Hypohidrosis-related symptoms in pediatric epileptic patients with topiramate

Pediatrics International

Volumn 52, Issue 1, 2010, Pages 109-112

  Kim, Soon Chul ^a   Seol, In Joon ^b   Kim, Sun Jun ^a  

^a Chonbuk National University Medical School   (South Korea)

^b Hanyang University   (South Korea)

Author keywords

Aquaporin 5; Carbonic anhydrase; Hypohidrosis; Topiramate

Indexed keywords

TOPIRAMATE;

ANHIDROSIS; ARTICLE; BENIGN CHILDHOOD EPILEPSY; CHILD; CLINICAL ASSESSMENT; CONTROLLED STUDY; FEMALE; FLUSHING; HEAT INTOLERANCE; HEAT SENSATION; HUMAN; HYPERTHERMIA; INCIDENCE; IRRITABILITY; LETHARGY; MAJOR CLINICAL STUDY; MALE; MONOTHERAPY; PRESCHOOL CHILD; PRIORITY JOURNAL; PROSPECTIVE STUDY; PRURITUS; SCHOOL CHILD; SIDE EFFECT; TREATMENT DURATION;

ADOLESCENT; ANTICONVULSANTS; CHILD; CHILD, PRESCHOOL; CROSS-SECTIONAL STUDIES; DRUG THERAPY, COMBINATION; EPILEPSIES, PARTIAL; EPILEPSY, GENERALIZED; FEMALE; FRUCTOSE; HUMANS; HYPOHIDROSIS; INFANT; MALE; PROSPECTIVE STUDIES;

EID: 76249125935     PISSN: 13288067     EISSN: 1442200X     Source Type: Journal    
DOI: 10.1111/j.1442-200X.2009.02912.x     Document Type: Article

References (24)

1. LaRoche SM, Helmers SL. The new antiepileptic drugs. JAMA 2004 291: 605 620.
2. Winner P, Gendolla A, Stayer C et al. Topiramate for migraine prevention in adolescents: A pooled analysis of efficacy and safety. Headache 2006 46: 1503 1510.
3. Nieto-Barrera M, Nieto-Jimenez M, Candau R, Ruiz del Portal L Anhidrosis and hyperthermia associated with treatment with topiramate Rev. Neurol. 2002 34: 114 6 (in Spanish).
4. Sanchez Calso A, Anton Sanz MC Low sweat secretion due to topiramate Aten. Primaria 2002 30: 257 8 (in Spanish).
5. Arcas J, Ferrer T, Roche MC, Martinez-Bermejo A, Lopez-Martin V. Hypohidrosis related to the administration of topiramate to children. Epilepsia 2001 42: 1363 1365.
6. Shechter T, Shorer Z, Kramer U, Lerman-Saqie T, Ronen E, Rotem R, Gorodischer R. Adverse reactions of Topiramate and Lamotrigine in children. Pharmacoepidemiol. Drug Saf. 2005 14: 187 192.
7. Sato K, Kang WH, Saga K, Sato KT. Biology of sweat glands and their disorders, I: Normal sweat gland function. J. Am. Acad. Dermatol. 1989 20: 537 563. (Pubitemid 19091250)
8. Ferrer T, Ramos MJ, Perez-Sales P, Perez-Jimenez A, Alvarez E. Sympathetic sudomotor function and aging. Muscle Nerve 1995 18: 395 401.
9. Topamax. Topamax product information. Raritan, NJ: Ortho-McNeil Pharmaceutical, 2003.
10. Takeoka M, Holmes GL, Thiele E et al. Topiramate and metabolic acidosis in pediatric epilepsy. Epilepsia 2001 42: 387 392.
11. Otani K, Yanagihara K, Imai K, Futagi Y, Suzuki Y, Nagai T. Zonisamide and oligohidrosis. No To Hattatsu 1995 27 (Suppl. S127 (in Japanese).
12. Okumura A, Hayakawa F, Kuno K, Watanabe K. Oligohidrosis caused by zonisamide. No To Hattatsu 1996 28: 44 7 (in Japanese).
13. Okumura A, Ishihara N, Kato T, Hayakawa F, Kuno K, Watanabe K. Predictive value of acetylcholine stimulation testing for oligohidrosis caused by zonisamide. Pediatr. Neurol. 2000 23: 59 61.
14. Bundy HF. Carbonic anhydrase. Comp. Biochem. Physiol. 1977 57: 1 7.
15. Carter MJ. Carbonic anhydrase: Isoenzymes, properties, distribution, and functional significance. Biol. Rev. 1972 47: 465 513.
16. Dodgson SJ, Shank RP, Maryanoff BF. Topiramate as an inhibitor of carbonic anhydrase isoenzymes. Epilepsia 2000 41: 35 9.
17. Briggman JV, Tashian RE, Spicer SS. Immunohistochemical localization of carbonic anhydrase I and II in eccrine sweat glands from control subjects and patients with cystic fibrosis. Am. J. Pathol. 1983 112: 250 257.
18. Ben-Zeev B, Watemberg N, Augarten A et al. Oligohydrosis and hyperthermia: Pilot study of a novel Topiramate adverse effect. J. Child Neurol. 2003 18: 254 257.
19. Ma L, Huang Y-G, Deng Y-C et al. Topiramate reduced sweat secretion and aquaporin-5 expression in sweat glands of mice. Life Sci. 2007 80: 2461 2468.
20. Sato KT, Richardson A, Timm DE, Sato K. One-step iodine starch method for direct visualization of sweating. Am. J. Med. Sci. 1988 295: 528 531.
21. Sato KT. The mechanism of eccrine sweat secretion. In: Gisolfi CV, Lamb DR, Nadel ER ed). Perspectives in Exercise Science and Sports Medicine: Exercise, Heat, and Thermoregulation. Cooper Publishing Group, Caramel, IN, 1993 6: 85 117.
22. Juhlin L, Shelley WB. A stain for sweat pores. Nature 1967 213 408.
23. Gutrecht JA. Sympathetic skin response. J. Clin. Neurophysiol. 1994 11: 519 524.
24. Lee H, Lee SH, Kim SJ. Predictive value of indicator test for hypohidrosis with topiramate. Korean J. Pedatr. 2006 49: 1180 1185.