRY; EXTERNAL BEAM RADIOTHERAPY; FEMALE; GASTROINTESTINAL TOXICITY; HUMAN; MAJOR CLINICAL STUDY; MORBIDITY; PRIORITY JOURNAL; RADIATION DOSE; RADIATION DOSE FRACTIONATION; RADIATION INJURY; RADIATION RESPONSE; THERAPY EFFECT; UROGENITAL TRACT DISEASE; UTERINE CERVIX CANCER;

ADULT; AGED; AGED, 80 AND OVER; BRACHYTHERAPY; DOSE FRACTIONATION; FEMALE; HUMANS; MIDDLE AGED; RADIATION INJURIES; RADIATION TOLERANCE; RECTUM; TIME FACTORS; URINARY BLADDER; UTERINE CERVICAL NEOPLASMS;

EID: 76249128770     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2009.02.024     Document Type: Article

References (33)

1. Petereit D.G., and Pearcey R. Literature analysis of high dose rate brachytherapy fractionation schedules in the treatment of cervical cancer: Is there an optimal fractionation schedule?. Int J Radiat Oncol Biol Phys 43 (1999) 359-366
2. Pötter R., Dimopoulos J., George P., et al. Clinical impact of MRI assisted dose volume adaptation and dose escalation in brachytherapy of locally advanced cervix cancer. Radiother Oncol 83 (2007) 148-155
3. Ota T., Takeshima N., Tabata T., et al. Treatment of squamous cell carcinoma of the uterine cervix with radiation therapy alone: Long-term survival, late complications, and incidence of second cancers. Br J Cancer 97 (2007) 1058-1062
4. Noda S., Ohno T., Kato S., et al. Late rectal complications evaluated by computed tomography-based dose calculations in patients with cervical carcinoma undergoing high-dose-rate brachytherapy. Int J Radiat Oncol Biol Phys 69 (2007) 118-124
5. Wang C.J., Huang E.Y., Sun L.M., et al. Clinical comparison of two linear-quadratic model-based isoeffect fractionation schemes of high-dose-rate intracavitary brachytherapy for cervical cancer. Int J Radiat Oncol Biol Phys 59 (2004) 179-189
6. Ferrigno R., Novaes P.E., Pellizzon A.C., et al. High-dose-rate brachytherapy in the treatment of uterine cervix cancer: Analysis of dose effectiveness and late complications. Int J Radiat Oncol Biol Phys 50 (2001) 1123-1135
7. Chen S.W., Ljang J.A., Yeh L.S., et al. Comparative study of reference points by dosimetric analyses for late complications after uniform external radiotherapy and high-dose-rate brachytherapy for cervical cancer. Int J Radiat Oncol Biol Phys 60 (2004) 663-671
8. Mosalaei A., Mohammadianpanah S., and Ahmadloo O.N. High-dose rate brachytherapy in the treatment of carcinoma of uterine cervix: Twenty-year experience with cobalt after-loading system. Int J Gynecol Cancer 16 (2006) 1101-1105
9. Weiss E., Hirnle P., Arnold-Bofinger H., et al. Therapeutic outcome and relation of acute and late side effects in the adjuvant radiotherapy of endometrial carcinoma stage I and II. Radiother Oncol 53 (1999) 37-44
10. Wang C.J., Leung S.W., Chen H.C., et al. The correlation of acute toxicity and late rectal injury in radiotherapy for cervical carcinoma: Evidence suggestive of consequential late effect (CQLE). Int J Radiat Oncol Biol Phys 40 (1998) 85-91
11. Schultheiss T.E., Lee W.R., Hunt M.A., et al. Late GI and GU complications in the treatment of prostate cancer. Int J Radiat Oncol Biol Phys 37 (1997) 3-11
12. Dörr W., and Hendry J.H. Consequential late effects in normal tissues. Radiother Oncol 61 (2001) 223-231
13. Wilkinson J.M., Moore C.J., Notley H.M., et al. The use of Selectron afterloading equipment to simulate and extend the Manchester System for intracavitary therapy of the cervix uteri. Br J Radiol 56 (1983) 409-414
14. International Commission on Radiation Units and Measurements. ICRU report 38: Dose and volume specification for reporting intracavitary therapy in gynecology (1985), ICRU, Washington, DC
15. Sakata K.I., Nagakura H., Oouchi A., et al. High-dose-rate intracavitary brachytherapy: Results of analyses of late rectal complications. Int J Radiat Oncol Biol Phys 54 (2002) 1369-1376
16. Cox J.D., Stetz J., and Pajak T.F. Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC). Int J Radiat Oncol Biol Phys 31 (1995) 1341-1346
17. Huang E.Y., Wang C.J., Hsu H.C., et al. Dosimetric factors predicting severe radiation-induced bowel complications in patients with cervical cancer: Combined effect of external parametrial dose and cumulative rectal dose. Gynecol Oncol 95 (2004) 101-108
18. Chen S.W., Liang J.A., Yang S.N., et al. The prediction of late rectal complications following the treatment of uterine cervical cancer by high-dose-rate brachytherapy. Int J Radiat Oncol Biol Phys 47 (2000) 955-961
19. Ogino I., Kitamura T., Okamoto N., et al. Late rectal complication following high dose rate intracavitary brachytherapy in cancer of the cervix. Int J Radiat Oncol Biol Phys 31 (1995) 725-734
20. van Lancker M., and Storme G. Prediction of severe late complications in fractionated, high dose-rate brachytherapy in gynecological applications. Int J Radiat Oncol Biol Phys 20 (1991) 1125-1129
21. Crook J.M., Esche B.A., Chaplain G., et al. Dose-volume analysis and the prevention of radiation sequelae in cervical cancer. Radiother Oncol 8 (1987) 321-332
22. Toita T., Kakinohana Y., Ogawa K., et al. Combination external beam radiotherapy and high-dose-rate intracavitary brachytherapy for uterine cervical cancer: Analysis of dose and fractionation schedule. Int J Radiat Oncol Biol Phys 56 (2003) 1344-1353
23. Kim T.H., Chol J., Park S.Y., et al. Dosimetric parameters that predict late rectal complications after curative radiotherapy in patients with uterine cervical carcinoma. Cancer 104 (2005) 1304-1311
24. Chun M., Kang S., Kil H.J., et al. Rectal bleeding and its management after irradiation for uterine cervical cancer. Int J Radiat Oncol Biol Phys 58 (2004) 98-105
25. Clark B.G., Souhami L., Roman T.N., et al. The prediction of late rectal complications in patients treated with high dose-rate brachytherapy for carcinoma of the cervix. Int J Radiat Oncol Biol Phys 38 (1997) 989-993
26. Wong F.C.S., Tung S.Y., Leung T.W., et al. Treatment results of high-dose-rate remote afterloading brachytherapy for cervical cancer and retrospective comparison of two regimens. Int J Radiat Oncol Biol Phys 55 (2003) 1254-1264
27. Cheng J.C.H., Peng L.C., Chen Y.H., et al. Unique role of proximal rectal dose in late rectal complications for patients with cervical cancer undergoing high-dose-rate intracavitary brachytherapy. Int J Radiat Oncol Biol Phys 57 (2003) 1010-1018
28. Hellebust T.P., Dale E., Skjonsberg A., et al. Interfraction variations in rectum and bladder volumes and dose distributions during high dose rate brachytherapy treatment of the uterine cervix investigated by repetitive CT-examinations. Radiother Oncol 60 (2001) 273-280
29. Heie-Meder C., Pötter R., van Limbergen E., et al. Recommendations from the Gynaecological (GYN) GEC ESTRO Working Group (I): Concepts and terms in 3D image based 3D treatment planning in cervix cancer brachytherapy with emphasis on MRI assessment of GTV and CTV. Radiother Oncol 74 (2005) 235-245
30. Pötter R., Heie-Meder C., van Limbergen E., et al. Recommendations from the Gynaecological (GYN) GEC ESTRO Working Group (II): Concepts and terms in 3D image-based treatment planning in cervix cancer brachytherapy-3D volume parameters and aspects of 3D image-based anatomy, radiation physics, radiobiology. Radiother Oncol 78 (2006) 67-77
31. Nag S., Cardenes H., Chang S., et al. Proposed guidelines for image-based intracavitary brachytherapy for cervical carcinoma: report from image-guided brachytherapy working group. Int J Radiat Oncol Biol Phys 60 (2004) 1160-1172
32. Koom W.S., Sohn D.K., Kim J.Y., et al. Computed tomography-based high-dose-rate intracavitary brachytherapy for uterine cervical cancer: Preliminary demonstration of correlation between dose-volume parameters and rectal mucosal changes observed by flexible sigmoidoscopy. Int J Radiat Oncol Biol Phys 68 (2007) 1446-1454
33. Hall E.J. Radiology for the radiologist. 5th ed. (2000), Lippincott Williams & Wilkins, Philadelphia