메뉴 건너뛰기




Volumn 32, Issue 3, 2010, Pages 333-340

Expression of hedgehog signaling molecules in Merkel cell carcinoma

Author keywords

Indian hedgehog; Merkel cell carcinoma; Patched; Smoothened hedgehog; Sonic hedgehog

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; CYCLOPHOSPHAMIDE; DACARBAZINE; DIMETHOATE; DOXORUBICIN; ETOPOSIDE; METHOTREXATE; PROTEIN PATCHED; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR GLI2; TRANSCRIPTION FACTOR GLI3; VINCRISTINE;

EID: 76249117822     PISSN: 10433074     EISSN: 10970347     Source Type: Journal    
DOI: 10.1002/hed.21191     Document Type: Article
Times cited : (41)

References (25)
  • 1
    • 0033604515 scopus 로고    scopus 로고
    • Hedgehog signal transduction: From flies to vertebrates
    • Murone M, Rosenthal A, de Sauvage FJ. Hedgehog signal transduction: from flies to vertebrates. Exp Cell Res 1999;253:25-33.
    • (1999) Exp Cell Res , vol.253 , pp. 25-33
    • Murone, M.1    Rosenthal, A.2    de Sauvage, F.J.3
  • 3
    • 0242669237 scopus 로고    scopus 로고
    • Hedgehog signaling within airway epithelial progenitors and in small cell lung cancer
    • Watkins DN, Berman DM, Burkholder SG, et al. Hedgehog signaling within airway epithelial progenitors and in small cell lung cancer. Nature 2003;422:313-317.
    • (2003) Nature , vol.422 , pp. 313-317
    • Watkins, D.N.1    Berman, D.M.2    Burkholder, S.G.3
  • 4
    • 4143097168 scopus 로고    scopus 로고
    • Expression of Sonic hedgehog pathway genes is altered in colonic neoplasia
    • Oniscu A, James RM, Morris RG, et al. Expression of Sonic hedgehog pathway genes is altered in colonic neoplasia. J Pathol 2004;203:909-917.
    • (2004) J Pathol , vol.203 , pp. 909-917
    • Oniscu, A.1    James, R.M.2    Morris, R.G.3
  • 5
    • 33746319149 scopus 로고    scopus 로고
    • Enhanced expression of hedgehog signaling molecules in squamous cell carcinoma of uterine cervix and its precursor lesions
    • Xuan YH, Jung HS, Choi YL, et al. Enhanced expression of hedgehog signaling molecules in squamous cell carcinoma of uterine cervix and its precursor lesions. Mod Pathol 2006;19:1139-1147.
    • (2006) Mod Pathol , vol.19 , pp. 1139-1147
    • Xuan, Y.H.1    Jung, H.S.2    Choi, Y.L.3
  • 6
    • 4344586961 scopus 로고    scopus 로고
    • Hedgehog signaling pathway is a new therapeutic target for patients with breast cancer
    • Kubo M, Nakamura M, Tasaki A, et al. Hedgehog signaling pathway is a new therapeutic target for patients with breast cancer. Cancer Res 2004;64:6071-6074.
    • (2004) Cancer Res , vol.64 , pp. 6071-6074
    • Kubo, M.1    Nakamura, M.2    Tasaki, A.3
  • 7
    • 63949084660 scopus 로고    scopus 로고
    • Prevalence of Merkel cell polyomavirus in Merkel cell carcinoma
    • Feb 27, Epub ahead of print
    • Duncavage EJ, Zehnbauer BA, Pfeifer JD. Prevalence of Merkel cell polyomavirus in Merkel cell carcinoma. Mod Pathol 2009;Feb 27. [Epub ahead of print].
    • (2009) Mod Pathol
    • Duncavage, E.J.1    Zehnbauer, B.A.2    Pfeifer, J.D.3
  • 8
    • 37349072449 scopus 로고    scopus 로고
    • A comprehensive review of the treatment of Merkel cell carcinoma
    • Eng TY, Boersma MG, Fuller CD, et al. A comprehensive review of the treatment of Merkel cell carcinoma. Am J Clin Oncol 2007;30:624-636.
    • (2007) Am J Clin Oncol , vol.30 , pp. 624-636
    • Eng, T.Y.1    Boersma, M.G.2    Fuller, C.D.3
  • 10
    • 0031822837 scopus 로고    scopus 로고
    • Tissue microarrays for high-throughput molecular profiling of tumor specimens
    • Kononen J, Bubendorf L, Kallioniemi A, et al. Tissue microarrays for high-throughput molecular profiling of tumor specimens. Nat Med 1998;4:844-847.
    • (1998) Nat Med , vol.4 , pp. 844-847
    • Kononen, J.1    Bubendorf, L.2    Kallioniemi, A.3
  • 11
    • 0028896159 scopus 로고
    • bcl-2 and p53 oncoprotein expression during colorectal tumorigenesis
    • Sinicrope FA, Ruan SB, Cleary KR, et al. bcl-2 and p53 oncoprotein expression during colorectal tumorigenesis. Cancer Res 1995;55:237-241.
    • (1995) Cancer Res , vol.55 , pp. 237-241
    • Sinicrope, F.A.1    Ruan, S.B.2    Cleary, K.R.3
  • 12
    • 35349016886 scopus 로고    scopus 로고
    • TdT expression in Merkel cell carcinoma: Potential diagnostic pitfall with blastic hematological malignancies and expanded immunohistochemical analysis
    • Sur M, AlArdati H, Ross C, Alowami S. TdT expression in Merkel cell carcinoma: potential diagnostic pitfall with blastic hematological malignancies and expanded immunohistochemical analysis. Mod Pathol 2007;20: 1113-1120.
    • (2007) Mod Pathol , vol.20 , pp. 1113-1120
    • Sur, M.1    AlArdati, H.2    Ross, C.3    Alowami, S.4
  • 13
    • 46049097564 scopus 로고    scopus 로고
    • Expression of VEGF-A/C, VEGF-R2, PDGF-aα/bβ, c-kit, EGFR, Her-2/Neu, Mcl-1 and Bmi-1 in Merkel cell carcinoma
    • Brunner M, Thurnher D, Pammer J, et al. Expression of VEGF-A/C, VEGF-R2, PDGF-aα/bβ, c-kit, EGFR, Her-2/Neu, Mcl-1 and Bmi-1 in Merkel cell carcinoma. Mod Pathol 2008;21:876-884.
    • (2008) Mod Pathol , vol.21 , pp. 876-884
    • Brunner, M.1    Thurnher, D.2    Pammer, J.3
  • 14
    • 31644445651 scopus 로고    scopus 로고
    • Basal cell carcinoma: Biology, morphology and clinical implications
    • Crowson AN. Basal cell carcinoma: biology, morphology and clinical implications. Mod Pathol 2006;19:127-147.
    • (2006) Mod Pathol , vol.19 , pp. 127-147
    • Crowson, A.N.1
  • 15
    • 0030844141 scopus 로고    scopus 로고
    • Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours
    • Dahmane N, Lee J, Robins P, et al. Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours. Nature 1997;389:876-881.
    • (1997) Nature , vol.389 , pp. 876-881
    • Dahmane, N.1    Lee, J.2    Robins, P.3
  • 16
    • 0030802458 scopus 로고    scopus 로고
    • Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog
    • Fan H, Oro AE, Scott MP, Khavari PA. Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog. NatMed 1997;3:788-792.
    • (1997) NatMed , vol.3 , pp. 788-792
    • Fan, H.1    Oro, A.E.2    Scott, M.P.3    Khavari, P.A.4
  • 17
    • 0030685775 scopus 로고    scopus 로고
    • Merkel cell carcinoma: Analysis of clinical, histologic, and immunohistologic features of 132 cases with relation to survival
    • Skelton HG, Smith KJ, Hitchcock CL, et al. Merkel cell carcinoma: analysis of clinical, histologic, and immunohistologic features of 132 cases with relation to survival. J Am Acad Dermatol 1997;37:734-739.
    • (1997) J Am Acad Dermatol , vol.37 , pp. 734-739
    • Skelton, H.G.1    Smith, K.J.2    Hitchcock, C.L.3
  • 18
    • 1842788162 scopus 로고    scopus 로고
    • The basal layer in human squamous tumors harbors more UVA than UVB fingerprint mutations: A role for UVA in human skin carcinogenesis
    • Agar NS, Halliday GM, Barnetson RS, et al. The basal layer in human squamous tumors harbors more UVA than UVB fingerprint mutations: a role for UVA in human skin carcinogenesis. Proc Natl Acad Sci U S A 2004;101:4954-4959.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 4954-4959
    • Agar, N.S.1    Halliday, G.M.2    Barnetson, R.S.3
  • 19
    • 27644510631 scopus 로고    scopus 로고
    • Fate of UVB-induced p53 mutations in SKH-hr1 mouse skin after discontinuation of irradiation: Relationship to skin cancer development
    • Melnikova VO, Pacifico A, Chimenti S, Peris K, Ananthaswamy HN. Fate of UVB-induced p53 mutations in SKH-hr1 mouse skin after discontinuation of irradiation: relationship to skin cancer development. Oncogene 2005; 24:7055-7063.
    • (2005) Oncogene , vol.24 , pp. 7055-7063
    • Melnikova, V.O.1    Pacifico, A.2    Chimenti, S.3    Peris, K.4    Ananthaswamy, H.N.5
  • 20
    • 0032861601 scopus 로고    scopus 로고
    • Ultraviolet radiation mutagenesis of hedgehog pathway genes in basal cell carcinomas
    • Aszterbaum M, Beech J, Epstein EH Jr. Ultraviolet radiation mutagenesis of hedgehog pathway genes in basal cell carcinomas. J Investig Dermatol Symp Proc 1999;4:41-45.
    • (1999) J Investig Dermatol Symp Proc , vol.4 , pp. 41-45
    • Aszterbaum, M.1    Beech, J.2    Epstein Jr., E.H.3
  • 21
    • 0037217819 scopus 로고    scopus 로고
    • TP53 mutations in human skin cancers
    • Giglia-Mari G, Sarasin A. TP53 mutations in human skin cancers. Hum Mutat 2003;21:217-228.
    • (2003) Hum Mutat , vol.21 , pp. 217-228
    • Giglia-Mari, G.1    Sarasin, A.2
  • 22
    • 0037115414 scopus 로고    scopus 로고
    • Significantly high levels of ultraviolet-specific mutations in the smoothened gene in basal cell carcinomas from DNA repair-deficient xeroderma pigmentosum patients
    • Couvé-Privat S, Bouadjar B, Avril MF, Sarasin A, Daya-Grosjean L. Significantly high levels of ultraviolet-specific mutations in the smoothened gene in basal cell carcinomas from DNA repair-deficient xeroderma pigmentosum patients. Cancer Res 2002;62:7186-7189.
    • (2002) Cancer Res , vol.62 , pp. 7186-7189
    • Couvé-Privat, S.1    Bouadjar, B.2    Avril, M.F.3    Sarasin, A.4    Daya-Grosjean, L.5
  • 23
    • 2442715387 scopus 로고    scopus 로고
    • Functional analysis of novel sonic hedgehog gene mutations identified in basal cell carcinomas from xeroderma pigmentosum patients
    • Couvé-Privat S, Le Bret M, Traiffort E, et al. Functional analysis of novel sonic hedgehog gene mutations identified in basal cell carcinomas from xeroderma pigmentosum patients. Cancer Res 2004;64:3559-3565.
    • (2004) Cancer Res , vol.64 , pp. 3559-3565
    • Couvé-Privat, S.1    Le Bret, M.2    Traiffort, E.3
  • 24
    • 0032080853 scopus 로고    scopus 로고
    • Missense mutations in SMOH in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system
    • Reifenberger J, Wolter M, Weber RG, et al. Missense mutations in SMOH in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system. Cancer Res 1998;58:1798-1803.
    • (1998) Cancer Res , vol.58 , pp. 1798-1803
    • Reifenberger, J.1    Wolter, M.2    Weber, R.G.3
  • 25
    • 32144431622 scopus 로고    scopus 로고
    • PTCH gene expression as a potential marker for esophageal squamous cell carcinoma
    • Ishiyama A, Hibi K, Koike, et al. PTCH gene expression as a potential marker for esophageal squamous cell carcinoma. Anticancer Res 2006;26:195-198.
    • (2006) Anticancer Res , vol.26 , pp. 195-198
    • Ishiyama, A.1    Hibi, K.2    Koike3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.