Cell density-dependent increase in the level of protease-resistant prion protein in prion-infected Neuro2a mouse euroblastoma cells

Journal of General Virology

Volumn 91, Issue 2, 2010, Pages 563-569

  Nakamitsu, Satoshi ^a   Kurokawa, Aya ^a   Yamasaki, Takeshi ^a   Uryu, Masahide ^a   Hasebe, Rie ^a   Horiuchi, Motohiro ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; PRION PROTEIN; PROTEINASE; PEPTIDE HYDROLASE;

ANIMAL CELL; ARTICLE; CELL CONTACT; CELL DENSITY; CONTROLLED STUDY; INFECTION SENSITIVITY; MOUSE; NERVE CELL CULTURE; NEUROBLASTOMA CELL; NONHUMAN; PRION DISEASE; PRIORITY JOURNAL; ANIMAL; CELL; CELL COUNT; CHEMISTRY; CYTOLOGY; METABOLISM; NEUROBLASTOMA; PRION; TUMOR CELL LINE;

ANIMALS; CELL COUNT; CELL LINE, TUMOR; CELLS; MICE; NEUROBLASTOMA; PEPTIDE HYDROLASES; PRIONS;

EID: 76249121802     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/vir.0.016287-0     Document Type: Article

References (30)

1. Sc accumulation in myocytes from sheep incubating natural scrapie. Nat Med 10, 591-593.
2. Bate, C., Langeveld, J. & Williams, A. (2004). Manipulation of PrPres production in scrapie-infected neuroblastoma cells. J Neurosci Methods 138, 217-223.
3. Borchelt, D. R., Taraboulos, A. & Prusiner, S. B. (1992). Evidence for synthesis of scrapie prion proteins in the endocytic pathway. J Biol Chem 267, 16188-16199.
4. Cansell, M., Gouygou, J. P., Jozefonvicz, J. & Letourneur, D. (1997). Lipid composition of cultured endothelial cells in relation to their growth. Lipids 32, 39-44.
5. Caughey, B. & Raymond, G. J. (1991). The scrapie-associated form of PrP is made from a cell surface precursor that is both protease- and phospholipase-sensitive. J Biol Chem 266, 18217-18223.
6. Christian, A. E., Haynes, M. P., Phillips, M. C. & Rothblat, G. H. (1997). Use of cyclodextrins for manipulating cellular cholesterol content. J Lipid Res 38, 2264-2272.
7. Corvera, S., DiBonaventura, C. & Shpetner, H. S. (2000). Cell confluence-dependent remodeling of endothelial membranes mediated by cholesterol. J Biol Chem 275, 31414-31421.
8. Fevrier, B., Vilette, D., Archer, F., Loew, D., Faigle, W., Vidal, M., Laude, H. & Raposo, G. (2004). Cells release prions in association with exosomes. Proc Natl Acad Sci U S A 101, 9683-9688.
9. Ghaemmaghami, S., Phuan, P., Perkins, B., Ullman, J., May, B. C. H., Cohen, F. E. & Prusiner, S. B. (2007). Cell division modulates prion accumulation in cultured cells. Proc Natl Acad Sci U S A 104, 17971-17976.
10. Gousset, K., Schiff, E., Langevin, C., Marijanovic, Z., Caputo, A., Browman, D. T., Chenouard, N., de Chaumont, F., Martino, A. & other authors (2009). Prions hijack tunnelling nanotubes for intercellular spread. Nat Cell Biol 11, 328-336.
11. Hagiwara, K., Nakamura, Y., Nishijima, M. & Yamakawa, Y. (2007). Prevention of prion propagation by dehydrocholesterol reductase inhibitors in cultured cells and a therapeutic trial in mice. Biol Pharm Bull 30, 835-838.
12. Kitamoto, T., Shin, R. W., Doh-ura, K., Tomokane, N., Miyazono, M., Muramoto, T. & Tateishi, J. (1992). Abnormal isoform of prion proteins accumulates in the synaptic structures of the central nervous system in patients with Creutzfeldt-Jakob disease. Am J Pathol 140, 1285-1294.
13. Klingenstein, R., Löber, S., Kujala, P., Godsave, S., Leliveld, S. R., Gmeiner, P., Peters, P. J. & Korth, C. (2006). Tricyclic antidepressants, quinacrine and a novel, synthetic chimera thereof clear prions by destabilizing detergent-resistant membrane compartments. J Neurochem 98, 748-759.
14. Liscum, L. & Underwood, K. W. (1995). Intracellular cholesterol transport and compartmentation. J Biol Chem 270, 15443-15446.
15. Marijanovic, Z., Caputo, A., Campana, V. & Zurzolo, C. (2009). Identification of an intracellular site of prion conversion. PLoS Pathog 5, e1000426.
16. Mattei, V., Barenco, M. G., Tasciotti, V., Garofalo, T., Longo, A., Boller, K., Löwer, J., Misasi, R., Montrasio, F. & Sorice, M. (2009). Paracrine diffusion of PrP(C) and propagation of prion infectivity by plasma membrane-derived microvesicles. PLoS One 4, e5057.
17. Naslavsky, N., Stein, R., Yanai, A., Friedlander, G. & Taraboulos, A. (1997). Characterization of detergent-insoluble complexes containing the cellular prion protein and its scrapie isoform. J Biol Chem 272, 6324-6331.
18. Sc fraction. Biochemistry 45, 15710-15717.
19. Prior, M., Lehmann, S., Sy, M., Molloy, B. & McMahon, H. E. M. (2007). Cyclodextrins inhibit replication of scrapie prion protein in cell culture. J Virol 81, 11195-11207.
20. Rubenstein, R., Scalici, C. L., Papini, M. C., Callahan, S. M. & Carp, R. I. (1990). Further characterization of scrapie replication in PC12 cells. J Gen Virol 71, 825-831.
21. Safar, J. G., Geschwind, M. D., Deering, C., Didorenko, S., Sattavat, M., Sanchez, H., Serban, A., Vey, M., Baron, H. & other authors (2005). Diagnosis of human prion disease. Proc Natl Acad Sci U S A 102, 3501-3506.
22. Simons, M., Keller, P., De Strooper, B., Beyreuther, K., Dotti, C. G. & Simons, K. (1998). Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons. Proc Natl Acad Sci U S A 95, 6460-6464.
23. Sparrow, S. M., Carter, J. M., Ridgway, N. D., Cook, H. W. & Byers, D. M. (1999). U18666A inhibits intracellular cholesterol transport and neurotransmitter release in human neuroblastoma cells. Neurochem Res 24, 69-77.
24. Takahashi, M., Murate, M., Fukuda, M., Sato, S. B., Ohta, A. & Kobayashi, T. (2007). Cholesterol controls lipid endocytosis through Rab11. Mol Biol Cell 18, 2667-2677.
25. Taraboulos, A., Scott, M., Semenov, A., Avrahami, D., Laszlo, L., Prusiner, S. B. & Avraham, D. (1995). Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform. J Cell Biol 129, 121-132.
26. Sc in muscles of hamsters orally exposed to scrapie. J Clin Invest 113, 1465-1472.
27. Tzaban, S., Friedlander, G., Schonberger, O., Horonchik, L., Yedidia, Y., Shaked, G., Gabizon, R. & Taraboulos, A. (2002). Protease-sensitive scrapie prion protein in aggregates of heterogeneous sizes. Biochemistry 41, 12868-12875.
28. Uryu, M., Karino, A., Kamihara, Y. & Horiuchi, M. (2007). Characterization of prion susceptibility in Neuro2a mouse neuroblastoma cell subclones. Microbiol Immunol 51, 661-669.
29. Vey, M., Pilkuhn, S., Wille, H., Nixon, R., DeArmond, S. J., Smart, E. J., Anderson, R. G., Taraboulos, A. & Prusiner, S. B. (1996). Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains. Proc Natl Acad Sci U S A 93, 14945-14949.
30. Weissmann, C. (2004). The state of the prion. Nat Rev Microbiol 2, 861-871.