Expression of T-bet and GATA3 in children with acute idiopathic thrombocytopenic purpura

Chinese Journal of Contemporary Pediatrics

Volumn 12, Issue 1, 2010, Pages 29-31

  Ren, Shao Min ^a   Zhang, Chun Xia ^a   Li, Wei Cai ^a  

^a Department of Peditrics   (China)

Author keywords

Child; Cytokine; Idiopathic thrombocytopenic purpura; Th1 Th2; Transcriptional factor

Indexed keywords

BETA ACTIN; GAMMA INTERFERON; INTERLEUKIN 4; MESSENGER RNA; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET;

ARTICLE; BLOOD LEVEL; CELL POLARITY; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; IDIOPATHIC THROMBOCYTOPENIC PURPURA; MALE; POLARIZATION; REMISSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TH1 CELL; TH2 CELL;

CHILD; CHILD, PRESCHOOL; FEMALE; GATA3 TRANSCRIPTION FACTOR; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-4; MALE; PURPURA, THROMBOCYTOPENIC, IDIOPATHIC; RNA, MESSENGER; T-BOX DOMAIN PROTEINS; TH1 CELLS;

EID: 76249103860     PISSN: 10088830     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Paling A, Stetfan DC. Idiopathic thrombcytopenic purpura in childhood: a 10-year audit [J]. Hematology, 2008, 13(3):175-180.
2. Zhou B, Zhao H, Yang RC, Han ZC. Multi-dysfunctional pathophysiology in ITP [J]. Crit Rev Oncol Hematol, 2005, 54(2):107-116.
3. Chinese source
4. Chinese source
5. Chinese source
6. Lametschwandtner G, Biedermann T, Schwärzler C, Günther C, Kund J, Fassl S, et al. Sustained T-bet expression confers polarized human TH2 cells with TH1-like cytokine production and migratory capacities [J]. J Allergy Clin Immunol, 2004, 113(5):987-994.
7. Su RC, Becker AB, Kozyrskyj AL, Hayglass KT. Epigenetic regulation of established human type 1 versus type 2 cytokine responses [J]. J Allergy Clin Immunol, 2008, 121(1):57-63.
8. Inman D, Kawana K, Schust D, Lininger R, Young S. Cyclic regulation of T-Bet and GATA-3 in human endometrium [J]. Reprod Sci, 2008, 15(1):83-90.
9. Chinese source
10. Chinese source
11. Chakir H, Wang H, Lefebvre DE, Webb J, Scott FW. T-bet/GATA3 ratio as a measure of the Th1/Th2 cytokine profile in mixed cell populations: predominant role of GATA-3 [J]. J Immunol Meth, 2003, 278(1-2):157-169.