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Volumn 44, Issue 12, 2009, Pages 1328-1335

Advances in the study of tumor pH-responsive polymeric micelles for cancer drug targeting delivery

Author keywords

Chemotherapy; Drug delivery system; Micelle; Nanomedicine; Neoplasm; pH responsive; Polymer

Indexed keywords

ACRYLIC ACID DERIVATIVE; BETA AMINO ACID; DOXORUBICIN; MACROGOL; METHACRYLIC ACID METHYL ESTER; NANOPARTICLE; PACLITAXEL; POLY(2 VINYLPYRIDINE); POLY(4 VINYLPYRIDINE); POLY(N,N DIETHYLAMINOMETHYLMETHACRYLATE); POLYCAPROLACTONE; POLYETHYLENEIMINE; POLYHISTIDINE; POLYMER; UNCLASSIFIED DRUG;

EID: 76249121949     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (22)

References (53)
  • 1
    • 76249095942 scopus 로고    scopus 로고
    • Anti-cancer stratigies of WHO [J]. China
    • Yu SZ. Anti-cancer stratigies of WHO [J]. China Cancer 2009, 18: 88-99.
    • (2009) Cancer , vol.18 , pp. 88-99
    • Yu, S.Z.1
  • 2
    • 0028034467 scopus 로고
    • Cisplatin-induced renal toxicity and toxicity-modulating strategies: A review [J]
    • Pinzani V, Bressolle F, Hang IJ, et al. Cisplatin-induced renal toxicity and toxicity-modulating strategies: a review [J]. Cancer Chemother Pharmacol, 1994, 35: 1-9.
    • (1994) Cancer Chemother Pharmacol , vol.35 , pp. 1-9
    • Pinzani, V.1    Bressolle, F.2    Hang, I.J.3
  • 3
    • 0036176510 scopus 로고    scopus 로고
    • Mechanisms of cancer drug resistance [J]
    • Gottesman MM. Mechanisms of cancer drug resistance [J]. Annu Rev Med, 2002, 53: 615-627.
    • (2002) Annu Rev Med , vol.53 , pp. 615-627
    • Gottesman, M.M.1
  • 4
    • 65549161510 scopus 로고    scopus 로고
    • Current state and future applications of active targeting in malignancies using superparamagnetic iron oxide nanoparticles [J]
    • Islam T, Josephson L. Current state and future applications of active targeting in malignancies using superparamagnetic iron oxide nanoparticles [J]. Cancer Biomark, 2009, 5: 99-107.
    • (2009) Cancer Biomark , vol.5 , pp. 99-107
    • Islam, T.1    Josephson, L.2
  • 5
    • 55049139368 scopus 로고    scopus 로고
    • Advances in the study of small peptides in targeted drug delivery system [J]
    • Sun Y, Wang C. Advances in the study of small peptides in targeted drug delivery system [J]. Acta Pharm Sin 2008, 43: 992-996.
    • (2008) Acta Pharm Sin , vol.43 , pp. 992-996
    • Sun, Y.1    Wang, C.2
  • 6
    • 66149116471 scopus 로고    scopus 로고
    • Das M, Mohanty C, Sahoo SK. Ligand-based targeted therapy for cancer tissue [J]. Expert Opin Drug Deliv, 2009, 6: 285-304.
    • Das M, Mohanty C, Sahoo SK. Ligand-based targeted therapy for cancer tissue [J]. Expert Opin Drug Deliv, 2009, 6: 285-304.
  • 7
    • 1642541103 scopus 로고    scopus 로고
    • Polymeric micelles for delivery of poorly water-soluble compounds [J]
    • Kwon GS. Polymeric micelles for delivery of poorly water-soluble compounds [J]. Crit Rev Ther Drug Carrier Syst, 2003, 20: 357-403.
    • (2003) Crit Rev Ther Drug Carrier Syst , vol.20 , pp. 357-403
    • Kwon, G.S.1
  • 8
    • 0035937592 scopus 로고    scopus 로고
    • Block copolymer micelles for drug delivery: Design, characterization and biological significance [J]
    • Kataoka K, Harada A, Nagasaki Y. Block copolymer micelles for drug delivery: design, characterization and biological significance [J]. Adv Drug Deliv Rev, 2001, 47: 113-131.
    • (2001) Adv Drug Deliv Rev , vol.47 , pp. 113-131
    • Kataoka, K.1    Harada, A.2    Nagasaki, Y.3
  • 9
    • 0034996764 scopus 로고    scopus 로고
    • Longcirculating and target-specific nanoparticles: Theory to practice [J]
    • Moghimi SM, Hunter AC, Murray JC. Longcirculating and target-specific nanoparticles: theory to practice [J]. Pharmacol Rev, 2001, 53: 283-318.
    • (2001) Pharmacol Rev , vol.53 , pp. 283-318
    • Moghimi, S.M.1    Hunter, A.C.2    Murray, J.C.3
  • 10
    • 34249023676 scopus 로고    scopus 로고
    • Functionalized micellar systems for cancer targeted drug delivery [J]
    • Sutton D, Nasongkla N, Blanco E, et al. Functionalized micellar systems for cancer targeted drug delivery [J]. Pharm Res, 2007, 24:1029-1046.
    • (2007) Pharm Res , vol.24 , pp. 1029-1046
    • Sutton, D.1    Nasongkla, N.2    Blanco, E.3
  • 11
    • 54249090665 scopus 로고    scopus 로고
    • Magnetic and pH-responsive nanocarriers with multilayer core-shell architecture for anti-cancer drug delivery [J]
    • Guo M, Yan Y, Zhang HK, et al. Magnetic and pH-responsive nanocarriers with multilayer core-shell architecture for anti-cancer drug delivery [J]. J Mater Chem, 2008, 18: 5104-5112.
    • (2008) J Mater Chem , vol.18 , pp. 5104-5112
    • Guo, M.1    Yan, Y.2    Zhang, H.K.3
  • 12
    • 38049049703 scopus 로고    scopus 로고
    • Folate-conjugated polymer micelles for active targeting to cancer cells: Preparation, in vitro evaluation of targeting ability and cytotoxicity [J]
    • You J, Li X, Cui FD, et al. Folate-conjugated polymer micelles for active targeting to cancer cells: preparation, in vitro evaluation of targeting ability and cytotoxicity [J]. Nanotechnology, 2008, 19, 045102.
    • (2008) Nanotechnology , vol.19 , pp. 045102
    • You, J.1    Li, X.2    Cui, F.D.3
  • 13
    • 34547561267 scopus 로고    scopus 로고
    • Physical stimuli-responsive polymeric micelles for anti-cancer drug delivery [J]
    • Rapoport N. Physical stimuli-responsive polymeric micelles for anti-cancer drug delivery [J]. Prog Polym Sci, 2007, 32: 962-990.
    • (2007) Prog Polym Sci , vol.32 , pp. 962-990
    • Rapoport, N.1
  • 14
    • 56949105019 scopus 로고    scopus 로고
    • Recent progress in tumor pH targeting nanotechnology [J]
    • Lee ES, Gao ZG, Bae YH. Recent progress in tumor pH targeting nanotechnology [J]. J Control Release, 2008, 132: 164-170.
    • (2008) J Control Release , vol.132 , pp. 164-170
    • Lee, E.S.1    Gao, Z.G.2    Bae, Y.H.3
  • 15
    • 0033986761 scopus 로고    scopus 로고
    • Causes and consequences of tumor acidity and implications for treatment [J]
    • Stubbs M, McSheehy PMJ, Griffiths JR, et al. Causes and consequences of tumor acidity and implications for treatment [J]. Mol Med Today, 2000, 6: 15-19.
    • (2000) Mol Med Today , vol.6 , pp. 15-19
    • Stubbs, M.1    McSheehy, P.M.J.2    Griffiths, J.R.3
  • 16
    • 0028072842 scopus 로고
    • Noninvasive measurement of interstital pH profiles in normal and neoplastic tissue using fluorescence ratio imaging microscopy [J]
    • Martin GR, Jain RK. Noninvasive measurement of interstital pH profiles in normal and neoplastic tissue using fluorescence ratio imaging microscopy [J]. Cancer Res, 1994, 54: 5670-5674.
    • (1994) Cancer Res , vol.54 , pp. 5670-5674
    • Martin, G.R.1    Jain, R.K.2
  • 17
    • 0021281777 scopus 로고
    • Endosome pH measured in single cells by dual fluorescence flow cytometry: Rapid acidification of insulin to pH 6 [J]
    • Murphy RF, Powers S, Cantor CR. Endosome pH measured in single cells by dual fluorescence flow cytometry: rapid acidification of insulin to pH 6 [J]. J Cell Biol, 1984, 98: 1757-1762.
    • (1984) J Cell Biol , vol.98 , pp. 1757-1762
    • Murphy, R.F.1    Powers, S.2    Cantor, C.R.3
  • 18
    • 0026802406 scopus 로고
    • Characterization of early and late endocytic compartments of the transferrin cycle: Transferrin receptor antibody blocks erythroid differentiation by trapping the receptor in the early endosome [J]
    • Killisch I, Steinlein P, Romisch K, et al. Characterization of early and late endocytic compartments of the transferrin cycle: transferrin receptor antibody blocks erythroid differentiation by trapping the receptor in the early endosome [J]. J Cell Sci, 1992, 103: 211-232.
    • (1992) J Cell Sci , vol.103 , pp. 211-232
    • Killisch, I.1    Steinlein, P.2    Romisch, K.3
  • 19
    • 0024564284 scopus 로고
    • Acidification of endosome subpopulations in wild-type Chinese hamster ovary cells and temperature- sensitive acidification-defective mutants [J]
    • Schmid S, Fuchs R, Kielian M, et al. Acidification of endosome subpopulations in wild-type Chinese hamster ovary cells and temperature- sensitive acidification-defective mutants [J]. J Cell Biol, 1989, 108: 1291-1300.
    • (1989) J Cell Biol , vol.108 , pp. 1291-1300
    • Schmid, S.1    Fuchs, R.2    Kielian, M.3
  • 20
    • 0020674618 scopus 로고
    • Endocytosis and the recycling of plasma membrane [J]
    • Steinman RM, Mellman IS, Muller WA, et al. Endocytosis and the recycling of plasma membrane [J]. J Cell Biol, 1983, 96: 1-27.
    • (1983) J Cell Biol , vol.96 , pp. 1-27
    • Steinman, R.M.1    Mellman, I.S.2    Muller, W.A.3
  • 21
    • 57749194622 scopus 로고    scopus 로고
    • Enhanced core hydrophobicity, functionalization and cell penetration of polybasic nanomatrices [J]
    • Fisher OZ, Kim Timothy, Dietz SR, et al. Enhanced core hydrophobicity, functionalization and cell penetration of polybasic nanomatrices [J]. Pharm Res, 2009, 26: 51-60.
    • (2009) Pharm Res , vol.26 , pp. 51-60
    • Fisher, O.Z.1    Kim Timothy, D.S.R.2
  • 22
    • 26444538049 scopus 로고    scopus 로고
    • Core-shell particles having silica cores and pH-responsive poly(vinylpyridine) shells [J]
    • Atkin R, Bradley M, Vincent B. Core-shell particles having silica cores and pH-responsive poly(vinylpyridine) shells [J]. Soft Matter, 2005, 1: 160-165.
    • (2005) Soft Matter , vol.1 , pp. 160-165
    • Atkin, R.1    Bradley, M.2    Vincent, B.3
  • 23
    • 64149119603 scopus 로고    scopus 로고
    • Cancer-associated pH-responsive tetracopolymeric micelles composed of poly(ethylene glycol)-b-poly (L-histidine)-b-poly( L-lactic acid)-b-poly(ethylene glycol) [J]
    • Oh KT, Lee ES. Cancer-associated pH-responsive tetracopolymeric micelles composed of poly(ethylene glycol)-b-poly (L-histidine)-b-poly( L-lactic acid)-b-poly(ethylene glycol) [J]. Polym Adv Technol, 2008, 19: 1907-1913.
    • (2008) Polym Adv Technol , vol.19 , pp. 1907-1913
    • Oh, K.T.1    Lee, E.S.2
  • 24
    • 67349140207 scopus 로고    scopus 로고
    • Degradable poly (β-amino ester) nanoparticles for cancer cytoplasmic drug delivery [J]
    • Shen YQ, Tang HD, Zhan YH, et al. Degradable poly (β-amino ester) nanoparticles for cancer cytoplasmic drug delivery [J]. Nanomedicine, 2009, 5: 192-201.
    • (2009) Nanomedicine , vol.5 , pp. 192-201
    • Shen, Y.Q.1    Tang, H.D.2    Zhan, Y.H.3
  • 25
    • 34547174656 scopus 로고    scopus 로고
    • Interaction between methylene blue and cyclic methacrylic acid oligomer [J]
    • Saito R, Yamaguchi K, Hara T, et al. Interaction between methylene blue and cyclic methacrylic acid oligomer [J]. Macromolecules, 2007, 40: 4621-4625.
    • (2007) Macromolecules , vol.40 , pp. 4621-4625
    • Saito, R.1    Yamaguchi, K.2    Hara, T.3
  • 26
    • 35348955398 scopus 로고    scopus 로고
    • Thermo and pH dual-responsive nanoparticles for anti-cancer drug delivery [J]
    • Zhang L, Guo R, Yang M, et al. Thermo and pH dual-responsive nanoparticles for anti-cancer drug delivery [J]. Adv Mater, 2007, 19: 2988-2992.
    • (2007) Adv Mater , vol.19 , pp. 2988-2992
    • Zhang, L.1    Guo, R.2    Yang, M.3
  • 27
    • 0041834834 scopus 로고    scopus 로고
    • Evaluation of pH-dependent membrane-disruptive properties of poly(acrylic acid) derived polymers [J]
    • Kusonwiriyawong C, van de Wetering P, Hubbell JA, et al. Evaluation of pH-dependent membrane-disruptive properties of poly(acrylic acid) derived polymers [J]. Eur J Pharm Biopharm, 2003, 56: 237-246.
    • (2003) Eur J Pharm Biopharm , vol.56 , pp. 237-246
    • Kusonwiriyawong, C.1    van de Wetering, P.2    Hubbell, J.A.3
  • 28
    • 42149142911 scopus 로고    scopus 로고
    • Progress in the study of pH and temperature sensitive biodegradable block copolymers [J]
    • Hao TN, Qiao MX, Li Z, et al. Progress in the study of pH and temperature sensitive biodegradable block copolymers [J]. Acta Pharm Sin 2008, 43: 123-127.
    • (2008) Acta Pharm Sin , vol.43 , pp. 123-127
    • Hao, T.N.1    Qiao, M.X.2    Li, Z.3
  • 29
    • 0142119372 scopus 로고    scopus 로고
    • Design of environment-sensitive supramolecular assemblies for intracellular drug delivery: Polymeric micelles that are responsive to intracellular pH change [J]
    • Bae Y, Fukushima S, Harada A, et al. Design of environment-sensitive supramolecular assemblies for intracellular drug delivery: polymeric micelles that are responsive to intracellular pH change [J]. Angew Chem Int Ed, 2003, 42: 4640-4643.
    • (2003) Angew Chem Int Ed , vol.42 , pp. 4640-4643
    • Bae, Y.1    Fukushima, S.2    Harada, A.3
  • 30
    • 12344269847 scopus 로고    scopus 로고
    • Preparation and biological characterization of polymeric micelle drug carriers with intracellular pH-triggered drug release property: Tumor permeability, controlled subcellular drug distribution, and enhanced in vivo antitumor efficacy [J]
    • Bae Y, Nishiyama N, Fukushima S, et al. Preparation and biological characterization of polymeric micelle drug carriers with intracellular pH-triggered drug release property: tumor permeability, controlled subcellular drug distribution, and enhanced in vivo antitumor efficacy [J]. Bioconjugate Chem, 2005, 16: 122-130.
    • (2005) Bioconjugate Chem , vol.16 , pp. 122-130
    • Bae, Y.1    Nishiyama, N.2    Fukushima, S.3
  • 31
    • 15244345124 scopus 로고    scopus 로고
    • pH-responsive copolymer assemblies for controlled release of doxorubicin [J]
    • Gillies ER, Frechet JMJ. pH-responsive copolymer assemblies for controlled release of doxorubicin [J]. Bioconjugate Chem, 2005, 16: 361-368.
    • (2005) Bioconjugate Chem , vol.16 , pp. 361-368
    • Gillies, E.R.1    Frechet, J.M.J.2
  • 32
    • 4644264045 scopus 로고    scopus 로고
    • Stimuli-responsive supramolecular assemblies of linear-dendritic copolymers [J]
    • Gillies ER, Jonsson TB, Frechet JMJ. Stimuli-responsive supramolecular assemblies of linear-dendritic copolymers [J]. J Am Chem Soc, 2004, 126: 11936-11943.
    • (2004) J Am Chem Soc , vol.126 , pp. 11936-11943
    • Gillies, E.R.1    Jonsson, T.B.2    Frechet, J.M.J.3
  • 33
    • 34447298630 scopus 로고    scopus 로고
    • Targeted charge reversal nanoparticles for nuclear drug delivery [J]
    • Xu PS, Van Kirk EA, Zhan YH, et al. Targeted charge reversal nanoparticles for nuclear drug delivery [J]. Angew Chem (Int Ed Engl), 2007, 46: 4999-5002.
    • (2007) Angew Chem (Int Ed Engl) , vol.46 , pp. 4999-5002
    • Xu, P.S.1    Van Kirk, E.A.2    Zhan, Y.H.3
  • 34
    • 61849097305 scopus 로고    scopus 로고
    • Acid-sensitive polymeric micelles based on thermoresponsive block copolymers with pendent cyclic orthoester groups [J]
    • Huang XN, Du FS, Cheng J, et al. Acid-sensitive polymeric micelles based on thermoresponsive block copolymers with pendent cyclic orthoester groups [J]. Macromolecules, 2009, 42: 783-790.
    • (2009) Macromolecules , vol.42 , pp. 783-790
    • Huang1    XN, D.F.2    Cheng, J.3
  • 35
    • 0038106270 scopus 로고    scopus 로고
    • Poly(L-histidine)-PEG block copolymer micelles and pH-induced destabilization targeted charge reversal nanoparticles for nuclear drug delivery [J]
    • Lee ES, Shin HJ, Na K, et al. Poly(L-histidine)-PEG block copolymer micelles and pH-induced destabilization targeted charge reversal nanoparticles for nuclear drug delivery [J]. J Control Release, 2003, 90: 363-374.
    • (2003) J Control Release , vol.90 , pp. 363-374
    • Lee, E.S.1    Shin, H.J.2    Na, K.3
  • 36
    • 0141921483 scopus 로고    scopus 로고
    • Polymeric micelle for tumor pH and folate-mediated targeting [J]
    • Lee ES, Na K, Bae YH. Polymeric micelle for tumor pH and folate-mediated targeting [J]. J Control Release, 2003, 91: 103-113.
    • (2003) J Control Release , vol.91 , pp. 103-113
    • Lee, E.S.1    Na, K.2    Bae, Y.H.3
  • 37
    • 30644478967 scopus 로고    scopus 로고
    • Doxorubicin loaded pH-sensitive micelle targeting acidic extracellular pH of human ovarian A2780 tumor in mice [J]
    • Gao ZG, Lee DH, Kim DI, et al. Doxorubicin loaded pH-sensitive micelle targeting acidic extracellular pH of human ovarian A2780 tumor in mice [J]. J Drug Target, 2005, 13: 391-397.
    • (2005) J Drug Target , vol.13 , pp. 391-397
    • Gao, Z.G.1    Lee, D.H.2    Kim, D.I.3
  • 38
    • 35248821266 scopus 로고    scopus 로고
    • Tumoral acidic extracellular pH targeting of pH-responsive MPEG-poly([beta]-amino ester) block copolymer micelles for cancer therapy [J]
    • Ko J, Park K, Kim YS, et al. Tumoral acidic extracellular pH targeting of pH-responsive MPEG-poly([beta]-amino ester) block copolymer micelles for cancer therapy [J]. J Control Release, 2007, 123: 109-115.
    • (2007) J Control Release , vol.123 , pp. 109-115
    • Ko, J.1    Park, K.2    Kim, Y.S.3
  • 39
    • 14644433029 scopus 로고    scopus 로고
    • Super pH-sensitive multifunctional polymeric micelle [J]
    • Lee ES, Na K, Bae YH. Super pH-sensitive multifunctional polymeric micelle [J]. Nano Lett, 2005, 5: 325-329.
    • (2005) Nano Lett , vol.5 , pp. 325-329
    • Lee, E.S.1    Na, K.2    Bae, Y.H.3
  • 40
    • 47349097049 scopus 로고    scopus 로고
    • Super pH-sensitive multi-functional polymeric micelle for tumor pHe specific TAT exposure and multidrug resistance [J]
    • Lee ES, Gao ZG, Kim D, et al. Super pH-sensitive multi-functional polymeric micelle for tumor pHe specific TAT exposure and multidrug resistance [J]. J Control Release, 2008, 129: 228-236.
    • (2008) J Control Release , vol.129 , pp. 228-236
    • Lee, E.S.1    Gao, Z.G.2    Kim, D.3
  • 41
    • 55749102507 scopus 로고    scopus 로고
    • Multifunctioning pH-responsive nanoparticles from hierarchical self-assembly of polymer brush for cancer drug delivery [J]
    • Shen YQ, Zhan YH, Tang JB, et al. Multifunctioning pH-responsive nanoparticles from hierarchical self-assembly of polymer brush for cancer drug delivery [J]. AIChE J, 2008, 54: 2979-2989.
    • (2008) AIChE J , vol.54 , pp. 2979-2989
    • Shen, Y.Q.1    Zhan, Y.H.2    Tang, J.B.3
  • 42
    • 34548267667 scopus 로고    scopus 로고
    • Endocytic mechanisms for targeted drug delivery [J]
    • Bareford LM, Swaan PW. Endocytic mechanisms for targeted drug delivery [J]. Adv Drug Deliv Rev, 2007, 59: 748-758.
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 748-758
    • Bareford, L.M.1    Swaan, P.W.2
  • 43
    • 36249023813 scopus 로고    scopus 로고
    • Cytosolic delivery of membrane-impermeable molecules in dendritic cells using pH-responsive core-shell nanoparticles [J]
    • Hu Y, Litwin T, Nagaraja AR, et al. Cytosolic delivery of membrane-impermeable molecules in dendritic cells using pH-responsive core-shell nanoparticles [J]. Nano Lett, 2007, 7: 3056-3064.
    • (2007) Nano Lett , vol.7 , pp. 3056-3064
    • Hu, Y.1    Litwin, T.2    Nagaraja, A.R.3
  • 44
    • 14844303778 scopus 로고    scopus 로고
    • Doxorubicin loaded pH-sensitive polymeric micelles for reversal of resistant MCF-7 tumor [J]
    • Lee ES, Na K, Bae YH. Doxorubicin loaded pH-sensitive polymeric micelles for reversal of resistant MCF-7 tumor [J]. J Control Release, 2005, 103: 405-418.
    • (2005) J Control Release , vol.103 , pp. 405-418
    • Lee, E.S.1    Na, K.2    Bae, Y.H.3
  • 45
    • 49549098607 scopus 로고    scopus 로고
    • Doxorubicin Loaded pH-sensitive micelle: Antitumoral efficacy against ovarian A2780/DOXR tumor [J]
    • Kim D, Lee ES, Park K, et al. Doxorubicin Loaded pH-sensitive micelle: antitumoral efficacy against ovarian A2780/DOXR tumor [J]. Pharma Res, 2008, 25: 2074-2082.
    • (2008) Pharma Res , vol.25 , pp. 2074-2082
    • Kim, D.1    Lee, E.S.2    Park, K.3
  • 46
    • 33645529852 scopus 로고    scopus 로고
    • Anticancer efficacies of cisplatin-releasing pH-responsive nanoparticles [J]
    • Xu PS, Van Kirk EA, Murdoch WJ, et al. Anticancer efficacies of cisplatin-releasing pH-responsive nanoparticles [J]. Biomacromolecules, 2006, 7: 829-835.
    • (2006) Biomacromolecules , vol.7 , pp. 829-835
    • Xu, P.S.1    Van Kirk, E.A.2    Murdoch, W.J.3
  • 47
    • 67749143922 scopus 로고    scopus 로고
    • Expansile nanoparticles: Synthesis, characterization, and in vivo efficacy of an acid-responsive polymeric drug delivery [J]
    • Griset AP, Walpole J, Liu R, et al. Expansile nanoparticles: synthesis, characterization, and in vivo efficacy of an acid-responsive polymeric drug delivery [J]. J Am Chem Soc, 2009, 131: 2469-2471.
    • (2009) J Am Chem Soc , vol.131 , pp. 2469-2471
    • Griset, A.P.1    Walpole, J.2    Liu, R.3
  • 48
    • 84876035013 scopus 로고    scopus 로고
    • Fuertes MA, Castilla J, Alonso C, et al. Molecular pharmacology of cisplatin: from cellular damage to apoptosis induction [J]. Recent Res Develop Mol Pharmacol, 2002, 1: 37-51.
    • Fuertes MA, Castilla J, Alonso C, et al. Molecular pharmacology of cisplatin: from cellular damage to apoptosis induction [J]. Recent Res Develop Mol Pharmacol, 2002, 1: 37-51.
  • 49
    • 0030786591 scopus 로고    scopus 로고
    • Anthracycline subcellular distribution in human leukemic cells by microspectrofluorometry: Factors contributing to drug-induced cell death and reversal of multidrug resistance [J]
    • Morjani H, Millot JM, Belhoussine R, et al. Anthracycline subcellular distribution in human leukemic cells by microspectrofluorometry: factors contributing to drug-induced cell death and reversal of multidrug resistance [J]. Leakemia, 1997, 11: 1170-1179.
    • (1997) Leakemia , vol.11 , pp. 1170-1179
    • Morjani, H.1    Millot, J.M.2    Belhoussine, R.3
  • 50
    • 3843092828 scopus 로고    scopus 로고
    • Chances and pitfalls of cell penetrating peptides for cellular drug delivery [J]
    • Trehin R, Merkle HP. Chances and pitfalls of cell penetrating peptides for cellular drug delivery [J]. Eur J Pharm Biopharm, 2004, 58: 209-223.
    • (2004) Eur J Pharm Biopharm , vol.58 , pp. 209-223
    • Trehin, R.1    Merkle, H.P.2
  • 51
    • 33847671358 scopus 로고    scopus 로고
    • TAT peptide-based micelle system for potential active targeting of anti-cancer agents to acidic solid tumors [J]
    • Sethuraman VA, Bae YH. TAT peptide-based micelle system for potential active targeting of anti-cancer agents to acidic solid tumors [J]. J Control Release, 2007, 118: 216-224.
    • (2007) J Control Release , vol.118 , pp. 216-224
    • Sethuraman, V.A.1    Bae, Y.H.2
  • 52
    • 0033609001 scopus 로고    scopus 로고
    • Tracking the intracellular path of poly(ethylenimine)/DNA complexes for gene delivery [J]
    • Godbey WT, Wu KK, Mikos AG. Tracking the intracellular path of poly(ethylenimine)/DNA complexes for gene delivery [J]. Proc Natl Acad Sci USA, 1999, 96: 5177-5181.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 5177-5181
    • Godbey, W.T.1    Wu, K.K.2    Mikos, A.G.3
  • 53
    • 0035910871 scopus 로고    scopus 로고
    • The fate of poly (2-dimethylaminoethyl methacrylate)-based polyplexes after intravenous administration [J]
    • Verbaan FJ, Oussoren C, van Dam IM, et al. The fate of poly (2-dimethylaminoethyl methacrylate)-based polyplexes after intravenous administration [J]. Int J Pharm, 2001, 214: 99-101.
    • (2001) Int J Pharm , vol.214 , pp. 99-101
    • Verbaan, F.J.1    Oussoren, C.2    van Dam, I.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.